Abstract: Aspects of data management are described. Information for updating a cluster of storage nodes to a second version may be obtained. Based on obtaining the information, a cluster-level precheck procedure may be performed prior to initiating an update procedure for the cluster of storage nodes. Also, during the update procedure, a node-level precheck procedure may be performed prior to initiating an update of a storage node to determine whether the storage node is in a state for successful update. Based on a result of the node-level precheck, a determination of whether to delay the update of the storage node may be made.

Abstract: The present invention relates to pharmaceutical composition comprising dimethyl fumarate; an enzyme modulator or a permeation enhancer or both; and one or more pharmaceutically acceptable excipients. It further relates to a pulsatile release pharmaceutical composition comprising dimethyl fumarate and one or more pharmaceutically acceptable excipients. The compositions of the present invention are administered at a lower dose as compared to the recommended daily dose of Tecfidera®. Further, the compositions of the present invention are resistant to dose dumping in the presence of alcohol.

Abstract: The present invention relates to high dose oral pharmaceutical compositions of artemether and lumefantrine, and process for preparation thereof. The compositions comprise of artemether and lumefantrine comprising artemether in an amount of from about 40 mg to about 80 mg, lumefantrine in an amount of from about 240 mg to about 480 mg. The compositions are useful for treatment of uncomplicated infections with Plasmodium falciparum, including strains from multi-drug-resistant areas.