Abstract: The present provides in one aspect for a biological specimen collection apparatus comprising a biological specimen sampler and a storage and transport container. The biological specimen sampler has a means for holding the sampler by a person taking the sample from a subject and a biological specimen sample collection zone located distal of the holding means, the sample collection zone being separable from the holding means. The storage and transport container is provided in its interior with a means for gripping the sample collection zone to separate the sample collection zone from the holding means such that only the sample collection zone is retained in the interior of the storage and transport container. Preferrably a sealing cap for the storage and transport container for a biological sample is also provided, the sealing cap having a reagent dispenser integrated therewith, the reagent dispenser being capable of dispensing reagent into the container in a controlled manner.