Patents by Inventor Vinayak G. Gore
Vinayak G. Gore has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9162974Abstract: The present invention relates to an improved process for the preparation of the active pharmaceutical ingredient vorinostat. In particular it relates to a process for preparing vorinostat substantially free from impurities.Type: GrantFiled: October 6, 2014Date of Patent: October 20, 2015Assignee: Generics (UK) LimitedInventors: Vinayak G. Gore, Madhukar S. Patil, Rahul A. Bhalerao, Hemant M. Mande, Sandeep G. Mekde
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Publication number: 20150018424Abstract: The present invention relates to an improved process for the preparation of the active pharmaceutical ingredient vorinostat. In particular it relates to a process for preparing vorinostat substantially free from impurities.Type: ApplicationFiled: October 6, 2014Publication date: January 15, 2015Inventors: Vinayak G. Gore, Madhukar S. Patil, Rahul A. Bhalerao, Hemant M. Mande, Sandeep G. Mekde
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Patent number: 8883851Abstract: The present invention relates to an improved process for the preparation of the active pharmaceutical ingredient vorinostat. In particular it relates to a process for preparing vorinostat substantially free from impurities, involving suberic acid, aniline and hydroxylamine as starting materials.Type: GrantFiled: October 14, 2009Date of Patent: November 11, 2014Assignee: Generics [UK] LimitedInventors: Vinayak G. Gore, Madhukar S. Patil, Rahul A. Bhalerao, Hemant M. Mande, Sandeep G. Mekde
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Patent number: 8648214Abstract: The present invention relates to processes for the preparation of 4-hydroxy-??-[[[6-(4-phenylbutoxy)hexyl]amino]methyl]-1,3-benzenedimethanol 1-hydroxy-2-naphthoate (salmeterol xinafoate) (12a), the preparation of 4-hydroxy-??-[[[6-(4-phenylbutoxy)hexyl]amino]methyl]-1,3-benzenedimethanol (salmeterol) (11), the preparation of protected N-[6-(4-phenylbutoxy)hexyl]amine intermediates (7), and the preparation of 6-substituted (4-phenylbutoxy)hexane intermediates (5), shown below, wherein X is a leaving group and Pg is a protecting group.Type: GrantFiled: April 16, 2008Date of Patent: February 11, 2014Assignee: Generics [UK] LimitedInventors: Vinayak G. Gore, Avinash C. Gaikwad, Maheshkumar Gadakar, Vinay Kumar Shukla
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Patent number: 8344168Abstract: The present invention relates to a process for the preparation of steroidal 17?-carboxylic thioates. More particularly the present invention relates to a convenient and efficient synthesis of steroidal 17?-carboxylic thioates, such as fluticasone propionate I, using soluble mixed fluorides to introduce fluorine by displacing an appropriate leaving group X in compounds II resulting in selective and controlled fluorination. The present invention also relates to intermediates II and their preparation.Type: GrantFiled: December 8, 2008Date of Patent: January 1, 2013Assignee: Generics (UK) LimitedInventors: Vinayak G. Gore, Mahesh Gadakar, K. Pokharkar, V. Wakchure
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Patent number: 8119662Abstract: The present invention relates to a novel crystalline form of zofenopril calcium of formula (I), chemically known as (4S)-1-[(2S)-3-(benzoylthio)-2-methylpropionyl]-4-(phenylthio)-L-proline calcium salt. The present invention further relates to a process for the preparation of the new crystalline form of zofenopril calcium and its use in pharmaceutical preparations.Type: GrantFiled: December 20, 2007Date of Patent: February 21, 2012Assignee: Generics [UK] LimitedInventors: Vinayak G. Gore, Ashok D. Pehere, Avinash C. Gaikwad, Priyesh S. Vijaykar
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Publication number: 20110263712Abstract: The present invention relates to an improved process for the preparation of the active pharmaceutical ingredient vorinostat. In particular it relates to a process for preparing vorinostat substantially free from impurities, involving suberic acid, aniline and hydroxylamine as starting materials.Type: ApplicationFiled: October 14, 2009Publication date: October 27, 2011Applicant: Generics (UK) LimitedInventors: Vinayak G. Gore, Madhukar S. Patil, Rahul A. Bhalerao, Hemant M. Mande, Sandeep G. Mekde
