Patents by Inventor Vincent A. Gruber

Vincent A. Gruber has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200188459
    Abstract: Compositions comprising metabolized conditioned growth medium and/or metabolized cell extract and methods of use are described. The metabolized conditioned growth medium and metabolized cell extract compositions may be formulated with an acceptable carrier into injectable or topical formulations, for example, as a cream, lotion or gel, and may be used in cosmeceutical or pharmaceutical applications. The metabolized conditioned growth medium and metabolized cell extract may also be further processed to concentrate or reduce one or more factors or components contained within the metabolized conditioned growth medium or metabolized cell extract. The growth medium may be conditioned by any eukaryotic cell. The metabolized conditioned growth medium and metabolized cell extract may be used to prevent or treat a condition, for example, a skin condition.
    Type: Application
    Filed: February 4, 2020
    Publication date: June 18, 2020
    Inventors: James Vincent Gruber, Smitha Rao, Rahul Mehta, Sujatha D. Sonti
  • Publication number: 20190175672
    Abstract: Compositions comprising metabolized conditioned growth medium and/or metabolized cell extract and methods of use are described. The metabolized conditioned growth medium and metabolized cell extract compositions may be formulated with an acceptable carrier into injectable or topical formulations, for example, as a cream, lotion or gel, and may be used in cosmeceutical or pharmaceutical applications. The metabolized conditioned growth medium and metabolized cell extract may also be further processed to concentrate or reduce one or more factors or components contained within the metabolized conditioned growth medium or metabolized cell extract. The growth medium may be conditioned by any eukaryotic cell. The metabolized conditioned growth medium and metabolized cell extract may be used to prevent or treat a condition, for example, a skin condition.
    Type: Application
    Filed: February 15, 2019
    Publication date: June 13, 2019
    Inventors: James Vincent Gruber, Smitha Rao, Rahul Mehta, Sujatha D. Sonti
  • Patent number: 10285933
    Abstract: A personal care composition includes an ozone-stressed yeast lysate; and a preservative, in which the preservative is selected from phenoxyethanol, isopropyl alcohol, benzyl alcohol, propylene glycol, butylene glycol, pentylene glycol, methylparaben, propylparaben, butylparaben, benzalkonium chloride, Quaternium 15, methylisothiazolinone, methylchloroisothiazolinone, DMDM hydantoin, imidazolidinyl urea, diazolidinyl urea, butylated hydroxytoluene, tocopherol, triclosan, chlorohexidine digluconate, and combinations thereof, and the ozone-stressed yeast lysate is produced by a method including exposing growing yeast to ozone by aerating the yeast for a time period of between five minutes and seventy-two hours with an aeration gas having an ozone concentration of from 0.0001 millimolar (mM) to 1.
    Type: Grant
    Filed: August 12, 2016
    Date of Patent: May 14, 2019
    Assignee: ARCH PERSONAL CARE PRODUCTS L.P.
    Inventor: James Vincent Gruber
  • Patent number: 10272121
    Abstract: Disclosed herein is a topical composition that contains a fermentation extract from a simultaneous or sequential fermentation. When topically applied to skin, the composition of the invention is effective in stimulating the production of hyaluronic acid, CD44 and Caspase 14 protein in skin cells.
    Type: Grant
    Filed: October 25, 2012
    Date of Patent: April 30, 2019
    Assignee: ARCH PERSONAL CARE PRODUCT, LP
    Inventors: Smitha Rao, James Vincent Gruber
  • Publication number: 20190054325
    Abstract: Disclosed herein is a topical composition that contains (a) a plant meristem conditioned nutrient medium derived from the plants of the genus Oryza; (b) a preservative present at an amount sufficient to provide sterilizing or biostatic efficacy with respect to component (a); and (c) a dermatologically acceptable vehicle. When topically applied to mammalian cells, the composition of the invention can influence the epigenetic methylation of the DNA such that the methylation state is modulated to have more characteristics and patterns of the epigenetic state of younger cells.
