Patents by Inventor Viji SITTHER

Viji SITTHER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12331336
    Abstract: A recombinant strain of F. diplosiphon was made by transforming wild type F. diplosiphon with a pGEM-7Zf (+) plasmid containing the photolyase gene (phrA) via electroporation. The recombinant strain was designated B481-ViAnSa and overexpressed the phrA gene to result in enhanced UV tolerance compared to wild type F. diplosiphon.
    Type: Grant
    Filed: August 19, 2022
    Date of Patent: June 17, 2025
    Assignee: Morgan State University
    Inventors: Viji Sitther, Samson Gichuki
  • Publication number: 20240352404
    Abstract: Compositions including metal nano-and/or micro-particles in solution with photosynthetic bioproduct producing microorganisms. These light harvesting complexes increase growth rates and photosynthetic efficiency of the constituent microorganisms, reducing the light required for a specific production level, or increases production for a specific light level. Compositions including zero-valent iron nanoparticles (nZVIs) in solution with photosynthetic bioproduct producing microorganisms. The nZVIs cause increased growth, lipid production and fatty acid production.
    Type: Application
    Filed: June 28, 2024
    Publication date: October 24, 2024
    Inventors: Viji Sitther, Somayeh Fathabad
  • Publication number: 20240327882
    Abstract: Methods and compositions are detailed for increasing bio-products in cyanobacteria where the cyanobacteria is incubated in the presence of non-lethal amounts of antibiotic. Non-lethal doses of antibiotic weaken the cell membrane facilitating migration of fatty acids from the cell, reducing inhibition feedback, leading to an increase in bio-products.
    Type: Application
    Filed: March 1, 2024
    Publication date: October 3, 2024
    Inventors: Viji Sitther, Yavuz Yalcin, Busra Aydin
  • Publication number: 20240309407
    Abstract: Methods and compositions for increasing lipid production in cyanobacteria where the cyanobacteria is incubated in the presence of non-lethal amounts of antibiotic. Non-lethal doses of antibiotic weakens the cell membrane facilitating migration of fatty acids from the cell, reducing inhibition feedback of fatty acid precursor enzymes, leading to an increase in fatty acid production.
    Type: Application
    Filed: February 1, 2024
    Publication date: September 19, 2024
    Inventors: Viji Sitther, Yavuz Yalcin, Busra Aydin
  • Patent number: 12024704
    Abstract: Compositions including metal nano- and/or micro-particles in solution with photosynthetic bioproduct producing microorganisms. These light harvesting complexes increase growth rates and photosynthetic efficiency of the constituent microorganisms, reducing the light required for a specific production level, or increases production for a specific light level. Compositions including zero-valent iron nanoparticles (nZVIs) in solution with photosynthetic bioproduct producing microorganisms. The nZVIs cause increased growth, lipid production and fatty acid production.
    Type: Grant
    Filed: December 12, 2019
    Date of Patent: July 2, 2024
    Assignee: Morgan State University
    Inventors: Viji Sitther, Somayeh Fathabad
  • Publication number: 20240099333
    Abstract: A method for improving aquaculture growth and/or survival rate and hemocyte viability, comprising growing the aquaculture in the presence of cyanobacteria F. diplosiphon. The aquaculture may be a shellfish aquaculture, for example, shrimp, crayfish, oysters, clams, mussels, and crabs or combinations thereof. The aquaculture may be freshwater aquaculture, brackish aquaculture, or saltwater aquaculture. The F. diplosiphon may be a wild-type or an engineered/recombinant strain. The F. diplosiphon may be preferably added to aquacultures in amounts of 1 million colony forming units or more per ml of aquaculture volume.
    Type: Application
    Filed: September 22, 2023
    Publication date: March 28, 2024
    Inventors: Ingrid Tulloch, Viji Sitther
  • Publication number: 20230392181
    Abstract: Zero-valent iron nanoparticle-mediated oxidative stress was evaluated in F. diplosiphon as a measure of lipid peroxidation using malondialdehyde and thiobarbituric acid-reactivity (MDA-TBA) assay and the 2?,7?-dichlorodihydrofluorescein diacetate (DCFH-DA) fluorogenic probe. Enzymatic response of nZVI-treated cultures was determined as a measure of FeSOD (iron superoxide dismutase) using western blotting and immunodetection. In addition, the distribution and surface assimilation of nZVIs was detected using transmission electron microscopy (TEM) and energy-dispersive X-ray spectroscopy (EDS).
    Type: Application
    Filed: June 5, 2023
    Publication date: December 7, 2023
    Inventors: Viji Sitther, Samson Gichuki
  • Publication number: 20230340502
    Abstract: A recombinant strain of F. diplosiphon was made by transforming wild type F. diplosiphon with a pGEM-7Zf (+) plasmid containing the photolyase gene (phrA) via electroporation. The recombinant strain was designated B481-ViAnSa and overexpressed the phrA gene to result in enhanced UV tolerance compared to wild type F. diplosiphon.
