Abstract: A framework for multi-scan image processing. A single real anatomic image of a region of interest is first acquired. One or more emission images of the region of interest are also acquired. One or more synthetic anatomic images may be generated based on the one or more emission images. One or more deformable registrations of the real anatomic image to the one or more synthetic anatomic images are performed to generate one or more registered anatomic images. Attenuation correction may then be performed on the one or more emission images using the one or more registered anatomic images to generate one or more attenuation corrected emission images.

Abstract: Systems and methods are provided for quantifying and monitoring liver disease in a patient from voltage-time data. A method comprises receiving voltage-time data of a subject, the voltage-time data comprising voltage data of a plurality of leads of an electrocardiograph; generating a feature vector from the voltage-time data; providing the feature vector to a pretrained learning system; receiving from the pretrained learning system a status of liver disease in the subject.

Abstract: A system and method include acquisition of positron emission tomography data of an object while a radiation source moves within the object, determination of a plurality of locations within the object, each of the plurality of locations associated with a respective time at which the radiation source was located at the location, determination of a respective time period associated with each of the plurality of locations, determination, for each of the determined time periods, of a frame of the positron emission tomography data associated with the determined time period, and, for each frame of the positron emission tomography data, generation of an image based on the frame and on the location associated with the time period associated with the frame.

Abstract: An implantable prosthesis for mending anatomical defects, including a groin hernia. The prosthesis includes a prosthetic repair patch that may be implanted in different tissue planes to mend a defect. The patch may include a medial portion configured to be positioned in a first tissue plane and a lateral portion configured to be positioned in a second tissue plane offset from the first tissue plane. The patch may include a transition region configured to extend through tissue and/or muscle, such as fascia, separating the tissue planes and transition the patch from one tissue plane to the other tissue plane. The transition region may be configured to inhibit buckling and/or bunching of the patch when implanted through the fascia. The lateral portion of the patch may have a level of stiffness that facilitates implantation of the patch in different tissue planes while inhibiting patient sensation to the implanted patch.

Abstract: An implantable prosthesis for mending anatomical defects, including a groin hernia. The prosthesis includes a prosthetic repair patch that may be implanted in different tissue planes to mend a defect. The patch may include a medial portion configured to be positioned in a first tissue plane and a lateral portion configured to be positioned in a second tissue plane offset from the first tissue plane. The patch may include a transition region configured to extend through tissue and/or muscle, such as fascia, separating the tissue planes and transition the patch from one tissue plane to the other tissue plane. The transition region may be configured to inhibit buckling and/or bunching of the patch when implanted through the fascia. The lateral portion of the patch may have a level of stiffness that facilitates implantation of the patch in different tissue planes while inhibiting patient sensation to the implanted patch.

Abstract: A framework for multi-scan image processing. A single real anatomic image of a region of interest is first acquired. One or more emission images of the region of interest are also acquired. One or more synthetic anatomic images may be generated based on the one or more emission images. One or more deformable registrations of the real anatomic image to the one or more synthetic anatomic images are performed to generate one or more registered anatomic images. Attenuation correction may then be performed on the one or more emission images using the one or more registered anatomic images to generate one or more attenuation corrected emission images.

Abstract: The present disclosure relates to a method of integration and compensation in a protection relay. The method may include the protection relay: receiving a measured signal from a Rogowski coil and converting the measured signal to digitized samples, where the measured signal is a differentiated current signal over time; iteratively computing integrated current data from the digitized samples using a first digitized function to obtain integrated value; iteratively computing a compensated current data from the integrated current data using a second digitized function to remove a DC component in the integrated current data; evaluating the compensated current data to identify a fault condition; generating a trip signal on identification of a fault condition to operate a switch to electrically disconnect to protect the power equipment. The steps of integration and compensation may be performed in time window that is within the time period of the measured signal.

Abstract: Methods and systems of revising image models for nuclear imaging are disclosed. A system receives first patient scan data corresponding to one or more nuclear imaging scans performed on one or more individuals and generates a first reconstructed image by applying a first image model to the first patient scan data. Feedback is received regarding the first reconstructed image and the feedback is provided as an input to a deep-reinforcement learning process. The deep-reinforcement learning process is configured to generate at least one modification for the first image model based on the feedback regarding the first reconstructed image. A second image model is generated by applying the at least one modification generated by the deep-reinforcement learning process to the first image model.

Abstract: A system and method include acquisition of positron emission tomography data of an object while a radiation source moves within the object, determination of a plurality of locations within the object, each of the plurality of locations associated with a respective time at which the radiation source was located at the location, determination of a respective time period associated with each of the plurality of locations, determination, for each of the determined time periods, of a frame of the positron emission tomography data associated with the determined time period, and, for each frame of the positron emission tomography data, generation of an image based on the frame and on the location associated with the time period associated with the frame.

