Patents by Inventor Vidar Bjornstad

Vidar Bjornstad has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SYNTHESIS PROCESS
    Publication number: 20240083950
    Abstract: An optimized method for synthesizing dalbavancin is provided in which an organic antisolvent such as tert-butyl methyl ether (TBME) or dimethoxyethane (DME) is used to precipitate the product of the esterification of A-40926.
    Type: Application
    Filed: January 10, 2022
    Publication date: March 14, 2024
    Inventors: Vidar Bjørnstad, Karl James Bonney
  • Low substituted polymyxins and compositions thereof
    Patent number: 10711040
    Abstract: The present invention relates to novel low substituted polymyxins and compositions thereof.
    Type: Grant
    Filed: June 29, 2015
    Date of Patent: July 14, 2020
    Assignee: XELLIA PHARMACEUTICALS APS
    Inventors: Vidar Bjornstad, Solvi Gunnes, Torben Koch, Claes Melander
  • Polymyxins, compositions, methods of making and methods of use
    Patent number: 10640536
    Abstract: Disclosed herein is a composition comprising at least one polymyxin or a salt thereof represented by formula (I) wherein R1 is an aliphatic linear or branched C6-C10 acyl group, or (I?) R5 is —CH(CH3)2, —CH2CH(CH3)2, —CH(CH3)CH2CH3, or —CH2C6H5; R6 is —CH(CH3)2, —CH2CH(CH3)2, or —CH(CH3)CH2CH3; each of R2, R3, R4, R7 and R8 is either —(CH2)xCH2NH2 or —(CH2)xCH2N(CH2SO3M)2; wherein x is 0 or 1; wherein M is a monovalent cation; and wherein at least three of R2, R3, R4, R7 and R8 are —(CH2)xCH2N(CH2SO3M)2.
    Type: Grant
    Filed: January 9, 2014
    Date of Patent: May 5, 2020
    Assignee: XELLIA PHARMACEUTICALS APS
    Inventors: Solvi Gunnes, Vidar Bjornstad, Torben Koch, Claes Melander, Martin Mansson
  • LOW SUBSTITUTED POLYMYXINS AND COMPOSITIONS THEREOF
    Publication number: 20170218024
    Abstract: The present invention relates to novel low substituted polymyxins and compositions thereof.
    Type: Application
    Filed: June 29, 2015
    Publication date: August 3, 2017
    Inventors: VIDAR BJORNSTAD, SOLVI GUNNES, TORBEN KOCH, CLAES MELANDER
  • 2-amino-3-methyl-hex-5-enoic acid and its use in the production of peptides including bacitracins
    Patent number: 9272983
    Abstract: The present invention concerns 2-amino-3-methyl-hex-5-enoic acid, its use for the production of peptides such as bacitracins and a method for producing it.
    Type: Grant
    Filed: September 30, 2010
    Date of Patent: March 1, 2016
    Assignee: XELLIA PHARMACEUTICALS APS
    Inventors: Martin Mansson, Christine Senstad, Jon Efskind, Vidar Bjornstad
  • 2-AMINO-3-METHYL-HEX-5-ENOIC ACID AND ITS USE IN THE PRODCTION OF PEPTIDES SUCH AS BACITRACINS
    Publication number: 20160031798
    Abstract: The present invention concerns 2-amino-3-mmethyl-hex-5-enoic acid, its use for the production of peptides such as bacitracins and a method for producing it.
    Type: Application
    Filed: September 9, 2015
    Publication date: February 4, 2016
    Inventors: Martin Mansson, Christine Senstad, Jon Efskind, Vidar Bjornstad
  • POLYMYXINS, COMPOSITIONS, METHODS OF MAKING AND METHODS OF USE
    Publication number: 20160002296
    Abstract: Disclosed herein is a composition comprising at least one polymyxin or a salt thereof represented by formula (I) wherein R1 is an aliphatic linear or branched C6-C10 acyl group, or (I?) R5 is —CH(CH3)2, —CH2CH(CH3)2, —CH(CH3)CH2CH3, or —CH2C6H5; R6 is —CH(CH3)2, —CH2CH(CH3)2, or —CH(CH3)CH2CH3; each of R2, R3, R4, R7 and R8 is either —(CH2)XCH2NH2 or —(CH2)xCH2N(CH2SO3M)2; wherein x is 0 or 1; wherein M is a monovalent cation; and wherein at least three of R2, R3, R4, R7 and R are —(CH2)xCH2N(CH2SO3M)2.
