Patents by Inventor Vincent A. Boyd

Vincent A. Boyd has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210188777
    Abstract: In one aspect, compounds and compositions that modulate a bromodomain and methods of making and using same are disclosed. The disclosed compounds and compositions can be useful for disorders associated with inhibition of a bromodomain such as, for example, cancer. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Application
    Filed: March 4, 2021
    Publication date: June 24, 2021
    Inventors: R. Kip Guy, P. Jake Slavish, William Robert Shadrick, Brandon M. Young, Vincent A. Boyd, Nagakumar Bharatham, Jeanine E. Price, Anang Shelat
  • Patent number: 11028051
    Abstract: In one aspect, compounds and compositions that modulate a bromodomain and methods of making and using same are disclosed. The disclosed compounds and compositions can be useful for disorders associated with inhibition of a bromodomain such as, for example, cancer. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Grant
    Filed: December 12, 2017
    Date of Patent: June 8, 2021
    Assignee: St. Jude Children's Research Hospital
    Inventors: R. Kip Guy, P. Jake Slavish, William Robert Shadrick, Brandon M. Young, Vincent A. Boyd, Nagakumar Bharatham, Jeanine E. Price, Anang Shelat
  • Patent number: 10875875
    Abstract: Provided herein are compounds and pharmaceutical compositions of formula I where R1, R2, R3, R4, R5 and R6 are as described herein. Also provided pharmaceutically acceptable salts or stereoisomers of these compounds. In addition methods are provided for inhibiting the binding of an integrin to treat various pathophysiological conditions.
    Type: Grant
    Filed: April 26, 2017
    Date of Patent: December 29, 2020
    Assignee: Aviara Pharmaceuticals, Inc.
    Inventors: Ronald J. Biediger, Michele A. Benish, Lindsay Bonner Hardy, Vincent A. Boyd, Robert V. Market, Thomas P. Thrash, Brandon M. Young
  • Publication number: 20200079739
    Abstract: In one aspect, compounds and compositions that modulate a bromodomain and methods of making and using same are disclosed. The disclosed compounds and compositions can be useful for disorders associated with inhibition of a bromodomain such as, for example, cancer. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Application
    Filed: December 12, 2017
    Publication date: March 12, 2020
    Inventors: R. Kip Guy, P. Jake Slavish, William Robert Shadrick, Brandon M. Young, Vincent A. Boyd, Nagakumar Bharatham, Jeanine E. Price, Anang Shelat
  • Publication number: 20180312523
    Abstract: Provided herein are compounds and pharmaceutical compositions of formula I where R1, R2, R3, R4, R5 and R6 are as described herein. Also provided pharmaceutically acceptable salts or stereoisomers of these compounds. In addition methods are provided for inhibiting the binding of an integrin to treat various pathophysiological conditions.
    Type: Application
    Filed: April 26, 2017
    Publication date: November 1, 2018
    Applicant: Aviara Pharmaceuticals, Inc.
    Inventors: Ronald J. Biediger, Michele A. Benish, Lindsay Bonner Hardy, Vincent A. Boyd, Robert V. Market, Thomas P. Thrash, Brandon M. Young
  • Patent number: 9328075
    Abstract: In one aspect, the invention relates to novel, broad-spectrum anti-viral, pyrimidinone compounds, methods of use, compositions and kits useful in treating and/or preventing influenza. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Grant
    Filed: May 5, 2012
    Date of Patent: May 3, 2016
    Assignee: St. Jude Children's Research Hospital
    Inventors: Thomas R. Webb, Vincent A. Boyd
  • Publication number: 20140079666
    Abstract: In one aspect, the invention relates to novel, broad-spectrum anti-viral, pyrimidinone compounds, methods of use, compositions and kits useful in treating and/or preventing influenza. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Application
    Filed: May 5, 2012
    Publication date: March 20, 2014
    Applicant: ST. JUDE CHILDREN'S RESEARCH HOSPITAL
    Inventors: Thomas R. Webb, Vincent A. Boyd
  • Patent number: 7868135
    Abstract: The present invention provides derivatives of lipopeptide antibiotics that display antimicrobial activity against microorganisms, methods and compounds for synthesizing such antimicrobial derivatives and analogues, and methods of using the compounds in a variety of contexts, including in the treatment and prevention of microbial infections.
    Type: Grant
    Filed: June 28, 2004
    Date of Patent: January 11, 2011
    Assignee: Biowest Therapeutics Inc.
    Inventors: Dale R. Cameron, Vincent A. Boyd, Richard A. Leese, William V. Curran, Donald B. Borders, Paulo W. M. Sgarbi, Shirley A. Wacowich-Sgarbi, Matthew Nodwell, Yuchen Chen, Qi Jia, Dominique Dugourd
  • Publication number: 20100137199
    Abstract: The present invention provides Dab9 derivatives of amphomycin-type lipopeptide antibiotics that display antimicrobial activity against Gram-positive bacteria, methods and intermediates for synthesizing the compounds and methods of using the compounds in a variety of contexts, including in the treatment and prevention of infections.
    Type: Application
    Filed: February 1, 2010
    Publication date: June 3, 2010
    Applicant: Migenix Inc.
    Inventors: Maria Fardis, Dale R. Cameron, Vincent A. Boyd
  • Patent number: 7655623
    Abstract: The present invention provides Dab9 derivatives of amphomycin-type lipopepetide antibiotics that display antimicrobial activity against Gram-positive bacteria, methods and intermediates for synthesizing the compounds and methods of using the compounds in a variety of contexts, including in the treatment and prevention of infections.
