Patents by Inventor Victoria Carr-Brendel
Victoria Carr-Brendel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8010174Abstract: Systems and methods for minimizing or eliminating transient non-glucose related signal noise due to non-glucose rate limiting phenomenon such as ischemia, pH changes, temperatures changes, and the like. The system monitors a data stream from a glucose sensor and detects signal artifacts that have higher amplitude than electronic or diffusion-related system noise. The system replaces some or the entire data stream continually or intermittently including signal estimation methods that particularly address transient signal artifacts. The system is also capable of detecting the severity of the signal artifacts and selectively applying one or more signal estimation algorithm factors responsive to the severity of the signal artifacts, which includes selectively applying distinct sets of parameters to a signal estimation algorithm or selectively applying distinct signal estimation algorithms.Type: GrantFiled: August 22, 2003Date of Patent: August 30, 2011Assignee: DexCom, Inc.Inventors: Paul V. Goode, Jr., James H. Brauker, Apurv U. Kamath, James Patrick Thrower, Victoria Carr-Brendel
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Patent number: 8005525Abstract: Systems and methods for minimizing or eliminating transient non-glucose related signal noise due to non-glucose rate limiting phenomenon such as ischemia, pH changes, temperatures changes, and the like. The system monitors a data stream from a glucose sensor and detects signal artifacts that have higher amplitude than electronic or diffusion-related system noise. The system replaces some or the entire data stream continually or intermittently including signal estimation methods that particularly address transient signal artifacts. The system is also capable of detecting the severity of the signal artifacts and selectively applying one or more signal estimation algorithm factors responsive to the severity of the signal artifacts, which includes selectively applying distinct sets of parameters to a signal estimation algorithm or selectively applying distinct signal estimation algorithms.Type: GrantFiled: October 14, 2009Date of Patent: August 23, 2011Assignee: DexCom, Inc.Inventors: Paul V. Goode, Jr., James H. Brauker, Apurv U. Kamath, James Patrick Thrower, Victoria Carr-Brendel
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Patent number: 8005524Abstract: Systems and methods for dynamically and intelligently estimating analyte data from a continuous analyte sensor, including receiving a data stream, selecting one of a plurality of algorithms, and employing the selected algorithm to estimate analyte values. Additional data processing includes evaluating the selected estimative algorithms, analyzing a variation of the estimated analyte values based on statistical, clinical, or physiological parameters, comparing the estimated analyte values with corresponding measure analyte values, and providing output to a user. Estimation can be used to compensate for time lag, match sensor data with corresponding reference data, warn of upcoming clinical risk, replace erroneous sensor data signals, and provide more timely analyte information encourage proactive behavior and preempt clinical risk.Type: GrantFiled: March 24, 2010Date of Patent: August 23, 2011Assignee: DexCom, Inc.Inventors: James H. Brauker, Victoria Carr-Brendel, Paul V. Goode, Apurv U. Kamath, James P. Thrower, Ben Xavier
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Patent number: 7998071Abstract: Systems and methods for minimizing or eliminating transient non-glucose related signal noise due to non-glucose rate limiting phenomenon such as ischemia, pH changes, temperatures changes, and the like. The system monitors a data stream from a glucose sensor and detects signal artifacts that have higher amplitude than electronic or diffusion-related system noise. The system replaces some or the entire data stream continually or intermittently including signal estimation methods that particularly address transient signal artifacts. The system is also capable of detecting the severity of the signal artifacts and selectively applying one or more signal estimation algorithm factors responsive to the severity of the signal artifacts, which includes selectively applying distinct sets of parameters to a signal estimation algorithm or selectively applying distinct signal estimation algorithms.Type: GrantFiled: October 14, 2009Date of Patent: August 16, 2011Assignee: DexCom, Inc.Inventors: Paul V. Goode, Jr., James H. Brauker, Apurv U. Kamath, James Patrick Thrower, Victoria Carr-Brendel
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Patent number: 7979104Abstract: Systems and methods for processing sensor analyte data, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. During initial calibration, the analyte sensor data is evaluated over a period of time to determine stability of the sensor. The sensor may be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. The calibration may be updated after evaluating the calibration set for best calibration based on inclusion criteria with newly received reference analyte data. Fail-safe mechanisms are provided based on clinical acceptability of reference and analyte data and quality of sensor calibration. Algorithms provide for optimized prospective and retrospective analysis of estimated blood analyte data from an analyte sensor.Type: GrantFiled: May 26, 2010Date of Patent: July 12, 2011Assignee: DexCom, Inc.Inventors: Apurv U. Kamath, Paul V. Goode, Jr., James H. Brauker, Victoria Carr-Brendel