    Type: Application
    Filed: January 9, 2014
    Publication date: January 7, 2016
    Inventors: SOLVI GUNNES, VIDAR BJORNSTAD, TORBEN KOCH, CLAES MELANDER, MARTIN MANSSON
  • 2-Amino-3-methyl-hex-5-enoic acid and its use in the prodction of peptides such as bacitracins
    Publication number: 20120202968
    Abstract: The present invention concerns 2-amino-3-methyl-hex-5-enoic acid, its use for the production of peptides such as bacitracins and a method for producing it.
    Type: Application
    Filed: September 30, 2010
    Publication date: August 9, 2012
    Applicant: XELLIA PHARMACEUTICALS APS
    Inventors: Martin Mansson, Christine Senstad, Jon Efskind, Vidar Bjornstad
  • Purine nucleotide derivatives
    Patent number: 8153609
    Abstract: This invention provides novel 8-carbyl substituted cAMPS and a novel procedures for the preparation of 8-Br-cAMP, a key starting material.
    Type: Grant
    Filed: June 20, 2005
    Date of Patent: April 10, 2012
    Assignee: Lauras AS
    Inventors: Kjell Undheim, Kjetil Taskén, Jo Klaveness, Geir Langli, Vidar Bjørnstad
  • Process for preparing pharmaceutical compound and intermediates thereof
    Patent number: 8048853
    Abstract: The present invention relates to novel intermediates of formula VII, or an acid addition salt or a solvate thereof, wherein R1 is —(CO)NH2, —CH2NH2 or —CN; R2=R3=H or R2 and R3 together form a cyclic boronate or borate ester; X is a helping group selected from the group consisting of i) a five or six membered heterocyclic aromatic ring and derivatives thereof comprising at least one N-atom being a part of an imine-group, wherein said N-atom forms the point of connection to the cyclohexapeptide ring, and ii) tetrazolyl and derivatives thereof for which a nitrogen atom forms the point of connection to the cyclohexapeptide ring, and a process for the preparation of caspofungin utilizing said intermediates.
    Type: Grant
    Filed: June 13, 2008
    Date of Patent: November 1, 2011
    Assignee: Xellia Pharmaceuticals APS
    Inventors: Audun Heggelund, Ole Heine Kvernenes, Vidar Bjørnstad
  • Process for preparing pharmaceutical compound and intermediates thereof
    Publication number: 20090312541
    Abstract: The present invention relates to novel intermediates of formula VII, or an acid addition salt or a solvate thereof, wherein R1 is —(CO)NH2, —CH2NH2 or —CN; R2?R3?H or R2 and R3 together form a cyclic boronate or borate ester; X is a helping group selected from the group consisting of i) a five or six membered heterocyclic aromatic ring and derivatives thereof comprising at least one N-atom being a part of an imine-group, wherein said N-atom forms the point of connection to the cyclohexapeptide ring, and ii) tetrazolyl and derivatives thereof for which a nitrogen atom forms the point of connection to the cyclohexapeptide ring, and a process for the preparation of caspofungin utilizing said intermediates.
    Type: Application
    Filed: June 13, 2008
    Publication date: December 17, 2009
    Applicant: ALPHARMA APS
    Inventors: Audun Heggelund, Ole Heine Kvernenes, Vidar Bjornstad
  • Purine Nucleotide Derivatives
    Publication number: 20080293665
    Abstract: This invention provides novel 8-carbyl substituted Camps (adenosine 3?,5?-cyclic monophosphorothioate) and a novel procedures for the preparation of 8-Br-cAMP, a key starting material.
    Type: Application
    Filed: June 20, 2005
    Publication date: November 27, 2008
    Applicant: Lauras AS
    Inventors: Kjell Undheim, Kjetil Tasken, Jo Klaveness, Geir Langli, Vidar Bjornstad