Patents by Inventor Vilas Hareshwar Dahanukar

Vilas Hareshwar Dahanukar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Amine salt of obeticholic acid
    Patent number: 11168107
    Abstract: The present application relates to amine salt of obeticholic acid. Specifically, the present application relates to (S)-?-methylbenzylamine and diethylamine salt of obeticholic acid. The present application also relates to a process for preparation of amorphous form of obeticholic acid comprising converting amine salt of obeticholic acid to amorphous form of obeticholic acid.
    Type: Grant
    Filed: February 10, 2017
    Date of Patent: November 9, 2021
    Assignee: DR. REDDY'S LABORATORIES LIMITED
    Inventors: Satishbhai Sukhlalbhai More, Vikas Sadashiv Gajare, Sandip Ramdas Khobare, Krishna Mohan Thalabathula, Vilas Hareshwar Dahanukar, Shirshendu Das Gupta
  • Process for preparation of eribulin and intermediates thereof
    Patent number: 11059799
    Abstract: The present application relate to a process for preparation of 4-Methylene tetrahydrofuran compound of formula II, which is useful as an intermediate for the preparation of halichondrin B analogues such as Eribulin.
    Type: Grant
    Filed: May 25, 2017
    Date of Patent: July 13, 2021
    Assignee: DR. REDDY'S LABORATORIES LIMITED.
    Inventors: Sudhir Sai, Debjit Basu, Kumar Sarvesh, Uday Kumar Neelam, Amit Kumar Mandal, Rakeshwar Bandichhor, Vilas Hareshwar Dahanukar
  • AMINE SALT OF OBETICHOLIC ACID
    Publication number: 20210188896
    Abstract: The present application relates to amine salt of obeticholic acid. Specifically, the present application relates to (S)-?-methylbenzylamine and diethylamine salt of obeticholic acid. The present application also relates to a process for preparation of amorphous form of obeticholic acid comprising converting amine salt of obeticholic acid to amorphous form of obeticholic acid.
    Type: Application
    Filed: February 10, 2017
    Publication date: June 24, 2021
    Inventors: Satishbhai Sukhlalbhai More, Vikas Sadashiv Gajare, Sandip Ramdas Khobare, Krishna Mohan Thalabathula, Vilas Hareshwar Dahanukar, Shirshendu Das Gupta
  • ALTERNATE PROCESSES FOR THE PREPARATION OF PYRROLIDINE DERIVATIVES
    Publication number: 20210163409
    Abstract: Aspects of the present application relate to process for the preparation of Pyrrolidine derivatives useful as key intermediates for active ingredients. Specific aspects relate to alternate process for the preparation of Upadacitinib intermediate, 4-ethylpyrrolidine-3-carboxylic acid, its ester or a salt thereof. Processes disclosed here in are cost effective and industrially viable as compared to known processes.
    Type: Application
    Filed: July 19, 2018
    Publication date: June 3, 2021
    Inventors: Srinivas ORUGANTI, Bhaskar KANDAGATLA, Saikat SEN, Raju CHEERLAVANCHA, Magesh SAMPATH, Martin FOX, Vilas Hareshwar DAHANUKAR
  • Process for preparation of obeticholic acid
    Patent number: 10875887
    Abstract: The invention of the present application relates to the process for the preparation of intermediates of obeticholic acid and their conversion to obeticholic acid. The process involves the conversion of compound of formula (VI) to compound of formula (VII) in presence of an organic base.
    Type: Grant
    Filed: May 31, 2017
    Date of Patent: December 29, 2020
    Assignee: DR. REDDY'S LABORATORIES LIMITED.
    Inventors: Vilas Hareshwar Dahanukar, Rama Mohan Hindupur, Rashid Abdul Rehman Khan, Satishbhai Sukhlalbhai More, Vikas Sadashiv Gajare, Sandip Ramdas Khobare, Krishna Mohan Thalabathula, Rajender Datrika, Sreenivasulu Madi Shetty
  • PROCESSES FOR PREPARATION OF LIFITEGRAST AND INTERMEDIATES THEREOF
    Publication number: 20200369652
    Abstract: The present invention provides process for preparation of lifitegrast, amine salts of lifitegrast, process for preparation of amine salts of lifitegrast and their use in purification of lifitegrast, and also provided are process for preparation of amorphous lifitegrast and pharmaceutical compositions comprising lifitegrast prepared by the processes of the present invention.
    Type: Application
    Filed: August 2, 2018
    Publication date: November 26, 2020
    Inventors: Srinivas ACHANTA, Ramesh CHAKKA, Vilas Hareshwar DAHANUKAR, Elati Ravi Rama CHANDRASEKHAR, Srinivasa Reddy BHIMAVARAPU, Mahendar MADARABOINA
  • PROCESS FOR PREPARATION OF OBETICHOLIC ACID
    Publication number: 20200317715
    Abstract: The invention of the present application relates to the process for the preparation of intermediates of obeticholic acid and their conversion to obeticholic acid. The process involves the conversion of compound of formula (VI) to compound of formula (VII) in presence of an organic base.
