Patents by Inventor Vijay Kumar Chaudhary

Vijay Kumar Chaudhary has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antibody fragment library, and uses thereof
    Patent number: 11725306
    Abstract: The present disclosure discloses an antibody fragment library, method for preparing the library and its applications. The essential steps in construction of the library is devoid of any restriction enzyme. Emulsion based PCR has been used as an important tool for the construction and validation of the library. The method as disclosed in the present disclosure leads to construction of a library comprising at least 8 billion clones.
    Type: Grant
    Filed: November 30, 2018
    Date of Patent: August 15, 2023
    Assignee: UNIVERSITY OF DELHI SOUTH CAMPUS
    Inventors: Vijay Kumar Chaudhary, Amita Gupta, Vaishali Verma
  • A PROCESS FOR IMMOBILIZING POLYPEPTIDES
    Publication number: 20200363410
    Abstract: The present disclosure discloses a process for immobilizing polypeptides on a surface, said method comprising: (a) coating a surface with a molecule to capture biotin tagged polypeptide to obtain a coated surface; and (b) contacting at least two biotin tagged polypeptides with the coated surface of step (a) to obtain immobilized polypeptides, wherein the biotin tagged polypeptide comprises a biotin linked to a recombinant polypeptide. The present disclosure further discloses an in-vitro method for detecting at least one binder molecule in a sample, and a process for obtaining biotin tagged polypeptide.
    Type: Application
    Filed: November 8, 2018
    Publication date: November 19, 2020
    Inventors: Vijay Kumar CHAUDHARY, Amita GUPTA, Vaishali VERMA, Charanpreet KAUR, Payal GROVER
  • AN ANTIBODY FRAGMENT LIBRARY, AND USES THEREOF
    Publication number: 20200318100
    Abstract: The present disclosure discloses an antibody fragment library, method for preparing the library and its applications. The essential steps in construction of the library is devoid of any restriction enzyme. Emulsion based PCR has been used as an important tool for the construction and validation of the library. The method as disclosed in the present disclosure leads to construction of a library comprising at least 8 billion clones.
    Type: Application
    Filed: November 30, 2018
    Publication date: October 8, 2020
    Inventors: Vijay Kumar CHAUDHARY, Amita GUPTA, Vaishali VERMA
  • Lambda phage display system and the process
    Patent number: 7410801
    Abstract: The present invention relates to a process of obtaining recombinant lambdoid bacteriophage with high density display of functional peptides and proteins on surface of said phage comprising of: constructing a donor plasmid having a nucleotide sequence that defines the elements for replication of the vector in bacteria, a selectable marker, a nucleotide sequence flanked by two non-compatible recombination sequences, and an inducible cistron for expression of a capsid protein and a fusion protein; constructing a recipient phage having a nucleotide sequence that defines the lambdoid elements for replication and packaging of the vector into an assembled bacteriophage and encodes an inducible cistron for expression of a selectable marker flanked by two non-compatible recombination sequences; transferring the said donor plasmid to said recipient plasmid to obtain cointegrates; growing said cointegrates in selective liquid medium; harvesting phages displaying protein encoded by the foreign DNA encapsulated in said ha
    Type: Grant
    Filed: May 20, 2003
    Date of Patent: August 12, 2008
    Assignee: University of Delhi Department of Biochemistry
    Inventors: Vijay Kumar Chaudhary, Amita Gupta, Sankar Adhya, Ira Pastan
  • Constructs encoding recombinant antibody-toxin fusion proteins
    Patent number: 6051405
    Abstract: The present invention describes constructs encoding recombinant scFv-toxin fusion proteins which selectively kill cells bearing appropriate antigens or receptors.
    Type: Grant
    Filed: April 8, 1992
    Date of Patent: April 18, 2000
    Assignees: The United States of America as represented by the Secretary of the Department of Health and Human Services, Protein Design Labs, Inc.
    Inventors: David FitzGerald, Vijay Kumar Chaudhary, Ira Harry Pastan, Thomas Alexander Waldmann, Cary L Queen
  • Recombinant antibody-toxin fusion protein
    Patent number: 5863745
    Abstract: The present invention describes recombinant antibody toxin fusion proteins which selectively kill cells bearing appropriate antigens or receptors.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: January 26, 1999
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: David J. Fitzgerald, Vijay Kumar Chaudhary, Ira H. Pastan, Thomas Alexander Waldmann, Cary L. Queen
  • Recombinant antibody-toxin fusion protein
    Patent number: 5696237
    Abstract: The present invention describes recombinant antibody toxin fusion proteins which selectively kill cells bearing appropriate antigens or receptors.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: December 9, 1997
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: David FitzGerald, Vijay Kumar Chaudhary, Ira Harry Pastan, Thomas Alexander Waldmann, Cary L. Queen