Abstract: The invention relates to a sorption agent for removing endotoxins from a biological fluid, comprising a water-insoluble, porous carrier having a neutral hydrophobic surface wherein the surface of the carrier has an adsorptive coating made of polymyxin and albumin, wherein polymyxin and albumin are bonded to the surface of the carrier in a noncovalent manner. The invention further relates to a method for producing such a sorption agent. The sorption agent is used in extracorporeal blood purification, in particular in order to treat individuals, who have sepsis.

Abstract: The invention relates to a sorption agent having improved selectivity properties for removing protein-bound substances from a biological fluid, in particular blood or blood plasma of patients having severe disturbances of the liver function or liver failure and having kidney insufficiency, thee sorption agent having: (a) a porous, neutral, hydrophobic polymer and (b) a polypeptide layer adsorbed on the polymer, the neutral, hydrophobic polymer having a mean pore size of at least 15 nm. Furthermore, the invention relates to methods and uses in connection with such a sorption agent. The invention is used in particular in extracorporeal liver support.

Abstract: The invention relates to a sorption agent for removing endotoxins from a biological fluid, comprising a water-insoluble, porous carrier having a neutral hydrophobic surface wherein the surface of the carrier has an adsorptive coating made of polymyxin and albumin, wherein polymyxin and albumin are bonded to the surface of the carrier in a noncovalent manner. The invention further relates to a method for producing such a sorption agent. The sorption agent is used in extracorporeal blood purification, in particular in order to treat individuals, who have sepsis.

Abstract: The invention relates to a sorption agent for removing endotoxins from a biological fluid, the sorption agent having a water-insoluble, porous carrier and polymyxin, which is immobilized on the carrier, the carrier having a neutral, hydrophobic surface and polymyxin being immobilized on the surface of the carrier via hydrophobic interaction. The sorption agent is used in extracorporeal blood purification, in particular for treating individuals with sepsis.

Abstract: The invention relates to a sorption agent having improved selectivity properties for removing protein-bound substances from a biological fluid, in particular blood or blood plasma of patients having severe disturbances of the liver function or liver failure and having kidney insufficiency, the sorption agent having: (a) a porous, neutral, hydrophobic polymer and (b) a polypeptide layer adsorbed on the polymer, the neutral, hydrophobic polymer having a mean pore size of at least 15 nm. Furthermore, the invention relates to methods and uses in connection with such a sorption agent. The invention is used in particular in extracorporeal liver support.