Patents by Inventor Vijay Prem Singh

Vijay Prem Singh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • GASTRODUODENAL BALLOON TUBES AND METHODS FOR USE IN LOCALIZED HYPOTHERMIA
    Publication number: 20240268996
    Abstract: Materials and methods for producing localized hypothermia in a patient (e.g., for treatment of acute pancreatitis and pancreatic cancer).
    Type: Application
    Filed: April 1, 2024
    Publication date: August 15, 2024
    Inventor: Vijay Prem SINGH
  • Lipase inhibitors for the treatment of pancreatitis and organ failure
    Patent number: 9943499
    Abstract: The present invention relates to methods for treating pancreatitis and/or organ failure comprising administering, to a subject in need of such treatment, an effective amount of a lipase inhibitor. It is based, at least in part, on the discoveries that lipotoxicity contributes to inflammation, multisystem organ failure, necrotic pancreatic acinar cell death and in acute pancreatitis, and that inhibition of lipolysis was able to reduce indices associated with these conditions. Accordingly, in various embodiments, the present invention provides for methods and compositions for limiting lipotoxicity and thereby reducing the likelihood of poor outcomes associated with acute pancreatitis and other severe systemic conditions, especially in obese individuals.
    Type: Grant
    Filed: April 2, 2015
    Date of Patent: April 17, 2018
    Assignee: University of Pittsburgh—of the Commonwealth System of Higher Education
    Inventor: Vijay Prem Singh
  • Lipase inhibitors for the treatment of pancreatitis and organ failure
    Patent number: 9023887
    Abstract: The present invention relates to methods for treating pancreatitis and/or organ failure comprising administering, to a subject in need of such treatment, an effective amount of a lipase inhibitor. It is based, at least in part, on the discoveries that lipotoxicity contributes to inflammation, multisystem organ failure, necrotic pancreatic acinar cell death and in acute pancreatitis, and that inhibition of lipolysis was able to reduce indices associated with these conditions. Accordingly, in various embodiments, the present invention provides for methods and compositions for limiting lipotoxicity and thereby reducing the likelihood of poor outcomes associated with acute pancreatitis and other severe systemic conditions, especially in obese individuals.
    Type: Grant
    Filed: April 16, 2012
    Date of Patent: May 5, 2015
    Assignee: University of Pittsburgh—of the Commonwealth System of Higher Education
    Inventor: Vijay Prem Singh
  • Lipase Inhibitors for the Treatment of Pancreatitis and Organ Failure
    Publication number: 20120289588
    Abstract: The present invention relates to methods for treating pancreatitis and/or organ failure comprising administering, to a subject in need of such treatment, an effective amount of a lipase inhibitor. It is based, at least in part, on the discoveries that lipotoxicity contributes to inflammation, multisystem organ failure, necrotic pancreatic acinar cell death and in acute pancreatitis, and that inhibition of lipolysis was able to reduce indices associated with these conditions. Accordingly, in various embodiments, the present invention provides for methods and compositions for limiting lipotoxicity and thereby reducing the likelihood of poor outcomes associated with acute pancreatitis and other severe systemic conditions, especially in obese individuals.
    Type: Application
    Filed: April 16, 2012
    Publication date: November 15, 2012
    Inventor: Vijay Prem Singh