Abstract: Devices, and methods of use thereof, are provided for the collection of a biological sample during insertion into a human orifice. The device may include a body piece, an insertion piece extending from one end of the body piece, and a handle connected to the other end of the body piece. Upon rotation of the handle, a shaft housed within the body piece, with a collection end at a distal portion thereof, is extended from a retracted position to an extended position, such that the collection end exits an opening within the insertion piece. The angle of the body piece relative to the insertion piece may be configured for self-sampling of a vaginal sample in a seated position. The collection end may be a swab with a plurality of pinwheeling fins having leading edge oriented to collect the biological sample when the shaft is rotated in a given direction.

Abstract: Various example specimen collecting devices are disclosed for the collection of biological samples. The specimen collection device is comprised of an elongate shaft and a distal sampling member, where the distal sampling member includes a plurality of bristles for collecting and sampling a biological fluid. Various example embodiments are provided in which the bristles of the distal sampling member are spatially configured and oriented for collection and elution of biological fluids that may contain cells, such as vaginal fluids.

Abstract: Disclosed is a specimen collecting device for collecting cell samples. The specimen collecting device has an extendible swab which can be extended and retracted during use. The extendible swab can also be inserted into the handle so that the samples can be stored, at least temporarily.