Abstract: A system and method include identification of a blood pool region of the body based on the acquired positron emission tomography data, determination of activity in the blood pool region associated with a first time based on the acquired positron emission tomography data, determination of a scale factor based on the determined activity in the blood pool region and on an input function associated with one or more other human bodies, determination of activity in a tissue region associated with a second time based on the acquired positron emission tomography data, determination of a specific uptake ratio associated with the second time based on the activity in the tissue region, the scale factor and a value of the input function at the second time, determination of an estimate of metabolic rate in the tissue region based on the specific uptake ratio and the input function, and determination of a diagnosis associated with the tissue region based on the estimate of metabolic rate.

Abstract: A prosthesis and a method of plugging or covering a trocar tract with the prosthesis is disclosed. The prosthesis includes a tubular body having a proximal end and a distal end, a respective opening at each end, and a channel extending between the proximal end of the tubular body and the distal end of the tubular body. The prosthesis is removably mounted along a trocar. The trocar is removable from the prosthesis such that the prosthesis is left at the trocar tract when the trocar is removed from the tract. The prosthesis includes a delivery configuration and a deployed configuration. In the deployed configuration, the opening at the distal end of the tubular body is smaller than the opening at the proximal end of the tubular body.

Abstract: A method of conducting a multi-pass dynamic positron emission tomography (PET) scans using continuous bed motion (CBM) mode is disclosed where the method involves acquiring PET sinogram data using CBM mode as the patient bed is moving in a first direction; acquiring PET sonogram data using CBM mode as the patient bed is moving in a second direction that is opposite from the first direction; and reconstructing 3-D PET image from the acquired PET sonogram data.

Abstract: Surgical devices for use with robotic surgical systems and their methods of use are described. In some embodiments, the surgical device may include an actuator that interfaces with an end effector of an arm of a robotic surgical system. An output from the end effector may actuate the actuator to perform an operation of the surgical device. In some embodiments, the surgical device may include a retainer that retains at least a portion of the surgical device on a distal portion of the arm of the robotic surgical system during actuation. In other embodiments, the surgical device may include a portion that is engaged by a second robotic surgical arm to hold at least a portion of the surgical device stationary relative to the robotic surgical arm engaged with the actuator of the surgical device.

Abstract: Methods for protecting a peritoneum or other tissue during a surgical procedure are disclosed. In some embodiments, a protective lining is applied to the peritoneum or other tissue before an active surgical intervention, such as before tissue dissection, tissue approximation, and/or other surgical act. In some embodiments, the protective lining includes a protective film applied to the peritoneum or other tissue via a delivery balloon or via a spray instrument.

Abstract: A reductant impingement device includes a proximal end having an impingement pin with a convex surface; and a distal end having a body concentric with a longitudinal axis of the impingement pin. The distal end includes a first surface and a second surface opposite the first surface. A plurality of inner channels connects the first surface and the second surface, and a plurality of outer channels connects the first surface and the second surface, where the plurality of inner channels are disposed in a circular array at a first radial distance from a longitudinal axis of the impingement pin, and the plurality of outer channels are disposed in a circular array at a second distance from the longitudinal axis of the impingement pin.

Abstract: A method for reconstructing medical images comprises: identifying a plurality of organs in a body of a subject based on an anatomic image; assigning a plurality of voxels in the body to respective ones of the plurality of organs based on the anatomic image; and reconstructing activity images of the body using respectively different processing for the voxels assigned to each respective one of the plurality of organs.

Abstract: Articles and methods involving soft tissue repair implants comprising 2-hydroxybutyrate, 3-hydroxybutyrate, 4-hydroxybutyrate, and/or their conjugate acids are generally provided. The 2-hydroxybutyrate, 3-hydroxybutyrate, 4-hydroxybutyrate, and/or the conjugate acid(s) of 2-hydroxybutyrate, 3-hydroxybutyrate, and 4-hydroxybutyrate may be provided in a therapeutically-effective amount for reducing or preventing microbial infection.

Abstract: A method of processing and reconstructing dynamic positron emission tomography (PET) sinogram data comprises: acquiring PET sinogram data using continuous bed motion having a varying velocity; recording a plurality of position-time coordinate pairs while acquiring the PET sinogram data; determining respective acquisition times of each of a plurality of slices of the image, based on the plurality of position-time coordinates; and reconstructing respective parametric images for each respective slice in the plurality of slices.

Abstract: A nozzle including a nozzle body having a proximal end and a distal end. The proximal end includes at least a first inlet and a second inlet, and the distal end includes an outlet. An inner tube extends in a direction along a central longitudinal axis of the nozzle and at least partly defines a first channel fluidly connected to the first inlet and a second channel fluidly connected to the second inlet. The second channel fluidly connects to the first channel via one or more orifices extending through the inner tube.

Abstract: A reductant impingement device includes a proximal end having an impingement pin with a convex surface; and a distal end having a body concentric with a longitudinal axis of the impingement pin. The distal end includes a first surface and a second surface opposite the first surface. A plurality of inner channels connects the first surface and the second surface, and a plurality of outer channels connects the first surface and the second surface, where the plurality of inner channels are disposed in a circular array at a first radial distance from a longitudinal axis of the impingement pin, and the plurality of outer channels are disposed in a circular array at a second distance from the longitudinal axis of the impingement pin.