Patents by Inventor Viera Kasparcova

Viera Kasparcova has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7622553
    Abstract: The present invention provides rhesus monkey dickkopf-1 (rhDkk-1) and nucleotide sequences encoding it. Also provided herein are recombinant vectors, and recombinant hosts comprising rhDkk-1-encoding nucleotide sequences. Isolated rhDkk-1 can be used to screen and identify novel osteoanabolic compounds that stimulate bone formation for the treatment of osteoporosis or other disorders characterized by insufficient bone mass.
    Type: Grant
    Filed: November 12, 2004
    Date of Patent: November 24, 2009
    Assignee: Merck & Co., Inc.
    Inventors: Shun-ichi Harada, Viera Kasparcova, Helmut Glantschnig
  • Patent number: 7473770
    Abstract: The cynomolgus monkey Dickkopf-4 (cDkk-4) protein, isolated nucleic acid molecules which encode the cDkk-4 protein, and recombinant vectors and hosts comprising DNA encoding the cDkk-4 protein are disclosed. Also disclosed are methods for identifying analytes which interfere with the interaction between the cDkk-4 protein and a homologous or heterologous Dkk receptor and analytes which interfere with the interaction and stimulate bone formation. Analytes identified using the methods are useful for treating osteoporosis and other bone loss disorders.
    Type: Grant
    Filed: November 12, 2004
    Date of Patent: January 6, 2009
    Assignee: Merck & Co., Inc.
    Inventors: Shun-ichi Harada, Viera Kasparcova, Helmut Glantschnig
  • Publication number: 20070111253
    Abstract: The present invention provides rhesus monkey dickkopf-1 (rhDkk-1) and nucleotide sequences encoding it. Also provided herein are recombinant vectors, and recombinant hosts comprising rhDkk-1-encoding nucleotide sequences. Isolated rhDkk-1 can be used to screen and identify novel osteoanabolic compounds that stimulate bone formation for the treatment of osteoporosis or other disorders characterized by insufficient bone mass.
    Type: Application
    Filed: November 12, 2004
    Publication date: May 17, 2007
    Inventors: Shun-ichi Harada, Viera Kasparcova, Helmut Glantsching
  • Publication number: 20070087384
    Abstract: The cynomolgus monkey Dickkopf-4 (cDkk-4) protein, isolated nucleic acid molecules which encode the cDkk-4 protein, and recombinant vectors and hosts comprising DNA encoding the cDkk-4 protein are disclosed. Also disclosed are methods for identifying analytes which interfere with the interaction between the cDkk-4 protein and a homologous or heterologous Dkk receptor and analytes which interfere with the interaction and stimulate bone formation. Analytes identified using the methods are useful for treating osteoporosis and other bone loss disorders.
    Type: Application
    Filed: November 12, 2004
    Publication date: April 19, 2007
    Inventors: Shun-ichi Harada, Viera Kasparcova, Helmut Glantschnig