Patents by Inventor Vigneshwaran NAMASIVAYAM

Vigneshwaran NAMASIVAYAM has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MRGPRX4 Agonists and Antagonists
    Publication number: 20240002416
    Abstract: The invention relates to MRGPRX4 receptor agonists and antagonists useful for treating, alleviating and/or preventing diseases and disorders related to MRGPRX4 receptor function as well as pharmaceutical compositions comprising such compounds and methods for preparing such compounds. The invention is further directed to the use of these compounds, alone or in combination with other therapeutic agents, for alleviating, preventing and/or treating diseases and disorders, especially the use as wound healing medicaments and for the treatment of chronic pain and itch.
    Type: Application
    Filed: October 15, 2021
    Publication date: January 4, 2024
    Inventors: Wessam Alnouri, Jorg Hockemeyer, Daniel Marx, Christa Muller, Vigneshwaran Namasivayam, Yvonne Riedel, Dominik Thimm, Sophie Clemens, Robin Gedschold, Thanigaimalai Pillaiyar
  • Aza (indole)-, benzothiophene-, and benzofuran-3-sulfonamides
    Patent number: 11820746
    Abstract: Disclosed are sulfonamide compounds with GPR17 modulating properties, which are useful for treating or preventing a variety of CNS and other diseases, in particular for preventing and treating myelinating diseases or disorders.
    Type: Grant
    Filed: January 5, 2022
    Date of Patent: November 21, 2023
    Assignee: UCB PHARMA GMBH
    Inventors: Christa E. Mueller, Cécile Pegurier, Michael Louis Robert Deligny, Ali El-Tayeb, Joerg Hockemeyer, Marie Ledecq, Joël Mercier, Larurent Provins, Nader M. Boshta, Sanjay Bhattarai, Vigneshwaran Namasivayam, Mario Funke, Lukas Schwach, Sabrina Gollos, Daniel Von Laufenberg, Anaïs Barré
  • Aza (Indole)-, Benzothiophene-, And Benzofuran-3-Sulfonamides
    Publication number: 20230348384
    Abstract: Disclosed are sulfonamide compounds with GPR17 modulating properties, which are useful for treating or preventing a variety of CNS and other diseases, in particular for preventing and treating myelinating diseases or disorders.
    Type: Application
    Filed: July 7, 2023
    Publication date: November 2, 2023
    Inventors: Christa E. MUELLER, Cécile PEGURIER, Michael Louis Robert DELIGNY, Ali EL-TAYEB, Joerg HOCKEMEYER, Marie LEDECQ, Joël MERCIER, Larurent PROVINS, Nader M. BOSHTA, Sanjay BHATTARAI, Vigneshwaran NAMASIVAYAM, Mario FUNKE, Lukas SCHWACH, Sabrina GOLLOS, Daniel VON LAUFENBERG, Anaïs BARRÉ
  • Aza (indole)-, benzothiophene-, and benzofuran-3-sulfonamides
    Patent number: 11345662
    Abstract: Disclosed are sulfonamide compounds with GPR17 modulating properties, which are useful for treating or preventing a variety of CNS and other diseases, in particular for preventing and treating myelinating diseases or disorders.
    Type: Grant
    Filed: December 27, 2017
    Date of Patent: May 31, 2022
    Assignee: UCB Pharma GmbH
    Inventors: Christa E. Mueller, Cécile Pegurier, Michael Louis Robert Deligny, Ali El-Tayeb, Joerg Hockemeyer, Marie Ledecq, Joël Mercier, Laurent Provins, Nader M. Boshta, Sanjay Bhattarai, Vigneshwaran Namasivayam, Mario Funke, Lukas Schwach, Sabrina Gollos, Daniel Von Laufenberg, Anaïs Barré
  • Aza (Indole)-, Benzothiophene-, And Benzofuran-3-Sulfonamides
    Publication number: 20220127227
    Abstract: Disclosed are sulfonamide compounds with GPR17 modulating properties, which are useful for treating or preventing a variety of CNS and other diseases, in particular for preventing and treating myelinating diseases or disorders.