    Type: Application
    Filed: May 31, 2017
    Publication date: October 8, 2020
    Inventors: Vilas Hareshwar Dahanukar, Rama Mohan Hindupur, Rashid Abdul Rehman Khan, Satishbhai Sukhlalbhai More, Vikas Sadashiv Gajare, Sandip Ramdas Khobare, Krishna Mohan Thalabathula, Rajender Datrika, Sreenivasulu Madi Shetty
  • PROCESS FOR PREPARATION OF ERIBULIN AND INTERMEDIATES THEREOF
    Publication number: 20190276470
    Abstract: The present application relate to process for preparation of tetrahydrofuran compound of formula II, 4-Methylene tetrahydrofuran compound of formula V and tetrahydropyran compound of formula IX which are useful as intermediates for the preparation of halichondrin B analogues such as Eribulin or its pharmaceutically acceptable salts.
    Type: Application
    Filed: November 23, 2017
    Publication date: September 12, 2019
    Inventors: Michael Charles LLOYD, Pallavi RAO, Vishnu Vardhana Vema Reddy EDA, Srinivas ORUGANTI, Kumar SARVESH, Debjit BASU, Raja gopal PENUMANDLA, Prapulla Kumar PALVAI, Amit Kumar MANDAL, Vilas Hareshwar DAHANUKAR, Graham Andrew MEEK, Sarah Ann WARREN, Martin Edward FOX, Robert Wen Ming DAVIDSON
  • SOLID FORMS OF VENETOCLAX AND PROCESSES FOR THE PREPARATION OF VENETOCLAX
    Publication number: 20190185471
    Abstract: Aspects of the present application relate to solid forms of Venetoclax and preparative processes thereof. Specific aspects relate to an amorphous form of Venetoclax, its solid dispersion and crystalline forms of Venetoclax or salts thereof. Further aspects of the present application relate to processes for the preparation of Venetoclax.
    Type: Application
    Filed: June 8, 2017
    Publication date: June 20, 2019
    Applicant: Dr. Reddy's Laboratories Limited
    Inventors: Subba Reddy PEDDI REDDY, Mohan Kumar KOTTUR, Ramprasad JURUPULA, Mohammed Azeezulla BAIG, Ramesh CHAKKA, Rajesh THI PPARABOINA, Vishweshwar PEDDY, Pallavi RAO, Srinivas ORUGANTI, Vilas Hareshwar DAHANUKAR
  • PROCESS FOR PREPARATION OF ERIBULIN AND INTERMEDIATES THEREOF
    Publication number: 20190177291
    Abstract: The present application relate to a process for preparation of 4-Methylene tetrahydrofuran compound of formula II, which is useful as an intermediate for the preparation of halichondrin B analogues such as Eribulin.
    Type: Application
    Filed: May 25, 2017
    Publication date: June 13, 2019
    Inventors: Sudhir Sai, Debjit Basu, Kumar Sarvesh, Uday Kumar Neelam, Amit Kumar Mandal, Rakeshwar Bandichhor, Vilas Hareshwar Dahanukar
  • PROCESS FOR THE PREPARATION OF SUVOREXANT AND INTERMEDIATES USEFUL IN THE SYNTHESIS OF SUVOREXANT
    Publication number: 20160168138
    Abstract: A novel processes for the preparation of suvorexant (formula I), its related compounds and its intermediates that are simple, economical and commercially viable.
    Type: Application
    Filed: July 15, 2014
    Publication date: June 16, 2016
    Inventors: Javed IQBAL, Vilas Hareshwar DAHANUKAR, Srinivas ORUGANTI, Bhaskar KANDAGATLA
  • Preparation of ticagrelor
    Patent number: 9233966
    Abstract: Provided are processes for preparing Ticagrelor and its intermediates that are useful in the processes. Also provided are salts of Ticagrelor, their processes and solid dispersion of Ticagrelor having Ticagrelor in amorphous form.
    Type: Grant
    Filed: April 5, 2013
    Date of Patent: January 12, 2016
    Assignee: DR. REDDY'S LABORATORIES LIMITED
    Inventors: Vilas Hareshwar Dahanukar, Goverdhan Gilla, Sreenivasulu Kurella, Shweta Mahajan Kulkarni, Raghupathi Reddy Anumula, Sampath Aalla, Yakambram Bojja, Ravi Ram Chandra Sekhar Elati, Veerender Murki, Venkata Annapurna Sasikala Cheemalapati
  • Process for producing (S)-equol
    Patent number: 9051291
    Abstract: The present application relates to an improved process for the preparation of (S)-equol (1). The present application also relates to novel intermediates of formula (7), (7A), (8) and (9) and their use for the synthesis of (S)-equol.
