Patents by Inventor Vinayak V. Kane

Vinayak V. Kane has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Synthesis of deoxyzoapatanol derivatives
    Patent number: 4384126
    Abstract: A method for the synthesis of derivatives of deoxyzoapatanol is described. The derivatives are effective as post-implantive contragestational agents.
    Type: Grant
    Filed: February 12, 1982
    Date of Patent: May 17, 1983
    Assignee: Ortho Pharmaceutical Corporation
    Inventor: Vinayak V. Kane
  • Total synthesis of the utero-evacuant substance d,l-zoapatanol
    Patent number: 4296035
    Abstract: A method for the synthesis of racemic 2S* 3R*-6E-(2"-hydroxyethylidene)-2-methyl-2-(4',8'-dimethyl-5'-oxo-7'-nonenyl )-oxepan-3-ol is described. The naturally occurring product, 2S,3R-6E-(2"-hydroxyethylidene)-2-methyl-2-(4',8'-dimethyl-5'-oxo-7'-nonen yl)-oxepan-3-ol, is one of the active components of the zoapatle plant.
    Type: Grant
    Filed: March 17, 1980
    Date of Patent: October 20, 1981
    Assignee: Ortho Pharmaceutical Corporation
    Inventor: Vinayak V. Kane
  • Method of treating arrhythmia
    Patent number: 4250180
    Abstract: Azabicyclic compounds are prepared by reaction of a diene and a diazenediyl compound. The azabicyclic compounds possess cardiovascular activity particularly as antiarrhythmic agents.
    Type: Grant
    Filed: July 16, 1979
    Date of Patent: February 10, 1981
    Assignee: Ortho Pharmaceutical Corporation
    Inventors: Vinayak V. Kane, Seymour D. Levine
  • Total synthesis of the utero-evacuant substance d,l-zoapatanol
    Patent number: 4239689
    Abstract: A method for the synthesis of racemic 2S*, 3R*-6E-(2"-hydroxyethylidene)-2-methyl-2-(4',8'-dimethyl-5'-oxo-7'-nonenyl )-oxepan-3-ol is described. The naturally occurring product, 2S, 3R-6E-(2"-hydroxyethylidene)-2-methyl-2-(4',8'-dimethyl-5'-oxo-7'-nonenyl) -oxepan-3-ol, is one of the active components of the zoapatle plant.
    Type: Grant
    Filed: December 18, 1978
    Date of Patent: December 16, 1980
    Assignee: Ortho Pharmaceutical Corporation
    Inventor: Vinayak V. Kane
  • Total synthesis of the utero-evacuant substance d,l-zoapatanol
    Patent number: 4237053
    Abstract: A method for the synthesis of racemic 2S*,3R*-6E-(2"-hydroxyethylidene)-2-methyl-2-(4',8'-dimethyl-5'-oxo-7'-non enyl)-oxepan-3-ol is described. The naturally occurring product, 2S,3R-6E-(2"-hydroxyethylidene)-2-methyl-2-(4',8'-dimethyl-5'-oxo-7'-nonen yl)-oxepan-3-ol, is one of the active components of the zoapatle plant.
    Type: Grant
    Filed: December 20, 1978
    Date of Patent: December 2, 1980
    Assignee: Ortho Pharmaceutical Corporation
    Inventor: Vinayak V. Kane
  • Method for reacting 2-aromatic substituted 1,3-dithianes with .alpha.,.beta .
    Patent number: 4089876
    Abstract: Method for reacting a 2-aromatic substituted 1,3-dithiane with an .alpha.,.beta.-unsaturated ketone to selectively produce either the 1,4-addition product or the 1,2-addition product and the products made thereby. The 1,2- and 1,4-addition products possess cardiovascular activity, particularly antihypertensive and antiarrythmic activity.
    Type: Grant
    Filed: July 23, 1976
    Date of Patent: May 16, 1978
    Assignee: Ortho Pharmaceutical Corporation
    Inventor: Vinayak V. Kane
  • Azabicyclic compounds, and production thereof
    Patent number: 4057547
    Abstract: Novel azabicyclic compounds useful for their central nervous system depressant and cardiovascular activity, methods for preparing same, and intermediates.
    Type: Grant
    Filed: February 2, 1976
    Date of Patent: November 8, 1977
    Assignee: Ortho Pharmaceutical Corporation
    Inventors: Seymour Levine, Vinayak V. Kane
  • Indane tetrol amines
    Patent number: 4022788
    Abstract: The compounds of the invention have the formula ##STR1## wherein Y is a radical of the formula ##STR2## or of the formula ##STR3## wherein (CH.sub.2) is a straight or branched chain alkyl radical, n is 1-6, m is 0 or 1 and R.sup.5 and R.sup.6 may be the same or different and may be hydrogen, alkyl, arylalkyl, and R.sup.5 and R.sup.6 together with the nitrogen to which they are attached may be pyrrolidino, piperadino or N'-alkyl piperazino;R.sup.1, r.sup.2, r.sup.3 or R.sup.4 may be the same or different and may be hydrogen; alkyl, trifluoromethyl; alkanoyl; haloalkanoyl; alkoxycarbonyl of the formula ##STR4## wherein R is an alkyl radical; alkoxyalkyl; aminoalkanoyl of the formula ##STR5## wherein R.sup.5 and R.sup.6 are as previously defined and p is 0-3; 2-, 3-, or 4-pyridylcarbonyl; phenyl; monosubstituted phenyl wherein the substituent is alkyl, alkoxy, hydroxy, nitro, amino, or dialkylamino; alkenoyl; or aroyl;R.sup.7 and R.sup.8 may be the same or different and may be hydrogen or alkyl, and R.sup.
    Type: Grant
    Filed: April 23, 1975
    Date of Patent: May 10, 1977
    Assignee: E. R. Squibb & Sons, Inc.
    Inventors: Frederic Peter Hauck, Joyce Reid, Vinayak V. Kane