Patents by Inventor Viktor Gyollai

Viktor Gyollai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Non-hygroscopic and powdery amorphous pimecrolimus
    Patent number: 7589100
    Abstract: An amorphous pimecrolimus and processes for providing an amorphous pimecrolimus are provided.
    Type: Grant
    Filed: December 1, 2005
    Date of Patent: September 15, 2009
    Assignee: TEVA Gyógyszergyár Zártkörún Müködö Részvénytársaság
    Inventors: Adrienne Kovacsne-Mezei, Csilla Nemethne Racz, Judith Aronhime, Csaba Szabo, Viktor Gyollai, Sandor Molnar, Micahel Pinchasov
  • Ascomycin and pimecrolimus having reduced levels of desmethylascomycin and 32-deoxy-32-epichloro-desmethylascomycin respectively, and methods for preparation thereof
    Publication number: 20090082386
    Abstract: Provided is ascomycin that has a low level of an FK523 impurity, and pimecrolimus that has a low level of a 32-deoxy-32-epichloro-FK523 impurity, methods of preparing them, and the use of such pimecrolimus for preparing a pharmaceutical composition.
    Type: Application
    Filed: November 6, 2007
    Publication date: March 26, 2009
    Inventors: Erzsebet Meszarosne Sos, Vilmos Keri, Andrea Csorvasi, Viktor Gyollai, Piroska Kovacs, Angela Simon, Jozsef Simulak
  • Aztreonam ? polymorph with very low residual solvent content
    Patent number: 7452991
    Abstract: The invention relates to the ? polymorph of Aztreonam, which contains less than 2.5% by weight residual solvent and to a process of making said polymorph. In the process of the invention, a polymorph of Aztreonam is dissolved in an absolute C1-6 alcohol in the presence of a base to form a solution, an acid is added to the solution, and the solution is stirred efficiently.
    Type: Grant
    Filed: May 17, 2004
    Date of Patent: November 18, 2008
    Assignee: Teva Gyógyszergyár Zártkörüen Müködö Részvénytársaság
    Inventors: Viktor Gyollai, Csaba Szabo, Claude Singer, Ehud Amir
  • Aztreonam L-lysine and methods for the preparation and analysis thereof
    Patent number: 7358093
    Abstract: The present invention relates to the L-lysine salt of aztreonam and methods for making the L-lysine salt of aztreonam.
    Type: Grant
    Filed: March 22, 2007
    Date of Patent: April 15, 2008
    Assignee: Corus Pharma, Inc.
    Inventors: Viktor Gyollai, Csaba Szabo, Claude Singer, Istvan Bodi
  • Methods of preparing pimecrolimus
    Publication number: 20070270451
    Abstract: The present invention provides a process for the preparation of pimecrolimus from ascomycin in which ascomycin is reacted with a conversion reagent that converts ascomycin to its activated derivative at C-32. The activated ascomycin is then reacted with chloride ion. The process of the invention requires fewer process steps than prior art processes, and does not require the protection of the ascomycin C-24 hydroxyl group or the purification of the activated ascomycin derivative.
    Type: Application
    Filed: July 24, 2007
    Publication date: November 22, 2007
    Inventors: Viktor Gyollai, Csaba Szabo
  • Methods of preparing pimecrolimus
    Patent number: 7279571
    Abstract: The present invention provides a process for the preparation of pimecrolimus from ascomycin in which ascomycin is reacted with a conversion reagent that converts ascomycin to its activated derivative at C-32. The activated ascomycin is then reacted with chloride ion. The process of the invention requires fewer process steps than prior art processes, and does not require the protection of the ascomycin C-24 hydroxyl group or the purification of the activated ascomycin derivative.
    Type: Grant
    Filed: December 1, 2005
    Date of Patent: October 9, 2007
    Assignee: TEVA Gyógyszergyár Zártkörüen Müködö Részvénytársaság
    Inventors: Viktor Gyollai, Csaba Szabo
  • Aztreonam L-lysine and methods for the preparation thereof
    Patent number: 7262293
    Abstract: The present invention relates to the L-lysine salt of aztreonam and methods for making the L-lysine salt of aztreonam.
    Type: Grant
    Filed: July 1, 2004
    Date of Patent: August 28, 2007
    Assignee: Corus Pharma
    Inventors: Viktor Gyollai, Csaba Szabo, Claude Singer, Istvan Bodi
  • Aztreonam L-lysine and methods for the preparation thereof
    Publication number: 20070167424
    Abstract: The present invention relates to the L-lysine salt of aztreonam and methods for making the L-lysine salt of aztreonam.
