Patents by Inventor Vimal Varghese

Vimal Varghese has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SOLID FORMS OF A THIENOPYRIMIDINEDIONE ACC INHIBITOR AND METHODS FOR PRODUCTION THEREOF
    Publication number: 20220064181
    Abstract: The present invention provides solid forms of compounds useful as inhibitors of Acetyl CoA Carboxylase (ACC), compositions thereof, methods of producing the same, and methods of using the same in the treatment of ACC-mediated diseases.
    Type: Application
    Filed: August 3, 2021
    Publication date: March 3, 2022
    Inventors: Katy Alexander, John C. Amedio, JR., Selcuk Calimsiz, Michael Geier, Geraldine C. Harriman, Sijun Hu, Jon P. Lawson, Henry Morrison, Kyle Sabourin, Mark E. Scott, Vimal Varghese, Kunal Arvind Varia, Xiaotian Wang, Xiaowei Yang
  • PROCESSES FOR PREPARING ACC INHIBITORS AND SOLID FORMS THEREOF
    Publication number: 20210024537
    Abstract: The present disclosure provides solid forms, including a salt or co-crystal, of Compound I: which exhibits Acetyl-CoA carboxylase (“ACC”) inhibitory activity and may be useful in treating ACC mediated diseases. Also provided herein are processes or steps for the preparation of a Compound I and intermediates useful for the processes or steps described herein.
    Type: Application
    Filed: July 9, 2020
    Publication date: January 28, 2021
    Inventors: Michael Geier, Luke Humphreys, Norihiro Ikemoto, Sean Liew, Henry Morrison, Mark E. Scott, Vimal Varghese
  • PROCESSES FOR PREPARING ACC INHIBITORS AND SOLID FORMS THEREOF
    Publication number: 20200199147
    Abstract: The present disclosure provides solid forms, including a salt or co-crystal, of Compound I: which exhibits Acetyl-CoA carboxylase (“ACC”) inhibitory activity and may be useful in treating ACC mediated diseases. Also provided herein are processes or steps for the preparation of a Compound I and intermediates useful for the processes or steps described herein.
    Type: Application
    Filed: November 20, 2019
    Publication date: June 25, 2020
    Inventors: Michael Geier, Luke Humphreys, Norihiro Ikemoto, Sean Liew, Henry Morrison, Mark E. Scott, Vimal Varghese
  • SOLID FORMS OF A THIENOPYRIMIDINEDIONE ACC INHIBITOR AND METHODS FOR PRODUCTION THEREOF
    Publication number: 20200148699
    Abstract: The present invention provides solid forms of compounds useful as inhibitors of Acetyl CoA Carboxylase (ACC), compositions thereof, methods of producing the same, and methods of using the same in the treatment of ACC-mediated diseases.
    Type: Application
    Filed: October 10, 2019
    Publication date: May 14, 2020
    Inventors: Katy Alexander, John C. Amedio, JR., Selcuk Calimsiz, Michael Geier, Geraldine C. Harriman, Sijun Hu, Jon P. Lawson, Henry Morrison, Kyle Sabourin, Mark E. Scott, Vimal Varghese, Kunal Arvind Varia, Xiaotian Wang, Xiaowei Yang
  • Processes for preparing ACC inhibitors and solid forms thereof
    Patent number: 10519165
    Abstract: The present disclosure provides solid forms, including a salt or co-crystal, of Compound I: which exhibits Acetyl-CoA carboxylase (“ACC”) inhibitory activity and may be useful in treating ACC mediated diseases. Also provided herein are processes or steps for the preparation of a Compound I and intermediates useful for the processes or steps described herein.
    Type: Grant
    Filed: March 2, 2018
    Date of Patent: December 31, 2019
    Assignee: Gilead Sciences, Inc.