    Type: Application
    Filed: January 5, 2022
    Publication date: April 28, 2022
    Inventors: Christa E. MUELLER, Cécile PEGURIER, Michael Louis Robert DELIGNY, Ali EL-TAYEB, Joerg HOCKEMEYER, Marie LEDECQ, Joël MERCIER, Larurent PROVINS, Nader M. BOSHTA, Sanjay BHATTARAI, Vigneshwaran NAMASIVAYAM, Mario FUNKE, Lukas SCHWACH, Sabrina GOLLOS, Daniel VON LAUFENBERG, Anaïs BARRÉ
  • Aza (Indole)-, Benzothiophene-, And Benzofuran-3-Sulfonamides
    Publication number: 20220048858
    Abstract: Disclosed are sulfonamide compounds with GPR17 modulating properties, which are useful for treating or preventing a variety of CNS and other diseases, in particular for preventing and treating myelinating diseases or disorders.
    Type: Application
    Filed: October 20, 2021
    Publication date: February 17, 2022
    Inventors: Christa E. MUELLER, Cécile PEGURIER, Michael Louis Robert DELIGNY, Ali EL-TAYEB, Joerg HOCKEMEYER, Marie LEDECQ, Joël MERCIER, Larurent PROVINS, Nader M. BOSHTA, Sanjay BHATTARAI, Vigneshwaran NAMASIVAYAM, Mario FUNKE, Lukas SCHWACH, Sabrina GOLLOS, Daniel Von Laufenberg, Anaïs BARRÉ
  • PURINE AND PYRIMIDINE NUCLEOTIDES AS ECTO-5'-NUCLEOTIDASE INHIBITORS
    Publication number: 20210169911
    Abstract: Disclosed is a compound of formula (I), wherein Q, U, T, A, a, b, c, and n are as defined herein. Also disclosed are methods of inhibiting ecto-5?-nucleotidase, inhibiting suppression of an antitumor immune response, inhibiting tumor growth of a cancerous tumor, inhibiting metastasis of cancer in a mammal afflicted with cancer, synergistically enhancing a response of a mammal afflicted with cancer undergoing treatment with an immunotherapeutic anti-cancer agent, potentiating an activity of an inhibitor of nicotinamide phosphoribosyltransferase in a mammal undergoing treatment of a mammal with the inhibitor, and treating preeclampsia in a mammal in need thereof, comprising administering to an animal an effective amount of a compound of formula (I).
    Type: Application
    Filed: August 16, 2019
    Publication date: June 10, 2021
    Applicants: The United States of America,as represented by the Secretary,Department of Health and Human Services, University of Bonn, University of Münster
    Inventors: Kenneth A. Jacobson, Anna Junker, Mirko Scortichini, Clemens Dobelmann, Christian P. Renn, Vigneshwaran Namasivayam, Riham Mohammed Idris, Christa E. Müller
  • MRGX Receptor Antagonists
    Publication number: 20210128561
    Abstract: The invention relates to a method for preventing or treating a disease or disorder that is associated with the MrgX2 receptor. The invention also relates to MrgX2 antagonists and physiologically acceptable salts thereof. The invention also relates to pharmaceutical compositions and dosage forms comprising an MrgX2 antagonist.
    Type: Application
    Filed: October 31, 2019
    Publication date: May 6, 2021
    Inventors: Christa Müller, Mohamad Wessam Alnouri, Yvonne Riedel, Dominik Thimm, Daniel Marx, Vigneshwaran Namasivayam, Susanne Gattner, Piet Herdewyn, Steven De Jonghe, Piotr Leonczak, Sven Verdonck
  • Aza (Indole)-, Benzothiophene-, And Benzofuran-3-Sulfonamides
    Publication number: 20190345104
    Abstract: Disclosed are sulfonamide compounds with GPR17 modulating properties, which are useful for treating or preventing a variety of CNS and other diseases, in particular for preventing and treating myelinating diseases or disorders.
    Type: Application
    Filed: December 27, 2017
    Publication date: November 14, 2019
    Applicant: UCB Pharma GmbH
    Inventors: Christa E. MUELLER, Cécile PEGURIER, Michael Louis Robert DELIGNY, Ali EL-TAYEB, Joerg HOCKEMEYER, Marie LEDECQ, Joël MERCIER, Laurent PROVINS, Nader M. BOSHTA, Sanjay BHATTARAI, Vigneshwaran NAMASIVAYAM, Mario FUNKE, Lukas SCHWACH, Sabrina GOLLOS, Daniel von LAUFENBERG, Anaïs BARRÉ