Patents by Inventor Villendra Singh Negi

Villendra Singh Negi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • One pot synthesis of [2,8-Bis (trifluoromethyl)-4-quinolinyl]-2-pyridinylmethanone, a mefloquine intermediate
    Patent number: 6500955
    Abstract: The present invention provides a simple single step process for the preparation of [2,8-bis(trifluoromethyl)-4-quinolinyl]-2-pyridinylmethanone, comprising the step of condensing a halo-quinoline with an alpha-picolyl derivatives in the presence of a solvent, a base and a phase transfer catalyst at −10° C. to +90° C.
    Type: Grant
    Filed: January 30, 2002
    Date of Patent: December 31, 2002
    Assignee: National Institute of Pharmaceutical Education and Research
    Inventors: Harmander Pal Singh Chawla, Perminder Singh Johar, Alka Mittal, Ram Avtar Meena, Villendra Singh Negi
  • ONE POT SYNTHESIS OF [2, 8-BIS (TRIFLUOROMETHYL)-4- QUINOLINYL]2-PYRIDINYLMETHANONE, A MEFLOQUINE INTERMEDIATE
    Publication number: 20020188129
    Abstract: The present invention provides a simple single step process for the preparation of [2,8-bis (trifluoromethyl)-4-quinolinyl]-2 -pyridinylmethanone, comprising the step of condensing a halo-quinoline with an alpha-picolyl derivatives in the presence of a solvent, a base and a phase transfer catalyst at −10° C. to +90° C.
    Type: Application
    Filed: January 30, 2002
    Publication date: December 12, 2002
    Applicant: NATIONAL INSTITUTE OF PHARMACEUTICAL EDUCATION AND RESEARCH
    Inventors: Harmander Pal Singh Chawla, Perminder Singh Johar, Alka Mittal, Ram Avtar Meena, Villendra Singh Negi