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Publication number: 20110112157Abstract: The present invention relates to an improved process for the preparation of the active pharmaceutical ingredient zolmitriptan. In particular, it relates to an efficient process for the preparation of zolmitriptan and its pharmaceutically acceptable salts and solvates.Type: ApplicationFiled: October 3, 2008Publication date: May 12, 2011Applicant: GENERICS [UK] LIMITEDInventors: Debashish Datta, Vinayak G. Gore, Maheshkumar S. Gadakar, Kiran Pokharkar, Kiran Phatangare
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Publication number: 20110028736Abstract: The present invention relates to zofenopril calcium form A substantially free of other forms of zofenopril calcium and to zofenopril calcium having a chemical purity of more than 98.5%. The present invention also relates to methods of preparing such zofenopril calcium. It further relates to compositions comprising such zofenopril calcium.Type: ApplicationFiled: October 14, 2010Publication date: February 3, 2011Applicant: Generics [UK] LimitedInventors: Vinayak G. Gore, Ashok D. Pehere, Avinash C. Gaikwad, Priyesh S. Vijaykar
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Publication number: 20100256208Abstract: The present invention relates to a novel process for the preparation of rizatriptan and its pharmaceutically acceptable salts. It provides a novel process for the preparation of highly pure rizatriptan, which can be easily adopted for commercial production with a high degree of consistency in purity and yield. Subsequently the rizatriptan base prepared can be converted into any suitable pharmaceutically acceptable salt, such as the oxalate, succinate or benzoate salt, for dosage form preparation. The present invention also provides a composition comprising rizatriptan useful for the manufacture of a medicament for the treatment or prevention of migraine.Type: ApplicationFiled: June 4, 2008Publication date: October 7, 2010Inventors: Vinayak G. Gore, Vikas S. Kulkarni, Sneha R. Wavhal
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Publication number: 20100076086Abstract: The present invention relates to a novel process for the preparation of O-desmethyl venlafaxine (ODV).Type: ApplicationFiled: January 31, 2008Publication date: March 25, 2010Applicant: Merck Development Centre Private Limited Plot 1 A/2Inventor: Vinayak G. Gore
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Publication number: 20100063160Abstract: The present invention relates to crystalline forms of O-desmethyl venlafaxine (ODV) succinate monohydrate, namely Forms I and II, in pure form and to novel processes for their preparation. The present invention provides a process for the preparation of Form II free of Form I and a process for the preparation of Form I free of Form II. The present invention provides direct methods for the preparation of ODV succinate Form II from ODV free base and for the preparation of ODV succinate Form I from ODV free base.Type: ApplicationFiled: October 18, 2007Publication date: March 11, 2010Applicant: Merck Development Centre Private LimitedInventors: Vinayak G. Gore, Vikas S. Kulkarni, V.S. Wakchaure, M.G. Hublikar, S.R. Wavhal
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Publication number: 20100035994Abstract: The present invention relates to a novel hydrate form of O-desmethyl venlafaxine succinate. The present invention further relates to processes for the preparation of the novel hydrate form, pharmaceutical compositions comprising it, second medical uses of the novel hydrate form, and methods using it for treating diseases such as generalised anxiety disorder, anxiety, depressive disorder, depression and panic disorder.Type: ApplicationFiled: August 8, 2007Publication date: February 11, 2010Inventors: Vinayak G. Gore, Vikas S. Kulkarni, Vikas S. Wakchaure, Mahesh G. Hublikar, Sneha R. Wavhal
