Abstract: The present invention discloses a Plectin-1 receptor targeting novel cationic KTLLPTPK(SEQ ID NO: 1)-lipopeptide. The present invention further discloses a liposomal formulation comprising the cationic KTLLPTPK(SEQ ID NO: 1)-lipopeptide, at least two co-lipids, a therapeutic agent, and a pharmaceutically acceptable carrier. The present invention also provides a method for regressing established pancreatic tumors comprising administering a therapeutically effective amount of the liposomal formulation with the therapeutic agents in combination with targeted genetic immunization (DNA vaccination) i.e. by immunizing mice with electrostatic complexes (direct in-vivo DC-targeting cationic liposomes) of DNA vaccines encoding mesothelin (p-CMV-MSLN).

Abstract: A method includes receiving from a networked spoke device information describing network flows to and from an application, analyzing the information to characterize the application in at least one dimension selected from the group consisting of bi-directional bandwidth usage, network response times, application response times, a number of idle and active application sessions and a maximum number of concurrent application sessions and transmitting the dimensions to at least one networked spoke device as traffic profile information.

Abstract: A method includes determining a network requirement for at least one application, dynamically determining a link suitable for data transmission in accordance with a policy based at least in part on a current network condition to meet the network requirement and routing one or more application network data flows associated with the at least one application over the link.

Abstract: The present invention discloses a Plectin-1 receptor targeting novel cationic KTLLPTPK-lipopeptide. The present invention further discloses a liposomal formulation comprising the cationic KTLLPTPK-lipopeptide, at least two co-lipids, therapeutic agents and a pharmaceutically acceptable carrier. The present invention also provides a method for regressing established pancreatic tumors comprising administering therapeutically effective amount of the liposomal formulation with the therapeutic agents in combination with targeted genetic immunization (DNA vaccination) i.e. by immunizing mice with electrostatic complexes (direct in-vivo DC-targeting cationic liposomes) of DNA vaccines encoding mesothelin (p-CMV-MSLN).

Abstract: A method includes determining a network requirement for at least one application, dynamically determining a link suitable for data transmission in accordance with a policy based at least in part on a current network condition to meet the network requirement and routing one or more application network data flows associated with the at least one application over the link.

Abstract: A method includes receiving from a networked spoke device information describing network flows to and from an application, analyzing the information to characterize the application in at least one dimension selected from the group consisting of bi-directional bandwidth usage, network response times, application response times, a number of idle and active application sessions and a maximum number of concurrent application sessions and transmitting the dimensions to at least one networked spoke device as traffic profile information.

Abstract: Various embodiments for hyper-channel management are disclosed. One such method is implemented by a network interface controller (NIC) residing in a server. This method involves determining a network component that is operable to create, modify, terminate, or any combination thereof, a hyper-channel. The hyper-channel corresponds to a logical abstraction of network resources associated with the server. The method also involves using the determined network component to manage the hyper-channel.

Abstract: Techniques for building and managing network policies for accessing resources of a datacenter are described herein. In one embodiment, events are captured within a network element pertaining to certain activities of accessing certain resources of a datacenter, wherein the network element operates as an application service gateway to the datacenter. A new rule/policy is provisioned based on attributes extracted from the captured events, where the attributes includes at least one of user attribute, environment attribute, and a resource attribute. A simulation is performed on the new rule/policy under a real time network traffic condition, generating a simulation result. The new rule/policy is committed if the simulation result satisfies a predetermined condition, wherein the new rule/policy is enforced within the network element to determine whether a particular client is eligible to access a particular resource of the datacenter. Other methods and apparatuses are also described.

Abstract: A server comprising a network interface controller (NIC) may be operable to determine network components and/or resources that may be utilized to create, modify and/or terminate a hyper-channel in a network fabric. A configuration for creating, modifying and/or terminating the hyper-channel may be initiated by the NIC based on knowledge of the network fabric up to the edge of network and each of the switches along a path of the hyper-channel may be instructed by the NIC to configure the hyper-channel. The configuration may also be initiated by the NIC based on knowledge of the network fabric up to a first hop and each of the switches along a path of the hyper-channel may then be allowed to configure the hyper-channel based on knowledge of the network fabric surrounding each of the switches.

Abstract: A server comprising a network interface controller (NIC) may be operable to determine network components and/or resources that may be utilized to create, modify and/or terminate a hyper-channel in a network fabric. A configuration for creating, modifying and/or terminating the hyper-channel may be initiated by the NIC based on knowledge of the network fabric up to the edge of network and each of the switches along a path of the hyper-channel may be instructed by the NIC to configure the hyper-channel. The configuration may also be initiated by the NIC based on knowledge of the network fabric up to a first hop and each of the switches along a path of the hyper-channel may then be allowed to configure the hyper-channel based on knowledge of the network fabric surrounding each of the switches.

Abstract: Techniques for building and managing network policies for accessing resources of a datacenter are described herein. In one embodiment, events are captured within a network element pertaining to certain activities of accessing certain resources of a datacenter, wherein the network element operates as an application service gateway to the datacenter. A new rule/policy is provisioned based on attributes extracted from the captured events, where the attributes includes at least one of user attribute, environment attribute, and a resource attribute. A simulation is performed on the new rule/policy under a real time network traffic condition, generating a simulation result. The new rule/policy is committed if the simulation result satisfies a predetermined condition, wherein the new rule/policy is enforced within the network element to determine whether a particular client is eligible to access a particular resource of the datacenter. Other methods and apparatuses are also described.