    Type: Grant
    Filed: March 27, 2013
    Date of Patent: June 9, 2015
    Assignee: DR. REDDY'S LABORATORIES LIMITED
    Inventors: Vilas Hareshwar Dahanukar, Syam Kumar Unniaran Kunhimon, Upadhya Timmana, Abir Kumar Pal, Mahendar Macha, Venkata Madhubabu Meesala, Krishna Mohan Thalabathula, Shankar Ramanathan
  • PREPARATION OF TICAGRELOR
    Publication number: 20150073146
    Abstract: Provided are processes for preparing Ticagrelor and its intermediates that are useful in the processes. Also provided are salts of Ticagrelor, their processes and solid dispersion of Ticagrelor having Ticagrelor in amorphous form.
    Type: Application
    Filed: April 5, 2013
    Publication date: March 12, 2015
    Inventors: Vilas Hareshwar Dahanukar, Goverdhan Gilla, Sreenivasulu Kurella, Shweta Mahajan Kulkarni, Raghupathi Reddy Anumula, Sampath Aalla, Yakambram Bojja, Ravi Ram Chandra Sekhar Elati, Veerender Murki, Venkata Annapurna Sasikala Cheemalapati
  • PROCESS FOR PRODUCING (S)-EQUOL
    Publication number: 20150057456
    Abstract: The present application relates to an improved process for the preparation of (S)-equol (1). The present application also relates to novel intermediates of formula (7), (7A), (8) and (9) and their use for the synthesis of (5)-equol.
    Type: Application
    Filed: March 27, 2013
    Publication date: February 26, 2015
    Inventors: Vilas Hareshwar Dahanukar, Syam Kumar Unniaran Kunhimon, Upadhya Timmana, Abir Kumar Pal, Mahendar Macha, Venkata Madhubabu Meesala, Krishna Mohan Thalabathula, Shankar Ramanathan
  • PROCESS FOR PREPARATION OF PREGABALIN
    Publication number: 20140243412
    Abstract: Aspects of the present invention relate to improved process for preparation of (R)(?)-3-(carbamoylmethyl)-5-methylhexanoic acid (R-CMHA) of the formula (II) or its pharmaceutically acceptable salts in the presence of a lewis acid, process for preparation of pregabalin using R-CMHA of the formula (II) or its pharmaceutically acceptable salts prepared according to the present invention and process for preparation of pregabalin with low amount of undesired impurity.
    Type: Application
    Filed: February 27, 2014
    Publication date: August 28, 2014
    Applicant: Dr. Reddy's Laboratories Ltd.
    Inventors: Srinivas GANGULA, Uday Kumar NEELAM, Krishna VINIGARI, Vilas Hareshwar DAHANUKAR, Syam Kumar Unniaran KUNHIMON, Srinivas Reddy GADE
  • LORCASERIN HYDROCHLORIDE
    Publication number: 20140187538
    Abstract: The present invention relates to amorphous lorcaserin hydrochloride; amorphous solid dispersion comprising lorcaserin hydrochloride and one or more pharmaceutically acceptable carries; processes for preparation thereof; pharmaceutical compositions comprising amorphous lorcaserin hydrochloride and one or more pharmaceutically acceptable carries.
    Type: Application
    Filed: December 26, 2013
    Publication date: July 3, 2014
    Applicant: DR. REDDY'S LABORATORIES LTD.
    Inventors: Rajesham Boge, Arjun Kumar Tummala, Vishweshwar Peddy, Srinivasulu Rangineni, Vilas Hareshwar Dahanukar, Bandichhor Rakeshwar, Areveli Srinivas, Macharla Prabhakar, Varanasi Ganesh
  • PREPARATION OF LUBIPROSTONE
    Publication number: 20130184476
    Abstract: Aspects of the present application relate to process for the preparation of lubiprostone.
    Type: Application
    Filed: July 11, 2012
    Publication date: July 18, 2013
    Inventors: Mark Jackson, Vilas Hareshwar Dahanukar, Suju Chuttippari Joseph, Vishnu Vardhana Verma Reddy Eda, Sandip Khobare Ramdas
  • PROCESS FOR THE PREPARATION OF A SINGLE ENANTIOMER OF 3-AMINOPIPERIDINE DIHYDROCHLORIDE
    Publication number: 20130172562
    Abstract: A process comprising: (a) reduction of N-acetyl-3-aminopyridine (2): or its salt in the presence of hydrogen and a palladium catalyst deposited on solid support; (b) converting racemic N-acetyl-3-aminopiperidine (3) or its salt produced in step (a) to rac-3-aminopiperidine (rac-4) or its salt; (c) resolution of the racemic 3-aminopiperidine (rac-4) or its salt produced in step (b) with a chiral acid.
    Type: Application
    Filed: June 17, 2011
    Publication date: July 4, 2013
    Applicants: DR. REDDY'S LABORATORIES, INC., DR. REDDY'S LABORATORIES LTD.
    Inventors: Graham Andrew Meek, Syam Kumar Unniaran Purakkal Kunhimon, R Shankar, Vilas Hareshwar Dahanukar, TH. Krishna Mohan, Manoj Balu Wagh, Abir Kumar Pal, V. Madhu Babu Meesala, Sonmit Shrivastava