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Publication number: 20110137601Abstract: Systems and methods for minimizing or eliminating transient non-glucose related signal noise due to non-glucose rate limiting phenomenon such as ischemia, pH changes, temperatures changes, and the like. The system monitors a data stream from a glucose sensor and detects signal artifacts that have higher amplitude than electronic or diffusion-related system noise. The system replaces some or the entire data stream continually or intermittently including signal estimation methods that particularly address transient signal artifacts. The system is also capable of detecting the severity of the signal artifacts and selectively applying one or more signal estimation algorithm factors responsive to the severity of the signal artifacts, which includes selectively applying distinct sets of parameters to a signal estimation algorithm or selectively applying distinct signal estimation algorithms.Type: ApplicationFiled: February 9, 2011Publication date: June 9, 2011Applicant: DexCom, Inc.Inventors: Paul V. Goode, JR., James H. Brauker, Apurv U. Kamath, James Patrick Thrower, Victoria Carr-Brendel
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Publication number: 20110130998Abstract: Systems and methods for minimizing or eliminating transient non-glucose related signal noise due to non-glucose rate limiting phenomenon such as ischemia, pH changes, temperatures changes, and the like. The system monitors a data stream from a glucose sensor and detects signal artifacts that have higher amplitude than electronic or diffusion-related system noise. The system replaces some or the entire data stream continually or intermittently including signal estimation methods that particularly address transient signal artifacts. The system is also capable of detecting the severity of the signal artifacts and selectively applying one or more signal estimation algorithm factors responsive to the severity of the signal artifacts, which includes selectively applying distinct sets of parameters to a signal estimation algorithm or selectively applying distinct signal estimation algorithms.Type: ApplicationFiled: February 9, 2011Publication date: June 2, 2011Applicant: DexCom, Inc.Inventors: Paul V. Goode, JR., James H. Brauker, Apurv U. Kamath, James Patrick Thrower, Victoria Carr-Brendel
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Publication number: 20110130971Abstract: Systems and methods for minimizing or eliminating transient non-glucose related signal noise due to non-glucose rate limiting phenomenon such as ischemia, pH changes, temperatures changes, and the like. The system monitors a data stream from a glucose sensor and detects signal artifacts that have higher amplitude than electronic or diffusion-related system noise. The system replaces some or the entire data stream continually or intermittently including signal estimation methods that particularly address transient signal artifacts. The system is also capable of detecting the severity of the signal artifacts and selectively applying one or more signal estimation algorithm factors responsive to the severity of the signal artifacts, which includes selectively applying distinct sets of parameters to a signal estimation algorithm or selectively applying distinct signal estimation algorithms.Type: ApplicationFiled: February 9, 2011Publication date: June 2, 2011Applicant: DexCom, Inc.Inventors: Paul V. Goode, JR., James H. Brauker, Apurv U. Kamath, James Patrick Thrower, Victoria Carr-Brendel
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Publication number: 20110130970Abstract: Systems and methods for minimizing or eliminating transient non-glucose related signal noise due to non-glucose rate limiting phenomenon such as ischemia, pH changes, temperatures changes, and the like. The system monitors a data stream from a glucose sensor and detects signal artifacts that have higher amplitude than electronic or diffusion-related system noise. The system replaces some or the entire data stream continually or intermittently including signal estimation methods that particularly address transient signal artifacts. The system is also capable of detecting the severity of the signal artifacts and selectively applying one or more signal estimation algorithm factors responsive to the severity of the signal artifacts, which includes selectively applying distinct sets of parameters to a signal estimation algorithm or selectively applying distinct signal estimation algorithms.Type: ApplicationFiled: February 9, 2011Publication date: June 2, 2011Applicant: DexCom, Inc.Inventors: Paul V. Goode, JR., James H. Brauker, Apurv U. Kamath, James Patrick Thrower, Victoria Carr-Brendel
