Patents by Inventor Vikas Bhandari

Vikas Bhandari has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • STABLE LIQUID COMPOSITIONS OF PEMETREXED
    Publication number: 20220151923
    Abstract: The present invention relates to a stable liquid pharmaceutical composition of pemetrexed for parenteral administration. The invention provides composition comprising pemetrexed diacid, an organic amine and cyclodextrin. The composition may further comprise an inert gas. The composition can be ready to use infusion solution of pemetrexed diacid or liquid concentrate formulation to be diluted before administration to the patient. The present invention further relates to a process for manufacturing the compositions as well as use of the compositions of the invention for the treatment of malignant pleural mesothelioma and non-small cell lung cancer.
    Type: Application
    Filed: September 27, 2021
    Publication date: May 19, 2022
    Applicant: FRESENIUS KABI ONCOLOGY LIMITED
    Inventors: Dhiraj KHATTAR, Rajesh KHANNA, Abhilasha YADAV, Vikas BHANDARI, Sameer Ramanlal MODI, . HEMLATA
  • STABLE LIQUID COMPOSITIONS OF PEMETREXED
    Publication number: 20200246263
    Abstract: The present invention relates to a stable liquid pharmaceutical composition of pemetrexed for parenteral administration. The invention provides composition comprising pemetrexed diacid, an organic amine and cyclodextrin. The composition may further comprise an inert gas. The composition can be ready to use infusion solution of pemetrexed diacid or liquid concentrate formulation to be diluted before administration to the patient. The present invention further relates to a process for manufacturing the compositions as well as use of the compositions of the invention for the treatment of malignant pleural mesothelioma and non-small cell lung cancer.
    Type: Application
    Filed: August 28, 2018
    Publication date: August 6, 2020
    Applicant: FRESENIUS KABI ONCOLOGY LIMITED
    Inventors: Dhiraj KHATTAR, Rajesh KHANNA, Abhilasha YADAV, Vikas BHANDARI, Sameer Ramanlal MODI, Hemlata
  • Process for preparing stable pharmaceutical compositions of compounds susceptible to hydrolysis
    Patent number: 9872873
    Abstract: The present invention relates to a process of preparing a stable pharmaceutical composition of compounds which are susceptible to hydrolysis comprising a. Addition of required quantity of pharmaceutically acceptable lyophilization excipients optionally in Water for Injection in a formulation vessel; b. Addition of organic solvent to form a appropriate proportion of aqueous and organic solvent; c. Maintaining the temperature of the formulation vessel from the range ?5±1° C. to ?5±3° C.; d. Addition of required quantity of compound susceptible to hydrolysis to form a solution and lyophilizing the solution.
    Type: Grant
    Filed: March 29, 2012
    Date of Patent: January 23, 2018
    Assignee: Fresenius Kabi Oncology Limited
    Inventors: Dhiraj Khattar, Rajesh Khanna, Sanjay Motwani, Minakshi Garg, Vikas Chandel, Mukti Yadav, Vijay Kumar Kyama, Vikas Bhandari
  • PROCESS FOR PREPARING STABLE PHARMACEUTICAL COMPOSITIONS OF COMPOUNDS SUSCEPTIBLE TO HYDROLYSIS
    Publication number: 20140378407
    Abstract: The present invention relates to a process of preparing a stable pharmaceutical composition of compounds which are susceptible to hydrolysis comprising a. Addition of required quantity of pharmaceutically acceptable lyophilization excipients optionally in Water for Injection in a formulation vessel; b. Addition of organic solvent to form a appropriate proportion of aqueous and organic solvent; c. Maintaining the temperature of the formulation vessel from the range ?5±1° C. to ?5±3° C.; d. Addition of required quantity of compound susceptible to hydrolysis to form a solution and lyophilizing the solution.
    Type: Application
    Filed: March 29, 2012
    Publication date: December 25, 2014
    Applicant: Fresenius Kabi Oncology Limited
    Inventors: Dhiraj Khattar, Rajesh Khanna, Sanjay Motwani, Minakshi Garg, Vikas Chandel, Mukti Yadav, Vijay Kumar Kyama, Vikas Bhandari