Abstract: The present disclosure is directed to a big-bag transfer station for API seed crystals. The transfer station may permit the filling of smaller containers, such as bags or pouches, from a large container, such as a big bag. The transfer station may permit the transfer without contaminating the atmosphere of the room in which the station is housed. Additionally, the transfer station may limit cross-contamination between filling cycles by employing single-use liners.

Abstract: A method and device for creating an environmentally sealed connection for transfer between a first region and a second region, the first region and the second region each having an at least partially flexible barrier with connection portions, comprising the following steps: (i) superposition of said connection portions of the barriers in a sandwich arrangement, wherein each connection portion comprises a first area at least partially made of thermo-resistant material and a second area comprising a first welding band zone of a closed geometrical shape, said first and second area of each barrier being arranged to face one another, with the first areas of the two barriers forming the outside layers of the sandwich arrangement, and the second areas of the two barriers forming the inside layers of the sandwich arrangement, wherein the first areas are positioned to cover the first welding band zones of the second zones, (ii) joining the second areas by welding of the first closed welding band zones, whereby a first

Abstract: The present disclosure is directed to a big-bag transfer station for API seed crystals. The transfer station may permit the filling of smaller containers, such as bags or pouches, from a large container, such as a big bag. The transfer station may permit the transfer without contaminating the atmosphere of the room in which the station is housed. Additionally, the transfer station may limit cross-contamination between filling cycles by employing single-use liners.

Abstract: A clip-closure (1, 2) for closing container systems made from film, includes first closure and second closure part (4,5). A connecting device secures the second closure part (5) to the first closure part (4) in the assembled state. The first closure part (4) may be of U-shaped configuration and includes two limbs (7, 8). The second closure part (5) is of W-shaped configuration and includes a central limb (6) as well as two side limbs (9, 10) spaced apart therefrom. A first part of the connecting device is provided on the limbs (7, 8) of the first closure part (4), and a second part of the connecting device is provided on the side limbs (9, 10) of the second closure part (5). The disclosure also relates to opening tools (41).

Abstract: A method of transferring at least one object, sterilised and packed into a bag, into a clean room, where the bag is connected with an inner liner connecting the clean room with an outer room and on this is opened at an area open towards the inner liner so that a tube-like connection, closed towards the outer room, is formed between the interior of the bag and the inner liner, through which the at least one object is transferred into the clean room.

Abstract: A device and a method for decanting powders and solid substances or materials while avoiding contamination and a novel use of a weldable and peelable continuous tubular film (1). The invention provides a basic version, with which it is simply possible to work free from contamination and a further-developed form, with which it is also possible, in addition to avoiding contamination, to perform decanting under sterile conditions.