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Publication number: 20110124997Abstract: Systems and methods for minimizing or eliminating transient non-glucose related signal noise due to non-glucose rate limiting phenomenon such as ischemia, pH changes, temperatures changes, and the like. The system monitors a data stream from a glucose sensor and detects signal artifacts that have higher amplitude than electronic or diffusion-related system noise. The system replaces some or the entire data stream continually or intermittently including signal estimation methods that particularly address transient signal artifacts. The system is also capable of detecting the severity of the signal artifacts and selectively applying one or more signal estimation algorithm factors responsive to the severity of the signal artifacts, which includes selectively applying distinct sets of parameters to a signal estimation algorithm or selectively applying distinct signal estimation algorithms.Type: ApplicationFiled: January 27, 2011Publication date: May 26, 2011Applicant: DexCom, Inc.Inventors: Paul V. Goode, JR., James H. Brauker, Apurv U. Kamath, James Patrick Thrower, Victoria Carr-Brendel
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Publication number: 20110125410Abstract: Systems and methods for minimizing or eliminating transient non-glucose related signal noise due to non-glucose rate limiting phenomenon such as ischemia, pH changes, temperatures changes, and the like. The system monitors a data stream from a glucose sensor and detects signal artifacts that have higher amplitude than electronic or diffusion-related system noise. The system replaces some or the entire data stream continually or intermittently including signal estimation methods that particularly address transient signal artifacts. The system is also capable of detecting the severity of the signal artifacts and selectively applying one or more signal estimation algorithm factors responsive to the severity of the signal artifacts, which includes selectively applying distinct sets of parameters to a signal estimation algorithm or selectively applying distinct signal estimation algorithms.Type: ApplicationFiled: January 27, 2011Publication date: May 26, 2011Applicant: DexCom, Inc.Inventors: Paul V. Goode, JR., James H. Brauker, Apurv U. Kamath, James Patrick Thrower, Victoria Carr-Brendel
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Publication number: 20110124992Abstract: An implantable sensor for use in measuring a concentration of an analyte such as glucose in a bodily fluid, including a body with a sensing region adapted for transport of analytes between the sensor and the bodily fluid, wherein the sensing region is located on a curved portion of the body such that when a foreign body capsule forms around the sensor, a contractile force is exerted by the foreign body capsule toward the sensing region. The body is partially or entirely curved, partially or entirely covered with an anchoring material for supporting tissue ingrowth, and designed for subcutaneous tissue implantation. The geometric design, including curvature, shape, and other factors minimize chronic inflammatory response at the sensing region and contribute to improved performance of the sensor in vivo.Type: ApplicationFiled: January 28, 2011Publication date: May 26, 2011Applicant: DexCom, Inc.Inventors: James H. Brauker, Victoria Carr-Brendel, Paul V. Neale, Laura A. Martinson, Mark A. Tapsak
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Publication number: 20110118579Abstract: Systems and methods for minimizing or eliminating transient non-glucose related signal noise due to non-glucose rate limiting phenomenon such as ischemia, pH changes, temperatures changes, and the like. The system monitors a data stream from a glucose sensor and detects signal artifacts that have higher amplitude than electronic or diffusion-related system noise. The system replaces some or the entire data stream continually or intermittently including signal estimation methods that particularly address transient signal artifacts. The system is also capable of detecting the severity of the signal artifacts and selectively applying one or more signal estimation algorithm factors responsive to the severity of the signal artifacts, which includes selectively applying distinct sets of parameters to a signal estimation algorithm or selectively applying distinct signal estimation algorithms.Type: ApplicationFiled: January 27, 2011Publication date: May 19, 2011Applicant: DexCom, Inc.Inventors: Paul V. Goode, JR., James H. Brauker, Apurv U. Kamath, James Patrick Thrower, Victoria Carr-Brendel
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Publication number: 20110118580Abstract: Systems and methods for minimizing or eliminating transient non-glucose related signal noise due to non-glucose rate limiting phenomenon such as ischemia, pH changes, temperatures changes, and the like. The system monitors a data stream from a glucose sensor and detects signal artifacts that have higher amplitude than electronic or diffusion-related system noise. The system replaces some or the entire data stream continually or intermittently including signal estimation methods that particularly address transient signal artifacts. The system is also capable of detecting the severity of the signal artifacts and selectively applying one or more signal estimation algorithm factors responsive to the severity of the signal artifacts, which includes selectively applying distinct sets of parameters to a signal estimation algorithm or selectively applying distinct signal estimation algorithms.Type: ApplicationFiled: January 27, 2011Publication date: May 19, 2011Applicant: DexCom, Inc.Inventors: Paul V. Goode, JR., James H. Brauker, Apurv U. Kamath, James Patrick Thrower, Victoria Carr-Brendel
