Abstract: Methods of characterizing an analyte using a detector such as a nanopore and an enzyme are provided. One aspect features methods for characterizing a double-stranded polynucleotide using a detector, e.g., without using a hairpin connecting a template and a complement of the double-stranded polynucleotide. Another aspect features methods for characterizing an analyte using a tag-modified nanopore with increased sensitivity and/or higher throughput. Compositions and systems including, e.g., adaptors for attachment to double-stranded polynucleotides and tag-modified nanopores, which can be used in the methods are also provided.

Abstract: A support structure for an aircraft includes a structural member having a generally planar shape, a longitudinal axis defining a longitudinal direction and a transverse axis orthogonal to the longitudinal axis, and a plurality of rounded holes formed along the longitudinal direction. Each rounded hole has a respective major axis with a major length and a minor axis orthogonal to the major axis with a minor length that is less than the major length. Each rounded hole is oriented with its major axis rotated more than 0 degrees and less than 90 degrees from the longitudinal axis of the structural member. The structural member is configured for bearing external loads acting on the structural member in a principal loading direction that is not parallel with the longitudinal axis or the transverse axis. Each rounded hole may be oriented with its major axis aligned generally parallel with the principal loading direction.

Abstract: The invention is a travel pillow constructed so a user can affix the pillow to a vehicle window or other smooth surface by using suction cups or any other location where a user may wish for a padded surface. The pillow is constructed so it is easily configured in multiple ways using magnets sewn within the cushions, constructed so the side cushions are thicker than its central cushions to provide a comfortable position for a user's head to rest.

Abstract: The invention is a travel pillow constructed so a user can affix the pillow to a vehicle window or other smooth surface by using suction cups or any other location where a user may wish for a padded surface. The pillow is constructed so it is easily configured in multiple ways using magnets sewn within the cushions, constructed so the side cushions are thicker than its central cushions to provide a comfortable position for a user's head to rest.