Patents by Inventor Vikram Bhardwaj

Vikram Bhardwaj has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Synergistic hepatoprotective composition and a method thereof
    Patent number: 7794753
    Abstract: The present invention relates to a synergistic formulation comprising trans-tetracos-15-enoic acid (t-TCA) and andrographolide (AP) in the ratio ranging between 1:7 to 7:1 (w/w), useful in hepatoprotection; and a process for the preparation of a synergistic formulation comprising trans-tetracos-15-enoic acid (t-TCA) and andrographolide (AP) useful in hepatoprotection, said process comprising steps of grounding the particles of the t-TCA and AP into fine particles, mixing the fine particles in ratio ranging between 1:7 to 7:1 (w/w), and grinding the mixture to obtain formulation, and also, a method of hepatoprotection of a subject using the synergistic formulation comprising trans-tetracos-15-enoic acid (t-TCA) and andrographolide (AP), said method comprising the steps of administering the formulation to the subject.
    Type: Grant
    Filed: March 31, 2003
    Date of Patent: September 14, 2010
    Assignee: Council of Scientific and Industrial Research
    Inventors: Vishwa Nath Gupta, Krishan Avtar Suri, Bishan Datt Gupta, Bupinder Singh Jaggi, Naresh Kumar Satti, Bal Krishan Chandan, Neelam Sharma, Vikram Bhardwaj, Om Parkash Suri, Ghulam Nabi Qazi, Jyotsna Suri, Madalsa Bargotra
  • Pharmaceutical composition and process for isolation of trans-tetracos-15-enoic acid and method of treatment for hepatotoxicity
    Patent number: 7118766
    Abstract: The present invention relates to a pharmaceutical composition comprising a bioactive constituent trans-tetracos-15-enoic acid and a process for the isolation of tetracos-15-enoic acid from the plant Indigofera tinctoria along with a method of treatment for hepatotoxicity.
    Type: Grant
    Filed: February 11, 2002
    Date of Patent: October 10, 2006
    Assignee: Council of Scientific & Industrial Research
    Inventors: Sukhdev Swami Handa, Bupinder Singh, Bal Krishan Chandan, Ajit Kumar Saxena, Vikram Bhardwaj, V. N. Gupta, Om Parkash Suri, Naresh Kumar Satti, Krishan Avtar Suri
  • Synergistic composition of trans-tetracos-15-enoic acid and Apocynin and method of treatment for hepatotoxicity
    Patent number: 6949586
    Abstract: The present invention relates to a synergistic hepatoprotective pharmaceutical composition comprising an effective amount of trans-tetracos-15-enoic acid (TCA) and Apocynin (APO), the present invention also relates to a method of treatment for hepatotoxicity in mammals and humans.
    Type: Grant
    Filed: March 20, 2002
    Date of Patent: September 27, 2005
    Assignee: Council of Scientific Research
    Inventors: Sukhdev Swami Handa, Om Parkash Suri, Vishwa Nath Gupta, Krishan Avtar Suri, Naresh Kumar Satti, Vikram Bhardwaj, Bupinder Singh, Bal Krishan Chandan
  • Process for the synthesis of trans-alkenoic acids, use thereof
    Patent number: 6852759
    Abstract: The present invention relates to a process for the preparation of trans-alkenoic acids of general formula CH3—(CH2)n—CH?(CH2)mCO2H where n=4 to 9 m=8 to 16. More particularly, the present invention relates to a process for the preparation of trans-tetracos-15-enoic acid, which is a bioactive constituent possessing dose-related hepatoprotective activity. The present invention also relates to the use thereof for hepatoprotection.