    Type: Grant
    Filed: October 5, 2006
    Date of Patent: February 2, 2010
    Assignee: Migenix Inc.
    Inventors: Maria Fardis, Dale R. Cameron, Vincent A. Boyd
  • Publication number: 20070167357
    Abstract: The present invention provides Dab9 derivatives of amphomycin-type lipopepetide antibiotics that display antimicrobial activity against Gram-positive bacteria, methods and intermediates for synthesizing the compounds and methods of using the compounds in a variety of contexts, including in the treatment and prevention of infections.
    Type: Application
    Filed: October 5, 2006
    Publication date: July 19, 2007
    Inventors: Maria Fardis, Dale Cameron, Vincent Boyd
  • Publication number: 20070021434
    Abstract: The present dislcosure provides amide-based, non-nucleoside compounds having antiviral activity against Hepacivirus, such as hepatitis C virus (HCV), methods and intermediates for synthesizing such compounds, and methods of using the compounds in a variety of contexts, including in the treatment and prevention of viral infections. The present dislcosure also provides methods for identifying amide-based, non-nucleoside compounds having antiviral activity.
    Type: Application
    Filed: June 26, 2006
    Publication date: January 25, 2007
    Applicant: Migenix Inc.
    Inventors: Vincent Boyd, Dale Cameron, Qi Jia, Paulo Sgarbi, Shirley Wacowich-Sgarbi
  • Patent number: 7125844
    Abstract: The present invention provides Dab9 derivatives of amphomycin-type lipopeptide antibiotics that display antimicrobial activity against Gram-positive bacteria, methods and intermediates for synthesizing such compounds, and methods of using the compounds in a variety of contexts, including in the treatment and prevention of infections.
    Type: Grant
    Filed: January 2, 2003
    Date of Patent: October 24, 2006
    Assignee: Migenix Inc.
    Inventors: Maria Fardis, Dale R. Cameron, Vincent A. Boyd
  • Publication number: 20050153876
    Abstract: The present invention provides derivatives of lipopeptide antibiotics that display antimicrobial activity against microorganisms, methods and compounds for synthesizing such antimicrobial derivatives and analogues, and methods of using the compounds in a variety of contexts, including in the treatment and prevention of microbial infections.
    Type: Application
    Filed: June 28, 2004
    Publication date: July 14, 2005
    Applicant: Migenix Inc.
    Inventors: Dale Cameron, Vincent Boyd, Richard Leese, William Curran, Donald Borders, Paulo Sgarbi, Shirley Wacowich-Sgarbi, Mathew Nodwell, Yuchen Chen, Qi Jia, Dominique Dugourd
  • Publication number: 20040138107
    Abstract: The present invention provides Dab9 derivatives of amphomycin-type lipopeptide antibiotics that display antimicrobial activity against Gram-positive bacteria, methods and intermediates for synthesizing such compounds, and methods of using the compounds in a variety of contexts, including in the treatment and prevention of infections.
    Type: Application
    Filed: January 2, 2003
    Publication date: July 15, 2004
    Applicant: Micrologix Biotech Inc.
    Inventors: Maria Fardis, Dale R. Cameron, Vincent A. Boyd
  • Patent number: 6329378
    Abstract: Disclosed are pharmaceutical compositions comprising aryl and heteroaryl hydrazone, hydrazine and thiosemicarbazone derivatives of formulae I and II, and methods for using the compositions as antifungal agents. The invention also relates to novel aryl and heteroaryl hydrazone, hydrazine and thiosemicarbazone derivatives of formulae I and II, their preparation, to pharmaceutical compositions containing them, and to methods of using them to alleviate fungal infections.
    Type: Grant
    Filed: February 10, 2000
    Date of Patent: December 11, 2001
    Assignee: Anadys Pharmaceuticals, Inc.
    Inventors: Xiaodan Mei, Peng Wang, Andrei Caracoti, Pamela Mingo, Vincent Boyd, Robert Murray, Nicholas J. Sisti, Yi Bin Xiang, Shuhao Zhu, C. Richard Wobbe, Daniel Moore
  • Patent number: 6274596
    Abstract: Disclosed are pharmaceutical compositions and formulations comprising benzoquinoline derivatives having the formula (I) to (V), wherein formula (I) is: X is selected from the group consisting of O, S, CH2, CH2-CH2, C═O or NRB; Y is C or N; R1, R2, R3 and R4 are independently selected from the group consisting of hydrogen, halogen, linear or branched chain lower alky, alkenyl, alkynyl, alkoxy or acyl; X-RA and R3, or R3 and R4, are optionally linked together to form a C3-C4 alkylene bridge, where X is CH2 or C═O; provided that: when X is NRB, then (a) RB is hydrogen, and RA is a linear or branched chain lower alkyl, aryl, heteroaryl, cycloalkyl or cycloalkenyl optionally interrupted by at least one heteroatom, said alkyl, alkenyl, alkynyl, aryl, heteroaryl, cycloalkyl or cycloalkenyl being optionally substituted singly or plurally by at least one of a linear or branched chain lower alkyl, alkenyl, alkynyl, acyl, alkoxy, or cycloalkyl optionally interrupted by at least one heter
    Type: Grant
    Filed: October 6, 1999
    Date of Patent: August 14, 2001
    Assignee: Anadys Pharmaceuticals, Inc.
    Inventors: Kelvin Lam, Vincent Boyd, Yi Bin Xiang