Patents by Inventor Vidanagamage Chandana Epa

Vidanagamage Chandana Epa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • AMYLOID-BETA PEPTIDE CRYSTAL STRUCTURE
    Publication number: 20140039155
    Abstract: The invention relates provides a novel crystal structure of the fibrillogenic part of amyloid ?-peptide (A?). More specifically the crystal structure is A?-IgNAR and, accordingly the present invention also relates to selecting and/or designing compounds that modulate amyloid ?-peptide (A?) activity using techniques such as in silico screening and crystal soaking experiments. The invention further relates to compounds and methods for inhibiting interaction between amyloid ?-peptide (A?) monomers, more particularly, inhibiting or disrupting amyloid ?-peptide (A?) oligomer formation and toxic activity.
    Type: Application
    Filed: August 9, 2013
    Publication date: February 6, 2014
    Applicant: Commonwealth Scientific and Industrial Research Organisation
    Inventors: Stewart Douglas NUTTALL, Victor Anatolievich STRELTSOV, Joseph Noozhumurry VARGHESE, Vidanagamage Chandana EPA
  • Amyloid-beta peptide crystal structure
    Patent number: 8524863
    Abstract: The invention relates provides a novel crystal structure of the fibrillogenic part of amyloid ?-peptide (A?). More specifically the crystal structure is A?-IgNAR and, accordingly the present invention also relates to selecting and/or designing compounds that modulate amyloid ?-peptide (A?) activity using techniques such as in silico screening and crystal soaking experiments. The invention further relates to compounds and methods for inhibiting interaction between amyloid ?-peptide (A?) monomers, more particularly, inhibiting or disrupting amyloid ?-peptide (A?) oligomer formation and toxic activity.
    Type: Grant
    Filed: October 6, 2009
    Date of Patent: September 3, 2013
    Assignee: Commonwealth Scientific and Industrial Research Organisation
    Inventors: Stewart Douglas Nuttall, Victor Anatolievich Streltsov, Joseph Noozhumurry Varghese, Vidanagamage Chandana Epa
  • AMYLOID-BETA PEPTIDE CRYSTAL STRUCTURE
    Publication number: 20110269938
    Abstract: The invention relates provides a novel crystal structure of the fibrillogenic part of amyloid ?-peptide (A?). More specifically the crystal structure is A?-IgNAR and, accordingly the present invention also relates to selecting and/or designing compounds that modulate amyloid ?-peptide (A?) activity using techniques such as in silico screening and crystal soaking experiments. The invention further relates to compounds and methods for inhibiting interaction between amyloid ?-peptide (A?) monomers, more particularly, inhibiting or disrupting amyloid ?-peptide (A?) oligomer formation and toxic activity.
    Type: Application
    Filed: October 6, 2009
    Publication date: November 3, 2011
    Applicant: Commonwealth Scientific and Industrial Research Organisation
    Inventors: Stewart Douglas Nuttall, Victor Anatolievich Streltsov, Joseph Noozhumurry Varghese, Vidanagamage Chandana Epa
  • Method of designing agonists and antagonists to EGF receptor family
    Patent number: 6941229
    Abstract: The present invention relates to a method of designing compounds able to bind to a molecule of the EGF receptor family and to modulate the activity mediated by the receptor molecule based on the 3-D structure coordinates of the EGF receptor crystal of FIG. 6.
    Type: Grant
    Filed: May 31, 1999
    Date of Patent: September 6, 2005
    Assignees: Commonwealth Scientific and Industrial Research Organization, Ludwig Institute for Cancer Research
    Inventors: Thomas Charles Elleman, Vidanagamage Chandana Epa, Thomas Peter John Garrett, Robert Nicholas Jorissen, Meizhen Lou, Antony Wilks Burgess, Neil Moreton McKern, Herbert Rudolf Treutlein, Colin Lesley Ward