    Type: Grant
    Filed: March 28, 2002
    Date of Patent: February 8, 2005
    Assignee: Council of Scientific and Industrial Research
    Inventors: Vishwa Nath Gupta, Vikram Bhardwaj, Bhupinder Singh, Bal Krishan Chandan, Krishan Avtar Suri, Naresh Kumar Satti, Om Parkash Suri, Sukhdev Swami Handa
  • Synergistic hepatoprotective composition and a method thereof
    Publication number: 20040191309
    Abstract: The present invention relates to a synergistic formulation comprising trans-tetracos-15-enoic acid (t-TCA) and andrographolide (AP) in the ratio ranging between 1:7 to 7:1 (w/w), useful in hepatoprotection; and a process for the preparation of a synergistic formulation comprising trans-tetracos-15-enoic acid (t-TCA) and andrographolide (AP) useful in hepatoprotection, said process comprising steps of grounding the particles of the t-TCA and AP into fine particles, mixing the fine particles in ratio ranging between 1:7 to 7:1 (w/w), and grinding the mixture to obtain formulation, and also, a method of hepatoprotection of a subject using the synergistic formulation comprising trans-tetracos-15-enoic acid (t-TCA) and andrographolide (AP), said method comprising the steps of administering the formulation to the subject.
    Type: Application
    Filed: March 31, 2003
    Publication date: September 30, 2004
    Applicant: COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH
    Inventors: Vishwa Nath Gupta, Krishan Avtar Suri, Bishan Datt Gupta, Bupinder Singh Jaggi, Naresh Kumar Satti, Bal Krishan Chandan, Neelam Sharma, Vikram Bhardwaj, Om Parkash Suri, Ghulam Nabi Qazi, Jyotsna Suri, Madalsa Bargotra
  • Process for the synthesis of trans-alkenoic acids, use thereof
    Publication number: 20040024232
    Abstract: The present invention relates to a process for the preparation of trans-alkenoic acids of general formula CH3—(CH2)n—CH—(CH2)m CO2H where n=4 to 9 m−8 to 16. More particularly, the present invention relates to a process for he preparation of trans-tetracos-15-enoic acid, which is a bioactive constituent possessing dose-related hepatoprotective activity. The present invention also relates to the use thereof for hepatoprotection.
    Type: Application
    Filed: March 28, 2002
    Publication date: February 5, 2004
    Inventors: Vishwa Nath Gupta, Vikram Bhardwaj, Bhupinder Singh, Bal Krishan Chandan, Krishan Avtar Suri, Naresh Kumar Satti, Om Parkash Suri, Sukhdev Swami Handa
  • Process for the isolation of novel oligospirostanoside
    Patent number: 6670459
    Abstract: The present invention relates to a process for the isolation of a novel oligospirostanoside structurally constructed as 3-0-[&agr;-L-rhamnopyranosyl-(1→2)-&agr;-L-rhamnopyranosyl-(1→4)-0-&bgr;-D-glucopyranosyl]-25(S)-5&bgr; spirostan-3&bgr;-ol isolated from Asparagus racemosus and biologically evaluated as a potent immunomodulatory agent.
    Type: Grant
    Filed: March 20, 2002
    Date of Patent: December 30, 2003
    Assignee: Zandu Pharmaceutical Works Ltd.
    Inventors: Sukhdev Swami Handa, Om Prakash Suri, Vishwa Nath Gupta, Krishan Avtar Suri, Naresh Kumar Satti, Vikram Bhardwaj, Kasturi Lal Bedi, Anamika Khajuria, Anpurna Kaul, Girish G. Parikh, Prabhakar Kulhar, Ulhas Salunkhe, Raman Krishnamurthy
  • Oligospirostanoside, pharmaceutical composition containing novel oligospirostanoside and method for immunomodulation using said oligospirostanoside
    Patent number: 6649745
    Abstract: The present invention relates to a novel oligospirostanoside having the structure 3-0-[&agr;-L-rhamnopyranosyl-(1→2)-&agr;-L-rhamnopyranosyl-(1→4)-0-&bgr;-D-glucopyranosyl]-25(S)-5&bgr;-spirostan-3&bgr;-ol isolated from Asparagus racemosus and to a pharmaceutical composition containing the novel oligospirostanoside and to a method for immunomodulation using said oligospirostanoside by administering a pharmaceutically effective amount of said novel oligospirostanoside.
