Patents by Inventor Victoria K. Lombardo

Victoria K. Lombardo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and compositions for the treatment of body composition disorders
    Publication number: 20080200458
    Abstract: This invention relates to methods of treating, managing and preventing body composition disorders, and to compounds and pharmaceutical compositions useful in such methods.
    Type: Application
    Filed: January 17, 2008
    Publication date: August 21, 2008
    Inventors: Joseph Barbosa, Simon D.P. Baugh, Qiang Han, Victoria K. Lombardo, Huy Van Nguyen, Praveen K. Pabba, Kristen M. Terranova
  • Methods and compositions for the treatment of pain, inflammation and cancer
    Publication number: 20080194557
    Abstract: This invention relates to methods of treating, managing and preventing pain, inflammation, cancer, and ocular diseases and disorders, and to compounds and pharmaceutical compositions useful in such methods.
    Type: Application
    Filed: January 17, 2008
    Publication date: August 14, 2008
    Inventors: Joseph Barbosa, Simon D.P. Baugh, Qiang Han, Victoria K. Lombardo, Huy Van Nguyen, Praveen K. Pabba, Kristen M. Terranova
  • Arylthiazolidinedione derivatives
    Patent number: 6465497
    Abstract: Substituted 5-aryl-2,4-thiazolidinediones and oxazolidinediones are potent agonists of PPAR, and are therefore useful in the treatment, control or prevention of diabetes, hyperglycemia, hyperlipidemia (including hypercholesterolemia and hypertriglyceridemia), atherosclerosis, obesity, vascular restenosis, and other PPAR &agr; and/or &ggr; mediated diseases, disorders and conditions.
    Type: Grant
    Filed: November 21, 2001
    Date of Patent: October 15, 2002
    Assignee: Merck & Co., Inc.
    Inventors: Ranjit C. Desai, Soumya P. Sahoo, Jeffrey P. Bergman, Victoria K. Lombardo, Edward J. Metzger, Hiroo Koyama
  • Arylthiazolidinedione and aryloxazolidinedione derivatives
    Patent number: 6399640
    Abstract: Substituted 5-aryl-2,4-thiazolidinediones or 5-aryl-2,4-oxazolidinediones that also carry a second substituent in the 5-position of the heterocyclic ring are potent agonists of PPAR, and are therefore useful in the treatment, control or prevention of diabetes, hyperglycemia, hyperlipidemia (including hypercholesterolemia and hypertriglyceridemia), atherosclerosis, obesity, vascular restenosis, and other PPAR &agr;, &dgr; and/or &ggr; mediated diseases, disorders and conditions.
    Type: Grant
    Filed: June 16, 2000
    Date of Patent: June 4, 2002
    Assignee: Merck & Co., Inc.
    Inventors: Soumya P. Sahoo, Conrad Santini, Julia K. Boueres, James V. Heck, Edward Metzger, Victoria K. Lombardo
  • Arylthiazolidinedione and aryloxazolidinedione derivatives
    Patent number: 6380191
    Abstract: Substituted 5-aryl-2,4-thiazolidinediones and oxazolidinediones are potent agonists of PPAR, and are therefore useful in the treatment, control or prevention of diabetes, hyperglycemia, hyperlipidemia (including hypercholesterolemia and hypertriglyceridemia), atherosclerosis, obesity, vascular restenosis, and other PPAR &agr; and/or &ggr; mediated diseases, disorders and conditions.
    Type: Grant
    Filed: June 16, 2000
    Date of Patent: April 30, 2002
    Assignee: Merck & Co. Inc.
    Inventors: Ranjit C. Desai, Soumya P. Sahoo, Jeffrey P. Bergman, Victoria K. Lombardo, Edward J. Metzger, Hiroo Koyama
  • Arylthiazolidinedione derivatives
    Publication number: 20020037911
    Abstract: Substituted 5-aryl-2,4-thiazolidinediones and oxazolidinediones are potent agonists of PPAR, and are therefore useful in the treatment, control or prevention of diabetes, hyperglycemia, hyperlipidemia (including hypercholesterolemia and hypertriglyceridemia), atherosclerosis, obesity, vascular restenosis, and other PPAR &agr; and/or &ggr; mediated diseases, disorders and conditions.
    Type: Application
    Filed: November 21, 2001
    Publication date: March 28, 2002
    Applicant: Merck & Co., Inc.
    Inventors: Ranjit C. Desai, Soumya P. Sahoo, Jeffrey P. Bergman, Victoria K. Lombardo, Edward J. Metzger, Hiroo Koyama
  • Arylthiazolidinedione derivitives
    Patent number: 6200998
    Abstract: Substituted 5-aryl-2,4-thiazolidinediones are potent agonists of PPAR, and are therefore useful in the treatment, control or prevention of diabetes, hyperglycemia, hyperlipidemia (including hypercholesterolemia and hypertriglyceridemia), atherosclerosis, obesity, vascular restenosis, and other PPAR &agr;, &dgr; and/or &ggr; mediated diseases, disorders and conditions.
    Type: Grant
    Filed: November 23, 1999
    Date of Patent: March 13, 2001
    Assignee: Merck & Co., Inc.
    Inventors: Soumya P. Sahoo, Wei Han, Richard L. Tolman, Jeffrey Bergman, Conrad Santini, Ranjit Desai, Victoria K. Lombardo, Julia K. Boueres, Dominick F. Gratale
  • Arylthiazolidinedione derivatives
    Patent number: 6008237
    Abstract: Substituted 5-aryl-2,4-thiazolidinediones are potent agonists of PPAR, and are therefore useful in the treatment, control or prevention of diabetes, hyperglycemia, hyperlipidemia (including hypercholesterolemia and hypertriglyceridemia), atherosclerosis, obesity, vascular restenosis, and other PPAR .alpha., .delta. and/or .gamma. mediated diseases, disorders and conditions.
    Type: Grant
    Filed: December 17, 1998
    Date of Patent: December 28, 1999
    Assignee: Merck & Co., Inc.
    Inventors: Soumya P. Sahoo, Richard L. Tolman, Wei Han, Jeffrey Bergman, Conrad Santini, Victoria K. Lombardo, Ranjit Desai, Julia K. Boueres, Dominick F. Gratale
  • Inhibitors of peptide binding to MHO class II proteins
    Patent number: 5817757
    Abstract: Compounds of the formula ##STR1## are inhibitors of peptide binding to major histocompatibility complex type II proteins and are useful in the treatment and prevention of autoimmune diseases including: rheumatoid arthritis, Type I diabetes, multiple sclerosis, lupus erythematosis, Graves disease and pemphigus. The present invention also provides novel compositions, methods of treatment employing the compounds of the present invention and methods of manufacture of the compounds of structural formula (I).
    Type: Grant
    Filed: October 28, 1996
    Date of Patent: October 6, 1998
    Assignee: Merck & Co., Inc.
    Inventors: Alan D. Adams, A. Brian Jones, Victoria K. Lombardo, Richard L. Tolman