Patents by Inventor Vincent A. Boyd

Vincent A. Boyd has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Tetrahydroquinoline-based bromodomain inhibitors
    Patent number: 11787768
    Abstract: In one aspect, compounds and compositions that modulate a bromodomain and methods of making and using same are disclosed. The disclosed compounds and compositions can be useful for disorders associated with inhibition of a bromodomain such as, for example, cancer. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Grant
    Filed: March 4, 2021
    Date of Patent: October 17, 2023
    Assignee: ST. JUDE CHILDREN'S RESEARCH HOSPITAL
    Inventors: R. Kip Guy, P Jake Slavish, William Robert Shadrick, Brandon M. Young, Vincent A. Boyd, Nagakumar Bharatham, Jeanine E. Price, Anang Shelat
  • TETRAHYDROQUINOLINE-BASED BROMODOMAIN INHIBITORS
    Publication number: 20210188777
    Abstract: In one aspect, compounds and compositions that modulate a bromodomain and methods of making and using same are disclosed. The disclosed compounds and compositions can be useful for disorders associated with inhibition of a bromodomain such as, for example, cancer. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Application
    Filed: March 4, 2021
    Publication date: June 24, 2021
    Inventors: R. Kip Guy, P. Jake Slavish, William Robert Shadrick, Brandon M. Young, Vincent A. Boyd, Nagakumar Bharatham, Jeanine E. Price, Anang Shelat
  • Tetrahydroquinoline-based bromodomain inhibitors
    Patent number: 11028051
    Abstract: In one aspect, compounds and compositions that modulate a bromodomain and methods of making and using same are disclosed. The disclosed compounds and compositions can be useful for disorders associated with inhibition of a bromodomain such as, for example, cancer. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Grant
    Filed: December 12, 2017
    Date of Patent: June 8, 2021
    Assignee: St. Jude Children's Research Hospital
    Inventors: R. Kip Guy, P. Jake Slavish, William Robert Shadrick, Brandon M. Young, Vincent A. Boyd, Nagakumar Bharatham, Jeanine E. Price, Anang Shelat
  • Propionic acid derivatives and methods of use thereof
    Patent number: 10875875
    Abstract: Provided herein are compounds and pharmaceutical compositions of formula I where R1, R2, R3, R4, R5 and R6 are as described herein. Also provided pharmaceutically acceptable salts or stereoisomers of these compounds. In addition methods are provided for inhibiting the binding of an integrin to treat various pathophysiological conditions.
    Type: Grant
    Filed: April 26, 2017
    Date of Patent: December 29, 2020
    Assignee: Aviara Pharmaceuticals, Inc.
    Inventors: Ronald J. Biediger, Michele A. Benish, Lindsay Bonner Hardy, Vincent A. Boyd, Robert V. Market, Thomas P. Thrash, Brandon M. Young
  • TETRAHYDROQUINOLINE-BASED BROMODOMAIN INHIBITORS
    Publication number: 20200079739
    Abstract: In one aspect, compounds and compositions that modulate a bromodomain and methods of making and using same are disclosed. The disclosed compounds and compositions can be useful for disorders associated with inhibition of a bromodomain such as, for example, cancer. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Application
    Filed: December 12, 2017
    Publication date: March 12, 2020
    Inventors: R. Kip Guy, P. Jake Slavish, William Robert Shadrick, Brandon M. Young, Vincent A. Boyd, Nagakumar Bharatham, Jeanine E. Price, Anang Shelat
  • Propionic Acid Derivatives and Methods of Use Thereof
    Publication number: 20180312523
    Abstract: Provided herein are compounds and pharmaceutical compositions of formula I where R1, R2, R3, R4, R5 and R6 are as described herein. Also provided pharmaceutically acceptable salts or stereoisomers of these compounds. In addition methods are provided for inhibiting the binding of an integrin to treat various pathophysiological conditions.
    Type: Application
    Filed: April 26, 2017
    Publication date: November 1, 2018
    Applicant: Aviara Pharmaceuticals, Inc.
