Abstract: The invention relates to an apparatus and method for locating and positioning a medical device in a patient. The catheter based drug delivery device uses ultrasound imaging technology to facilitate tracking of the catheter as it is maneuvered through the body of a patient. The device includes a secondary body portion and a main body portion that are in signal communication with each other. Ultrasound signals generated from and received by the device are transmitted to an intravascular ultrasound (IVUS) system. An image of the structures surrounding and including the device is displayed on the IVUS system. A drug delivery needle, housed within the main body portion, can be precisely positioned at the target site using the ultrasound signals. This allows accurate delivery of drug to the target site and, thus, enhanced treatment capabilities.