    Inventors: Michael Geier, Norihiro Ikemoto, Sean Liew, Mark E. Scott, Vimal Varghese
  • Solid forms of a thienopyrimidinedione ACC inhibitor and methods for production thereof
    Patent number: 10487090
    Abstract: The present invention provides solid forms of compounds useful as inhibitors of Acetyl CoA Carboxylase (ACC), compositions thereof, methods of producing the same, and methods of using the same in the treatment of ACC-mediated diseases.
    Type: Grant
    Filed: December 12, 2018
    Date of Patent: November 26, 2019
    Assignee: Gilead Apollo, LLC
    Inventors: Selcuk Calimsiz, Michael Geier, Geraldine C. Harriman, Jon P. Lawson, Kyle Sabourin, Mark E. Scott, Vimal Varghese, Xiaotian Wang, Xiaowei Yang
  • SOLID FORMS OF A THIENOPYRIMIDINEDIONE ACC INHIBITOR AND METHODS FOR PRODUCTION THEREOF
    Publication number: 20190225623
    Abstract: The present invention provides solid forms of compounds useful as inhibitors of Acetyl CoA Carboxylase (ACC), compositions thereof, methods of producing the same, and methods of using the same in the treatment of ACC-mediated diseases.
    Type: Application
    Filed: December 12, 2018
    Publication date: July 25, 2019
    Inventors: Katy Alexander, John C. Amedio, JR., Selcuk Calimsiz, Michael Geier, Geraldine C. Harriman, Sijun Hu, Jon P. Lawson, Henry Morrison, Kyle Sabourin, Mark E. Scott, Vimal Varghese, Kunal Arvind Varia, Xiaotian Wang, Xiaowei Yang
  • PROCESSES FOR PREPARING ACC INHIBITORS AND SOLID FORMS THEREOF
    Publication number: 20180298025
    Abstract: The present disclosure provides solid forms, including a salt or co-crystal, of Compound I: which exhibits Acetyl-CoA carboxylase (“ACC”) inhibitory activity and may be useful in treating ACC mediated diseases. Also provided herein are processes or steps for the preparation of a Compound I and intermediates useful for the processes or steps described herein.
    Type: Application
    Filed: March 2, 2018
    Publication date: October 18, 2018
    Inventors: Michael Geier, Luke Humphreys, Norihiro Ikemoto, Sean Liew, Henry Morrison, Mark E. Scott, Vimal Varghese
  • SOLID FORMS OF A THIENOPYRIMIDINEDIONE ACC INHIBITOR AND METHODS FOR PRODUCTION THEREOF
    Publication number: 20170267690
    Abstract: The present invention provides solid forms of compounds useful as inhibitors of Acetyl CoA Carboxylase (ACC), compositions thereof, methods of producing the same, and methods of using the same in the treatment of ACC-mediated diseases.
    Type: Application
    Filed: March 1, 2017
    Publication date: September 21, 2017
    Inventors: Katy Alexander, John C. Amedio, JR., Selcuk Calimsiz, Michael Geier, Geraldine C. Harriman, Sijun Hu, Jon P. Lawson, Henry Morrison, Kyle Sabourin, Mark E. Scott, Vimal Varghese, Kunal Arvind Varia, Xiaotin Wang, Xiaowei Yang
  • Process for preparing morphine compounds
    Patent number: 9126965
    Abstract: The present application relates to processes for the preparation of morphine compounds utilizing a novel intramolecular [4+2] cycloaddition reaction.
    Type: Grant
    Filed: February 23, 2015
    Date of Patent: September 8, 2015
    Assignee: Brock University
    Inventors: Vimal Varghese, Tomas Hudlicky
  • PROCESS FOR PREPARING MORPHINE COMPOUNDS
    Publication number: 20150239860
    Abstract: The present application relates to processes for the preparation of morphine compounds utilizing a novel intramolecular [4+2] cycloaddition reaction.
    Type: Application
    Filed: February 23, 2015
    Publication date: August 27, 2015
    Applicant: Brock University
    Inventors: Vimal Varghese, Tomas Hudlicky