    Inventors: Ronald J. Biediger, Michele A. Benish, Lindsay Bonner Hardy, Vincent A. Boyd, Robert V. Market, Thomas P. Thrash, Brandon M. Young
  • Pyrimidinone compounds and methods for treating influenza
    Patent number: 9328075
    Abstract: In one aspect, the invention relates to novel, broad-spectrum anti-viral, pyrimidinone compounds, methods of use, compositions and kits useful in treating and/or preventing influenza. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Grant
    Filed: May 5, 2012
    Date of Patent: May 3, 2016
    Assignee: St. Jude Children's Research Hospital
    Inventors: Thomas R. Webb, Vincent A. Boyd
  • PYRIMIDINONE COMPOUNDS AND METHODS FOR PREVENTING AND TREATING INFLUENZA
    Publication number: 20140079666
    Abstract: In one aspect, the invention relates to novel, broad-spectrum anti-viral, pyrimidinone compounds, methods of use, compositions and kits useful in treating and/or preventing influenza. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Application
    Filed: May 5, 2012
    Publication date: March 20, 2014
    Applicant: ST. JUDE CHILDREN'S RESEARCH HOSPITAL
    Inventors: Thomas R. Webb, Vincent A. Boyd
  • Compositions of lipopeptide antibiotic derivatives and methods of use thereof
    Patent number: 7868135
    Abstract: The present invention provides derivatives of lipopeptide antibiotics that display antimicrobial activity against microorganisms, methods and compounds for synthesizing such antimicrobial derivatives and analogues, and methods of using the compounds in a variety of contexts, including in the treatment and prevention of microbial infections.
    Type: Grant
    Filed: June 28, 2004
    Date of Patent: January 11, 2011
    Assignee: Biowest Therapeutics Inc.
    Inventors: Dale R. Cameron, Vincent A. Boyd, Richard A. Leese, William V. Curran, Donald B. Borders, Paulo W. M. Sgarbi, Shirley A. Wacowich-Sgarbi, Matthew Nodwell, Yuchen Chen, Qi Jia, Dominique Dugourd
  • Dab9 DERIVATIVES OF LIPOPEPTIDE ANTIBIOTICS AND METHODS OF MAKING AND USING THE SAME
    Publication number: 20100137199
    Abstract: The present invention provides Dab9 derivatives of amphomycin-type lipopeptide antibiotics that display antimicrobial activity against Gram-positive bacteria, methods and intermediates for synthesizing the compounds and methods of using the compounds in a variety of contexts, including in the treatment and prevention of infections.
    Type: Application
    Filed: February 1, 2010
    Publication date: June 3, 2010
    Applicant: Migenix Inc.
    Inventors: Maria Fardis, Dale R. Cameron, Vincent A. Boyd
  • Dabderivatives of lipopeptide antibiotics and methods of making and using the same
    Patent number: 7655623
    Abstract: The present invention provides Dab9 derivatives of amphomycin-type lipopepetide antibiotics that display antimicrobial activity against Gram-positive bacteria, methods and intermediates for synthesizing the compounds and methods of using the compounds in a variety of contexts, including in the treatment and prevention of infections.
    Type: Grant
    Filed: October 5, 2006
    Date of Patent: February 2, 2010
    Assignee: Migenix Inc.
    Inventors: Maria Fardis, Dale R. Cameron, Vincent A. Boyd
  • Dabderivatives of lipopeptide antibiotics and methods of making and using the same
    Patent number: 7125844
    Abstract: The present invention provides Dab9 derivatives of amphomycin-type lipopeptide antibiotics that display antimicrobial activity against Gram-positive bacteria, methods and intermediates for synthesizing such compounds, and methods of using the compounds in a variety of contexts, including in the treatment and prevention of infections.
    Type: Grant
    Filed: January 2, 2003
    Date of Patent: October 24, 2006
    Assignee: Migenix Inc.
    Inventors: Maria Fardis, Dale R. Cameron, Vincent A. Boyd
  • Dab9 derivatives of lipopeptide antibiotics and methods of making and using the same
    Publication number: 20040138107
    Abstract: The present invention provides Dab9 derivatives of amphomycin-type lipopeptide antibiotics that display antimicrobial activity against Gram-positive bacteria, methods and intermediates for synthesizing such compounds, and methods of using the compounds in a variety of contexts, including in the treatment and prevention of infections.
    Type: Application
    Filed: January 2, 2003
    Publication date: July 15, 2004
    Applicant: Micrologix Biotech Inc.
    Inventors: Maria Fardis, Dale R. Cameron, Vincent A. Boyd