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Publication number: 20090198062Abstract: The present invention relates to a process for the preparation of bisphosphonic acids and salts thereof, in particular monosodium salts thereof. The invention also relates to the conversion of the bisphosphonic acids to their sodium salts using an aqueous-organic solvent system. The present invention further relates to the conversion of variable hydrate forms of risedronic acid monosodium salt into a pharmaceutically acceptable hemipentahydrate form by crystallization using an aqueous-organic solvent system.Type: ApplicationFiled: December 22, 2008Publication date: August 6, 2009Inventors: Vinayak G. Gore, Vinay Kumar Shukla, Manoj M. Ghadge, Rekha M. Avadhut
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Publication number: 20090177001Abstract: The present invention relates to a process for the preparation of steroidal 17?-carboxylic thioates. More particularly the present invention relates to a convenient and efficient synthesis of steroidal 17?-carboxylic thioates, such as fluticasone propionate I, using soluble mixed fluorides to introduce fluorine by displacing an appropriate leaving group X in compounds II resulting in selective and controlled fluorination. The present invention also relates to intermediates II and their preparation.Type: ApplicationFiled: December 8, 2008Publication date: July 9, 2009Inventors: Vinayak G. Gore, Mahesh Gadakar, K. Pokharkar, V. Wakchure
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Publication number: 20090176860Abstract: The present invention relates to zofenopril calcium form A substantially free of other forms of zofenopril calcium and to zofenopril calcium having a chemical purity of more than 98.5%. The present invention also relates to methods of preparing such zofenopril calcium. It further relates to compositions comprising such zofenopril calcium.Type: ApplicationFiled: November 25, 2008Publication date: July 9, 2009Inventors: Vinayak G. Gore, Ashok D. Pehere, Avinash C. Gaikwad, Priyesh S. Vijaykar
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Publication number: 20080262267Abstract: The present invention relates to processes for the preparation of 4-hydroxy-??-[[[6-(4-phenylbutoxy)hexyl]amino]methyl]-1,3-benzenedimethanol 1-hydroxy-2-naphthoate (salmeterol xinafoate) (12a), the preparation of 4-hydroxy-??-[[[6-(4-phenylbutoxy)hexyl]amino]methyl]-1,3-benzenedimethanol (salmeterol) (11), the preparation of protected N-[6-(4-phenylbutoxy)hexyl]amine intermediates (7), and the preparation of 6-substituted (4-phenylbutoxy)hexane intermediates (5), shown below, wherein X is a leaving group and Pg is a protecting group.Type: ApplicationFiled: April 16, 2008Publication date: October 23, 2008Applicant: Generics [UK] LimitedInventors: Vinayak G. Gore, Avinash C. Gaikwad, M. Gadkar, V.K. Shukla
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Publication number: 20080182888Abstract: The present invention relates to a novel crystalline form of zofenopril calcium of formula (I), chemically known as (4S)-1-[(2S)-3-(benzoylthio)-2-methylpropionyl]-4-(phenylthio)-L-proline calcium salt. The present invention further relates to a process for the preparation of the new crystalline form of zofenopril calcium and its use in pharmaceutical preparations.Type: ApplicationFiled: December 20, 2007Publication date: July 31, 2008Inventors: Vinayak G. Gore, Ashok D. Pehere, Avinash C. Gaikwad, Priyesh S. Vijaykar
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Patent number: 7091327Abstract: The present invention relates to a process for the preparation of aromatic azo-compounds, in particular 3,3?-azo-bis(6-hydroxybenzoic acid) (olsalazine) and its salts and derivatives.Type: GrantFiled: September 17, 2003Date of Patent: August 15, 2006Assignee: Generics [UK] LimitedInventors: Vinayak G. Gore, Manoj M. Ghadge, Vishakha R. Shembekar, R. Venkat Raman
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Publication number: 20040132982Abstract: The present invention relates to a process for the preparation of aromatic azo-compounds, in particular 3,3′-azo-bis(6-hydroxybenzoic acid) (olsalazine) and its salts and derivatives.Type: ApplicationFiled: September 17, 2003Publication date: July 8, 2004Applicant: Generics [UK] LimitedInventors: Vinayak G. Gore, Manoj M. Ghadge, Vishakha R. Shembekar, R. Venkat Raman