Abstract: Provided herein is a method of characterising a target polynucleotide as it moves with respect to a nanopore using a motor protein. Also provided are polynucleotide adapters and kits comprising such adapters. The methods, kits and adapters find use in characterising polynucleotides, for example in sequencing.

Abstract: Packaging for an attachable unit for a smoking article The invention relates to packaging (300) for an attachable unit (3) for a smoking article (2) comprising a receiver (301) to receive an attachable unit and a guide (306) for aligning the smoking article with the attachable unit when the attachable unit is received by the receiver such that the attachable unit can be attached to the smoking article. The invention also relates to packaging for an attachable unit for a smoking article comprising a receptacle or receiver in which the attachable unit is receivable and a gripping mechanism (307) to releasably hold the attachable unit within the receptacle or receiver when the attachable unit is received in the receptacle or receiver.

Abstract: Packaging for an attachable unit for a smoking article The invention relates to packaging (300) for an attachable unit (3) for a smoking article (2) comprising a receiver (301) to receive an attachable unit and a guide (306) for aligning the smoking article with the attachable unit when the attachable unit is received by the receiver such that the attachable unit can be attached to the smoking article. The invention also relates to packaging for an attachable unit for a smoking article comprising a receptacle or receiver in which the attachable unit is receivable and a gripping mechanism (307) to releasably hold the attachable unit within the receptacle or receiver when the attachable unit is received in the receptacle or receiver.

Abstract: Packaging for an attachable unit for a smoking article The invention relates to packaging (300) for an attachable unit (3) for a smoking article (2) comprising a receiver (301) to receive an attachable unit and a guide (306) for aligning the smoking article with the attachable unit when the attachable unit is received by the receiver such that the attachable unit can be attached to the smoking article. The invention also relates to packaging for an attachable unit for a smoking article comprising a receptacle or receiver in which the attachable unit is receivable and a gripping mechanism (307) to releasably hold the attachable unit within the receptacle or receiver when the attachable unit is received in the receptacle or receiver.

Abstract: A drinking container assembly can include a reservoir for storing a liquid, a substantially smooth textured drinking apparatus configured to channel the liquid, and a textured surface adjacent to the drinking apparatus.

Abstract: Packaging for an attachable unit for a smoking article The invention relates to packaging (300) for an attachable unit (3) for a smoking article (2) comprising a receiver (301) to receive an attachable unit and a guide (306) for aligning the smoking article with the attachable unit when the attachable unit is received by the receiver such that the attachable unit can be attached to the smoking article. The invention also relates to packaging for an attachable unit for a smoking article comprising a receptacle or receiver in which the attachable unit is receivable and a gripping mechanism (307) to releasably hold the attachable unit within the receptacle or receiver when the attachable unit is received in the receptacle or receiver.

Abstract: A disposable container having an opening configured to receive a liquid and having a consumable retained by an edible food package, the edible food package is connected to an inner wall of the disposable container. The edible food package is configured to dissolve when in contact with a liquid, thereby, releasing the consumable into the disposable cup forming a mixture. The disposable container has a lid with a rotatable barrier member. The rotatable barrier member substantially covers the opening of the disposable container when the lid is connected to the disposable container.

Abstract: A process of water degumming an edible oil (preferably a crude edible oil) comprising the steps of: a) admixing approximately 0.1-5% w/w water with an edible oil (preferably a crude edible oil) and a lipid acyltransferase, b) agitating the admixture for between about 10 minutes and 180 minutes at about 45 to about 900 C, and c) separating the oil phase and the gum phase. Preferably said lipid acyltransferase is a polypeptide having lipid acyltransferase activity which polypeptide is obtained by expression of the nucleotide sequence shown as SEQ ID No. 49 or a nucleotide sequence which as has 70% or more identity therewith; and/or is obtained by expression of a nucleic acid which hybridizes under medium stringency conditions to a nucleic probe comprising the nucleotide sequence shown as SEQ ID No. 49; and/or is a polypeptide having lipid acyltransferase activity which polypeptide comprises the amino acid sequence shown as SEQ ID No. 68 or an amino acid sequence which as has 70% or more identity therewith.

Abstract: The present invention provides genetically modified animals and cells comprising edited chromosomal sequences encoding cytochrome P450 (CYP) proteins. In particular, the animals or cells are generated using a zinc finger nuclease-mediated editing process. The invention also provides zinc finger nucleases that target chromosomal sequence encoding CYP proteins, as well as methods of using the genetically modified animals or cells disclosed herein to screen agents for toxicity and other effects.

Abstract: A process of water degumming an edible oil (preferably a crude edible oil) comprising the steps of: a) admixing approximately 0.1-5% w/w water with an edible oil (preferably a crude edible oil) and a lipid acyltransferase, b) agitating the admixture for between about 10 minutes and 180 minutes at about 45 to about 900 C, and c) separating the oil phase and the gum phase. Preferably said lipid acyltransferase is a polypeptide having lipid acyltransferase activity which polypeptide is obtained by expression of the nucleotide sequence shown as SEQ ID No. 49 or a nucleotide sequence which as has 70% or more identity therewith; and/or is obtained by expression of a nucleic acid which hybridises under medium stringency conditions to a nucleic probe comprising the nucleotide sequence shown as SEQ No. 49; and/or is a polypeptide having lipid acyltransferase activity which polypeptide comprises the amino acid sequence shown as SEQ ID No. 68 or an amino acid sequence which as has 70% or more identity therewith.

Abstract: Compositions and methods for identifying and/or modulating RNA transcripts and/or genes involved in fragile X syndrome and other associated disorders are provided. In particular, RNA targets for fragile X mental retardation protein (FMRP) have been identified by a novel monoclonal antibody to FMRP and a consensus sequence for the RNA binding region has been identified. Arrays for identifying compounds, proteins, nucleotides, and the like that modulate the RNA targets or associated genes are provided. Additionally, methods for modulating RNA targets are provided.

Abstract: Compositions and methods for identifying and/or modulating RNA transcripts and/or genes involved in fragile X syndrome and other associated disorders are provided. In particular, RNA targets for fragile X mental retardation protein (FMRP) have been identified by a novel monoclonal antibody to FMRP and a consensus sequence for the RNA binding region has been identified. Arrays for identifying compounds, proteins, nucleotides, and the like that modulate the RNA targets or associated genes are provided. Additionally, methods for modulating RNA targets are provided.