    Type: Application
    Filed: March 22, 2007
    Publication date: July 19, 2007
    Inventors: Viktor Gyollai, Csaba Szabo, Claude Singer, Istvan Bodi
  • Preparation of Aztreonam
    Patent number: 7145017
    Abstract: The invention relates to a process for the synthesis of Aztreonam. Specifically, the process entails hydrolyzing [3S-[3?(Z),4?]]-3-[[(2-amino-4-thiazolyl)[(1-t-butoxycarbonyl-1-methylethoxy)imino]acetyl]amino]-4-methyl-2-oxo-1-azetidinesulfonic acid (t-Bu Aztreonam) to form Aztreonam.
    Type: Grant
    Filed: August 5, 2003
    Date of Patent: December 5, 2006
    Assignee: TEVA Gyógyszergyár Zártkörűen Működő Részvénytársaság
    Inventors: Viktor Gyollai, Erzsebet Meszaros Sos, Csaba Szabo, Claude Singer, Szabolcs Salyi
  • Non-hygroscopic and powdery amorphous pimecrolimus
    Publication number: 20060147540
    Abstract: An amorphous pimecrolimus and processes for providing an amorphous pimecrolimus are provided.
    Type: Application
    Filed: December 1, 2005
    Publication date: July 6, 2006
    Inventors: Adrienne Kovacsne-Mezei, Csilla Racz, Judith Aronhime, Csaba Szabo, Viktor Gyollai, Sandor Molnar, Micahel Pinchasov
  • Methods of preparing pimecrolimus
    Publication number: 20060142564
    Abstract: The present invention provides a process for the preparation of pimecrolimus from ascomycin in which ascomycin is reacted with a conversion reagent that converts ascomycin to its activated derivative at C-32. The activated ascomycin is then reacted with chloride ion. The process of the invention requires fewer process steps than prior art processes, and does not require the protection of the ascomycin C-24 hydroxyl group or the purification of the activated ascomycin derivative.
    Type: Application
    Filed: December 1, 2005
    Publication date: June 29, 2006
    Inventors: Viktor Gyollai, Csaba Szabo
  • Aztreonam L-lysine and methods for the preparation thereof
    Publication number: 20050032775
    Abstract: The present invention relates to the L-lysine salt of aztreonam and methods for making the L-lysine salt of aztreonam.
    Type: Application
    Filed: July 1, 2004
    Publication date: February 10, 2005
    Inventors: Viktor Gyollai, Csaba Szabo, Claude Singer, Istvan Bodi
  • Aztreonam beta polymorph with very low residual solvent content
    Publication number: 20050014739
    Abstract: The invention relates to the ? polymorph of Aztreonam, which contains less than 2.5% by weight residual solvent and to a process of making said polymorph.
    Type: Application
    Filed: May 17, 2004
    Publication date: January 20, 2005
    Inventors: Viktor Gyollai, Csaba Szabo, Claude Singer
  • Processes for preparation of polymorphic forms of desloratadine
    Publication number: 20040242619
    Abstract: Provided are processes for preparation of polymorphic forms of desloratadine.
    Type: Application
    Filed: March 12, 2004
    Publication date: December 2, 2004
    Inventors: Zoltan G. Toth, Viktor Gyollai, Adrienne Kovacsne-Mezei, Csaba Szabo, Judith Aronhime, Claude Singer
  • Stable pharmaceutical compositions of desloratadine
    Publication number: 20040229896
    Abstract: Provided is a stable pharmaceutical composition of desloratadine.
    Type: Application
    Filed: March 12, 2004
    Publication date: November 18, 2004
    Inventors: Zoltan G. Toth, Viktor Gyollai, Adrienne Kovacsne-Mezei, Csaba Szabo, Judith Aronhime, Claude Singer
  • Preparation of aztreonam
    Publication number: 20040063682
    Abstract: The invention relates to a process for the synthesis of Aztreonam Specifically, the process entails hydrolyzing [3 S-[3&agr;(Z),4&bgr;]]-3-[[(2-amino-4-thiazolyl)[(1-t-butoxycarbonyl-1-methylethoxy)imino]acetyl]amino]-4-methyl-2-oxo-1-azetidinesulfonic acid (t-Bu Aztreonam) to form Aztreonam.
    Type: Application
    Filed: August 5, 2003
    Publication date: April 1, 2004
    Inventors: Viktor Gyollai, Erzsebet Meszaros Sos, Csaba Szabo, Claude Singer, Szabolcs Salyi