Patents by Inventor Viktor Magdolen

Viktor Magdolen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Urokinase inhibitors
    Patent number: 6680320
    Abstract: The invention relates to the use of derivatives of 3-amidinophenylalanine as urokinase inhibitors for treating malignant tumors and the formation of metastases.
    Type: Grant
    Filed: July 26, 2002
    Date of Patent: January 20, 2004
    Assignee: Wilex AG
    Inventors: Olaf Wilhelm, Viktor Magdolen, Jörg Stürzebecher, John Foekens, Verena Lutz
  • Urokinase inhibitors
    Patent number: 6624169
    Abstract: The invention relates to the use of derivatives of 3-amidinophenylalanine as urokinase inhibitors for treating malignant tumors and the formation of metastases.
    Type: Grant
    Filed: April 3, 2001
    Date of Patent: September 23, 2003
    Assignee: Wilex Biotechnology GmbH
    Inventors: Olaf Wilhelm, Viktor Magdolen, Jörg Stürzebecher, John Foekens, Verena Lutz
  • Highly selective inhibitors of the urokinase plasminogen activator
    Publication number: 20030100584
    Abstract: The invention relates to novel selective inhibitors of the urokinase plasminogen activator (uPA, EC 3.4.21.31), of the arylguanidine type.
    Type: Application
    Filed: September 20, 2002
    Publication date: May 29, 2003
    Inventors: Viktor Magdolen, Stefan Speri, Joerg Stuerzebecher, Olaf Wilhelm, Nuria Arroyo De Prada, Luis Moroder, Robert Huber, Uwe Jacob, Wolfram Bode
  • Inhibitors for urokinase receptor
    Patent number: 6528619
    Abstract: The present invention provides peptides as inhibitors of the binding of urokinase to the urokinase receptor. The peptides have the general structural formula (I): X1-[X2]n-X3-X4-K-Y-F-X5-X6-I-X7-W-[X8]m  (I) in which X1, X2, X3, X4, X5, X6, X7 and X8 each denote an aminocarboxylic acid, n and m are each independently 0 or 1, K denotes an aminocarboxylic acid with a lysine side chain, Y denotes an aminocarboxylic acid with a tyrosine side chain, F denotes an aminocarboxylic acid with a phenyl-alanine side chain, I denotes an aminocarboxylic acid with an isoleucine side chain, W denotes an aminocarboxylic acid with a tryptophan side chain, and the monomeric building blocks are linked by —CONR1— or —NR1CO— bonds where R1 in each case independently denotes hydrogen, methyl or ethyl, and pharmaceutically compatible salts and derivatives thereof.
    Type: Grant
    Filed: January 10, 2000
    Date of Patent: March 4, 2003
    Assignee: Roche Diagnostics GmbH
    Inventors: Markus Bürgle, Heinrich Graeff, Horst Kessler, Viktor Magdolen, Bernhard König, Marcus Koppitz, Christoph Riemer, Manfred Schmitt, Ulrich Weidle
  • Novel urokinase inhibitors
    Publication number: 20030013723
    Abstract: The invention relates to the use of derivatives of 3-amidinophenylalanine as urokinase inhibitors for treating malignant tumors and the formation of metastases.
    Type: Application
    Filed: July 26, 2002
    Publication date: January 16, 2003
    Applicant: Wilex AG
    Inventors: Olaf Wilhelm, Viktor Magdolen, Jorg Sturzebecher, John Foekens, Verena Lutz
  • Anaesthetical circuit with reverse inhalation equipped with an injector of escaped anaesthetics
    Patent number: 4691700
    Abstract: An improved anaesthetical circuit with reverse inhalation is equipped with an injector of escaped anaesthetics connected by an inlet pipe to a valve in which a feeding pipe, leading from a source of constant flow, discharges a signal from a differential pressure indicator, being led into the valve through a conduit. The differential pressure indicator is fed from an energy source, on one hand, together with a conduit pipe leading from a drive pipe into the pressurized chamber of the differential pressure indicator, and a pipe leading from a connection pipe into the vacuum chamber of the differential pressure indicator, on the other hand. A connection pipe connecting an outlet pipe of the injector through a check valve with a rubber bag, which is arranged in a cylinder attached to the anaesthetical circuit.
    Type: Grant
    Filed: June 2, 1986
    Date of Patent: September 8, 1987
    Assignee: Konstructa Trencin, narodny podnik
    Inventors: Ondrej Brychta, Jozef Tlucko, Viktor Magdolen, Miroslav Brostik, Dusan Klimacek