Patents by Inventor Vimala S. Sivaraman

Vimala S. Sivaraman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antisense oligonucleotides for mitogen-activated protein kinases as therapy for cancer
    Patent number: 6271210
    Abstract: A method is disclosed for inhibiting malignant neoplastic growth of epithelial or endothelial cells in a mammal by administering to the mammal an effective amount of an oligonucleotide complementary to at least a portion of mRNA for ERK-1 or ERK-2 that is overexpressed in the mammal. The antisense oligonucleotides are administered to the mammal as a dosage unit. A method of identifying and monitoring potentially malignant neoplastic cell growth in a mammal is also disclosed.
    Type: Grant
    Filed: October 5, 1999
    Date of Patent: August 7, 2001
    Assignee: The Research Foundation of SUNY
    Inventors: Vimala S. Sivaraman, Hsien-yu Wang, Craig C. Malbon
  • Antisense oligonucleotides for mitogen-activated protein kinases as therapy for cancer
    Patent number: 6007991
    Abstract: A method is disclosed for inhibiting malignant neoplastic growth of epithelial or endothelial cells in a mammal by administering to the mammal an effective amount of an oligonucleotide complementary to at least a portion of mRNA for ERK-1 or ERK-2 that is overexpressed in the mammal. The antisense oligonucleotides are administered to the mammal as a dosage unit. A method of identifying and monitoring potentially malignant neoplastic cell growth in a mammal is also disclosed.
    Type: Grant
    Filed: August 12, 1997
    Date of Patent: December 28, 1999
    Assignee: The Research Foundation of SUNY
    Inventors: Vimala S. Sivaraman, Hsien-yu Wang, Craig C. Malbon