    Type: Grant
    Filed: March 20, 2002
    Date of Patent: November 18, 2003
    Assignees: Council of Scientific and Industrial Research, Department of Science and Technology, Zandu Pharmaceutical Works Limited
    Inventors: Sukhdev Swami Handa, Om Prakash Suri, Vishwa Nath Gupta, Krishan Avtar Suri, Naresh Kumar Satti, Vikram Bhardwaj, Kasturi Lal Bedi, Anamika Khajuria, Anpurna Kaul, Girish G. Parikh, Prabhakar Kulhar, Ulhas Salunkhe, Raman Krishnamurthy
  • NOVEL OLIGOSPIROSTANOSIDE, PHARMACEUTICAL COMPOSITION CONTAINING NOVEL OLIGOSPIROSTANOSIDE AND METHOD FOR IMMUNOMODULATION USING SAID OLIGOSPIROSTANOSIDE
    Publication number: 20030181396
    Abstract: The present invention relates to a novel oligospirostanoside having the structure 3-0-[&agr;-L-rhamnopyranosyl-(1→2)-&agr;-L-rhamnopyranosyl-(1→4)-0-&bgr;-D-glucopyranosyl]-25(S)-spirostan-3&bgr;-ol isolated from Asparagus racemosus and to a pharmaceutical composition containing the novel oligospirostanoside and to a method for immunomodulation using said oligospirostanoside by administering a pharmaceutically effective amount of said novel oligospirostanoside.
    Type: Application
    Filed: March 20, 2002
    Publication date: September 25, 2003
    Inventors: Sukhdev Swami Handa, Om Prakash Suri, Vishwa Nath Gupta, Krishan Avtar Suri, Naresh Kumar Satti, Vikram Bhardwaj, Kasturi Lal Bedi, Anamika Khajuria, Anpurna Kaul, Girish G. Parikh, Prabhakar Kulhar, Ulhas Salunkhe, Raman Krishnamurthy
  • Process for the isolation of novel oligospirostanoside
    Publication number: 20030181395
    Abstract: The present invention relates to a process for the isolation of a novel oligospirostanoside structurally constructed as 3-0-[&agr;-L-rhamnopyranosyl-(1→2)-&agr;-L-rhamnopyranosyl-(1→4)-0-&bgr;-D-glucopyranosyl]-25(S)-spirostan-3&bgr;-ol isolated from Asparagus racemosus and biologically evaluated as a potent immunomodulatory agent.
    Type: Application
    Filed: March 20, 2002
    Publication date: September 25, 2003
    Inventors: Sukhdev Swami Handa, Om Prakash Suri, Vishwa Nath Gupta, Krishan Avtar Suri, Naresh Kumar Satti, Vikram Bhardwaj, Kasturi Lal Bedi, Anamika Khajuria, Anpurna Kaul, Girish G. Parikh, Prabhakar Kulhar, Ulhas Salunkhe, Raman Krishnamurthy
  • Pharmaceutical composition and process for isolation of trans-tetracos-15-enoic acid and method of treatment for hepatotoxicity
    Publication number: 20030175363
    Abstract: The present invention relates to a pharmaceutical composition comprising a bioactive constituent trans-tetracos-15-enoic acid and a process for the isolation of tetracos-15-enoic acid from the plant Indigofera tinctoria along with a method of treatment for hepatotoxicity.
    Type: Application
    Filed: February 11, 2002
    Publication date: September 18, 2003
    Inventors: Sukhdev Swami Handa, Bupinder Singh, Bal Krishan Chandan, Ajit Kumar Saxena, Vikram Bhardwaj, V.N. Gupta, Om Parkash Suri, Naresh Kumar Satti, Krishan Avtar Suri
  • Synergistic composition of trans-tetracos-15-enoic acid and Apocynin and method of treatment for hepatotoxicity
    Publication number: 20030157198
    Abstract: The present invention relates to a synergistic hepatoprotective pharmaceutical composition comprising an effective amount of trans-tetracos-15-enoic acid (TCA) and Apocynin (APO), the present invention also relates to a method of treatment for hepatotoxicity in mammals and humans.
    Type: Application
    Filed: March 20, 2002
    Publication date: August 21, 2003
    Inventors: Sukhdev Swami Handa, Om Parkash Suri, V.N. Gupta, Krishan Avtar Suri, Naresh Kumar Satti, Vikram Bhardwaj, Bupinder Singh, Bal Krishan Chandan