Patents by Inventor VICTORIA V. LUNYAK

VICTORIA V. LUNYAK has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • H1.0K180ME2 ANTIBODIES, METHODS OF MAKING AND USES THEREOF
    Publication number: 20230279147
    Abstract: Provided herein are antibodies that specifically bind a protein comprising an H1.0K180me2 antigen or a peptide thereof, methods of making such antibodies, and methods of using such antibodies for therapeutics and diagnostics.
    Type: Application
    Filed: November 10, 2022
    Publication date: September 7, 2023
    Inventors: Victoria V. LUNYAK, James Robert TOLLERVEY
  • H1.0K180me2 antibodies, methods of making and uses thereof
    Patent number: 11505621
    Abstract: Provided herein are antibodies that specifically bind a protein comprising an H1.0K180me2 antigen or a peptide thereof, methods of making such antibodies, and methods of using such antibodies for therapeutics and diagnostics.
    Type: Grant
    Filed: April 23, 2020
    Date of Patent: November 22, 2022
    Assignee: AELAN CELL TECHNOLOGIES, INC.
    Inventors: Victoria V. Lunyak, James Robert Tollervey
  • H1.0K180ME2 ANTIBODIES, METHODS OF MAKING AND USES THEREOF
    Publication number: 20200362056
    Abstract: Provided herein are antibodies that specifically bind a protein comprising an H1.0K180me2 antigen or a peptide thereof, methods of making such antibodies, and methods of using such antibodies for therapeutics and diagnostics.
    Type: Application
    Filed: April 23, 2020
    Publication date: November 19, 2020
    Applicants: Aelan Cell Technologies, Inc., Aelan Cell Technologies, Inc.
    Inventors: Victoria V. LUNYAK, James Robert TOLLERVEY
  • DOWNREGULATION OF SINE/ALU RETROTRANSPOSON TRANSCRIPTION TO INDUCE OR RESTORE PROLIFERATIVE CAPACITY AND/OR PLURIPOTENCY TO A STEM CELL
    Publication number: 20170283770
    Abstract: In certain embodiments methods are provided for inducing and/or restoring and/or maintaining a non-senescent phenotype, or aspects thereof (e.g., proliferative capacity and/or pluripotency) in a mammalian cell. The methods typically involve reducing the level or activity of SINE/Alu retrotransposon transcripts in the cell in an amount sufficient to induce or restore proliferative capacity and/or pluripotency to said mammalian cell.
    Type: Application
    Filed: February 28, 2017
    Publication date: October 5, 2017
    Inventor: Victoria V. LUNYAK
  • Downregulation of SINE/ALU retrotransposon transcription to induce or restore proliferative capacity and/or pluripotency to a stem cell
    Patent number: 9617514
    Abstract: In certain embodiments methods are provided for inducing and/or restoring and/or maintaining a non-senescent phenotype, or aspects thereof (e.g., proliferative capacity and/or pluripotency) in a mammalian cell. The methods typically involve reducing the level or activity of SINE/Alu retrotransposon transcripts in the cell in an amount sufficient to induce or restore proliferative capacity and/or pluripotency to said mammalian cell.
    Type: Grant
    Filed: October 20, 2011
    Date of Patent: April 11, 2017
    Assignee: BUCK INSTITUTE FOR RESEARCH ON AGING
    Inventor: Victoria V. Lunyak
  • Epigenetic mechanisms related to DNA damage and aging
    Patent number: 8981066
    Abstract: This invention pertains to markers of cellular senescence. In particular methylation of histone H1 (or isoforms thereof) at residue 172 and/or at residue 180 is a marker of cellular senescence. Antibodies specific to histone H1 (or isoforms thereof) methylated at residue 172 and/or at residue 180 are provided.
    Type: Grant
    Filed: August 23, 2012
    Date of Patent: March 17, 2015
    Assignee: Buck Institute for Research on Aging
    Inventor: Victoria V. Lunyak
  • DOWNREGULATION OF SINE/ALU RETROTRANSPOSON TRANSCRIPTION TO INDUCE OR RESTORE PROLIFERATIVE CAPACITY AND/OR PLURIPOTENCY TO A STEM CELL
    Publication number: 20130344603
    Abstract: In certain embodiments methods are provided for inducing and/or restoring and/or maintaining a non-senescent phenotype, or aspects thereof (e.g., proliferative capacity and/or pluripotency) in a mammalian cell. The methods typically involve reducing the level or activity of SINE/Alu retrotransposon transcripts in the cell in an amount sufficient to induce or restore proliferative capacity and/or pluripotency to said mammalian cell.
    Type: Application
    Filed: October 20, 2011
    Publication date: December 26, 2013
    Applicant: BUCK INSTITUTE FOR RESEARCH ON AGING
    Inventor: Victoria V. Lunyak
  • NOVEL EPIGENETIC MECHANISMS RELATED TO DNA DAMAGE AND AGING
    Publication number: 20130065254
    Abstract: This invention pertains to markers of cellular senescence. In particular methylation of histone H1 (or isoforms thereof) at residue 172 and/or at residue 180 is a marker of cellular senescence. Antibodies specific to histone H1 (or isoforms thereof) methylated at residue 172 and/or at residue 180 are provided.
    Type: Application
    Filed: August 23, 2012
    Publication date: March 14, 2013
    Applicant: BUCK INSTITUTE FOR RESEARCH ON AGING
    Inventor: VICTORIA V. LUNYAK