Abstract: A method performed by a multi-subscriber identity module (MUSIM) user equipment (UE) for continuing operation of the MUSIM UE in a first mode, the MUSIM UE including a first SIM and a second SIM, and the method including transmitting, by the MUSIM UE, an uplink signalling message in response to determining a trigger condition has been satisfied, the uplink signalling message including one of compatible band information for the first SIM and the SIM, or one or more other stacks serving band information associated with the second SIM, receiving, by the MUSIM UE from a network, a radio resource control (RRC) reconfiguration signalling message for performing at least one activity at the first SIM in response to the transmitting the uplink signalling message, and performing, by the MUSIM UE, the at least one activity based on the RRC reconfiguration signalling message.

Abstract: The present invention provides for improved therapeutic regimens for treating benign hyperproliferative diseases and cancers. The Egr-1 promoter, long known to be radiation-responsive, has now been shown to be inducible for DNA damaging chemical agents, many of which themselves are used in therapies. Thus, the present invention provides for the advantageous combination of a DNA damaging chemical and an expression vector containing a therapeutic gene driven by the Egr-1 promoter.