    Type: Application
    Filed: August 19, 2022
    Publication date: October 26, 2023
    Inventors: Viji Sitther, Samson Gichuki
  • Patent number: 11162067
    Abstract: Compositions including metal nano- and/or micro-particles in solution with photosynthetic bioproduct producing microorganisms. These light harvesting complexes increase growth rates and photosynthetic efficiency of the constituent microorganisms, reducing the light required for a specific production level, or increases production for a specific light level.
    Type: Grant
    Filed: August 16, 2017
    Date of Patent: November 2, 2021
    Assignee: Morgan State University
    Inventors: Viji Sitther, Kadir Aslan, Behnam Tabatabai
  • Patent number: 10793883
    Abstract: A recombinant strain of F. diplosiphon was made by transforming wild type F. diplosiphon with a pGEM-7Zf (+) plasmid containing sterol desaturase gene (SD) via electroporation. The recombinant strain was designated B481-SD and overexpressed the sterol desaturase gene to result in enhanced lipid production. Selection made on NaCl enabled growth of the transformant to thrive up to 50 g L?1 NaCl. This strain was designated B481-SDH.
    Type: Grant
    Filed: September 6, 2018
    Date of Patent: October 6, 2020
    Assignee: Morgan State University
    Inventors: Viji Sitther, Somayeh Gharaie Fathabad
  • Publication number: 20200131469
    Abstract: Compositions including metal nano- and/or micro-particles in solution with photosynthetic bioproduct producing microorganisms. These light harvesting complexes increase growth rates and photosynthetic efficiency of the constituent microorganisms, reducing the light required for a specific production level, or increases production for a specific light level. Compositions including zero-valent iron nanoparticles (nZVIs) in solution with photosynthetic bioproduct producing microorganisms. The nZVIs cause increased growth, lipid production and fatty acid production.
    Type: Application
    Filed: December 12, 2019
    Publication date: April 30, 2020
    Inventors: Viji Sitther, Somayeh Fathabad
  • Patent number: 10626363
    Abstract: The present invention relates to a recombinant cyanobacterium with enhanced halotolerance and compositions thereof, methods of producing the recombinant cyanobacterium, and methods of using the same for biofuel production. The invention also relates to transformed F. diplosiphon strains with enhanced salt tolerance.
    Type: Grant
    Filed: December 6, 2017
    Date of Patent: April 21, 2020
    Assignee: Morgan State University
    Inventors: Viji Sitther, Behnam Tabatabai
  • Publication number: 20190071699
    Abstract: A recombinant strain of F. diplosiphon was made by transforming wild type F. diplosiphon with a pGEM-7Zf (+) plasmid containing sterol desaturase gene (SD) via electroporation. The recombinant strain was designated B481-SD and overexpressed the sterol desaturase gene to result in enhanced lipid production. Selection made on NaCl enabled growth of the transformant to thrive up to 50 g L?1 NaCl. This strain was designated B481-SDH.
    Type: Application
    Filed: September 6, 2018
    Publication date: March 7, 2019
    Inventors: Viji Sitther, Somayeh Gharaie Fathabad
  • Publication number: 20180291332
    Abstract: The present invention relates to a recombinant cyanobacterium with enhanced halotolerance and compositions thereof, methods of producing the recombinant cyanobacterium, and methods of using the same for biofuel production. The invention also relates to transformed F. diplosiphon strains with enhanced salt tolerance.
    Type: Application
    Filed: December 6, 2017
    Publication date: October 11, 2018
    Applicant: Morgan State University
    Inventors: Viji Sitther, Behnam Tabatabai
  • Publication number: 20180051246
    Abstract: Compositions including metal nano- and/or micro-particles in solution with photosynthetic bioproduct producing microorganisms. These light harvesting complexes increase growth rates and photosynthetic efficiency of the constituent microorganisms, reducing the light required for a specific production level, or increases production for a specific light level.
    Type: Application
    Filed: August 16, 2017
    Publication date: February 22, 2018
    Inventors: Viji Sitther, Kadir Aslan
  • Publication number: 20160097029
    Abstract: The present invention relates to a recombinant cyanobacterium with enhanced halotolerance and compositions thereof, methods of producing the recombinant cyanobacterium, and methods of using the same for biofuel production. The invention also relates to transformed F. diplosiphon strains with enhanced salt tolerance.
    Type: Application
    Filed: October 2, 2015
    Publication date: April 7, 2016
    Applicant: MORGAN STATE UNIVERSITY
    Inventors: Viji SITTHER, Behnam Tabatabai