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Patent number: 7935057Abstract: Systems and methods for minimizing or eliminating transient non-glucose related signal noise due to non-glucose rate limiting phenomenon such as ischemia, pH changes, temperatures changes, and the like. The system monitors a data stream from a glucose sensor and detects signal artifacts that have higher amplitude than electronic or diffusion-related system noise. The system replaces some or the entire data stream continually or intermittently including signal estimation methods that particularly address transient signal artifacts. The system is also capable of detecting the severity of the signal artifacts and selectively applying one or more signal estimation algorithm factors responsive to the severity of the signal artifacts, which includes selectively applying distinct sets of parameters to a signal estimation algorithm or selectively applying distinct signal estimation algorithms.Type: GrantFiled: January 14, 2009Date of Patent: May 3, 2011Assignee: DexCom, Inc.Inventors: Paul V. Goode, Jr., James H. Brauker, Apurv U. Kamath, James Patrick Thrower, Victoria Carr-Brendel
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Patent number: 7914450Abstract: Systems and methods for processing sensor analyte data, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. During initial calibration, the analyte sensor data is evaluated over a period of time to determine stability of the sensor. The sensor may be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. The calibration may be updated after evaluating the calibration set for best calibration based on inclusion criteria with newly received reference analyte data. Fail-safe mechanisms are provided based on clinical acceptability of reference and analyte data and quality of sensor calibration. Algorithms provide for optimized prospective and retrospective analysis of estimated blood analyte data from an analyte sensor.Type: GrantFiled: May 3, 2010Date of Patent: March 29, 2011Assignee: DexCom, Inc.Inventors: Paul V. Goode, Jr., James H. Brauker, Apurv U. Kamath, Victoria Carr-Brendel
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Patent number: 7881763Abstract: An implantable sensor for use in measuring a concentration of an analyte such as glucose in a bodily fluid, including a body with a sensing region adapted for transport of analytes between the sensor and the bodily fluid, wherein the sensing region is located on a curved portion of the body such that when a foreign body capsule forms around the sensor, a contractile force is exerted by the foreign body capsule toward the sensing region. The body is partially or entirely curved, partially or entirely covered with an anchoring material for supporting tissue ingrowth, and designed for subcutaneous tissue implantation. The geometric design, including curvature, shape, and other factors minimize chronic inflammatory response at the sensing region and contribute to improved performance of the sensor in vivo.Type: GrantFiled: May 2, 2006Date of Patent: February 1, 2011Assignee: DexCom, Inc.Inventors: James H. Brauker, Victoria Carr-Brendel, Paul V. Neale, Laura A. Martinson, Mark A. Tapsak
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Patent number: 7875293Abstract: A biointerface membrane for an implantable device including a nonresorbable solid portion with a plurality of interconnected cavities therein adapted to support tissue ingrowth in vivo, and a bioactive agent incorporated into the biointerface membrane and adapted to modify the tissue response is provided. The bioactive agents can be chosen to induce vascularization and/or prevent barrier cell layer formation in vivo, and are advantageous when used with implantable devices wherein solutes are transported across the device-tissue interface.Type: GrantFiled: May 10, 2004Date of Patent: January 25, 2011Assignee: DexCom, Inc.Inventors: Mark Shults, James H. Brauker, Victoria Carr-Brendel, Mark Tapsak, Dubravka Markovic
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Patent number: 7860545Abstract: An implantable analyte-measuring device including a membrane adapted to promote vascularization and/or interfere with barrier cell layer formation. The membrane includes any combination of materials, architecture, and bioactive agents that facilitate analyte transport to provide long-term in vivo performance of the implantable analyte-measuring device.Type: GrantFiled: February 26, 2008Date of Patent: December 28, 2010Assignee: DexCom, Inc.Inventors: Mark C. Shults, James H. Brauker, Victoria Carr-Brendel, Mark A. Tapsak, Dubravka Markovic, Stuart J. Updike, Rathbun K. Rhodes
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Patent number: 7828728Abstract: The present invention relates generally to membranes utilized with implantable devices, such as devices for the detection of analyte concentrations in a biological sample. More particularly, the invention relates to novel silicone-hydrophilic polymer blend membranes, and to devices and implantable devices including these membranes.Type: GrantFiled: February 14, 2007Date of Patent: November 9, 2010Assignee: DexCom, Inc.Inventors: Robert Boock, Monica Rixman, James H. Brauker, James R. Petisce, Peter C. Simpson, Mark Brister, Mark A. Tapsak, Victoria Carr-Brendel