    Type: Application
    Filed: October 22, 2018
    Publication date: February 21, 2019
    Inventors: Philip Ledette LUDWIG, James Vincent Gruber
  • Patent number: 10206961
    Abstract: Compositions comprising metabolized conditioned growth medium and/or metabolized cell extract and methods of use are described. The metabolized conditioned growth medium and metabolized cell extract compositions may be formulated with an acceptable carrier into injectable or topical formulations, for example, as a cream, lotion or gel, and may be used in cosmeceutical or pharmaceutical applications. The metabolized conditioned growth medium and metabolized cell extract may also be further processed to concentrate or reduce one or more factors or components contained within the metabolized conditioned growth medium or metabolized cell extract. The growth medium may be conditioned by any eukaryotic cell. The metabolized conditioned growth medium and metabolized cell extract may be used to prevent or treat a condition, for example, a skin condition.
    Type: Grant
    Filed: October 7, 2013
    Date of Patent: February 19, 2019
    Assignee: Allergan, Inc.
    Inventors: James Vincent Gruber, Smitha Rao, Rahul Mehta, Sujatha D. Sonti
  • Patent number: 9901538
    Abstract: A method of producing yeast-polyphenol ferment extract includes growing the cells of a yeast of pichia genus in a growth media to late-logarithmic growth phase, in which the carbon source in the media is exhausted; exposing the cells to a non-cytotoxic dose of polyphenol; and extracting cytoplasmic and extra-cellular components of the exposed yeast cells from the growth media.
    Type: Grant
    Filed: July 12, 2017
    Date of Patent: February 27, 2018
    Assignee: ARCH PERSONAL CARE PRODUCTS, L.P.
    Inventors: Smitha Rao, James Vincent Gruber, Geoffrey Jamison Brooks
  • Publication number: 20170319469
    Abstract: A method of producing yeast-polyphenol ferment extract includes growing the cells of a yeast of pichia genus in a growth media to late-logarithmic growth phase, in which the carbon source in the media is exhausted; exposing the cells to a non-cytotoxic dose of polyphenol; and extracting cytoplasmic and extra-cellular components of the exposed yeast cells from the growth media.
    Type: Application
    Filed: July 12, 2017
    Publication date: November 9, 2017
    Inventors: SMITHA RAO, JAMES VINCENT GRUBER, GEOFFREY JAMISON BROOKS
  • Patent number: 9744381
    Abstract: Disclosed herein is a composition that is suitable for influencing electromagnetic radiation on cutaneous extracellular matrix protein production. The composition contains (a) a proanthrocyanin, a polyphenol or a proanthrocyanin/polyphenol-containing plant extract, absorbed or adsorbed onto an inert carrier, where component (a) is responsive to UV, IR or visible light; (b) a photo-activatable amino acid or amino acids blend; and (c) a dermatologically-acceptable vehicle, wherein component (a) is present in an amount of from about 15 wt % to about 35 wt % based on the total amount of component (a) and component (b), said component (b) is present in an amount of from about 65 wt % to about 85 wt % based on the total amount of component (a) and component (b), and said component (c) is present in an amount of from about 90 wt % to about 99.95 wt % based on the total weight of the composition.
    Type: Grant
    Filed: March 21, 2012
    Date of Patent: August 29, 2017
    Assignee: ARCH CHEMICALS, INC.
    Inventors: David Dru Horinek, James Vincent Gruber, Vito Thomas Cataldo, Robert Michael Klein
  • Patent number: 9744121
    Abstract: A method of producing yeast-polyphenol ferment extract includes growing the cells of a yeast of pichia genus in a growth media to late-logarithmic growth phase, in which the carbon source in the media is exhausted; exposing the cells to a non-cytotoxic dose of polyphenol; and extracting cytoplasmic and extra-cellular components of the exposed yeast cells from the growth media.
    Type: Grant
    Filed: May 27, 2016
    Date of Patent: August 29, 2017
    Assignee: ARCH PERSONAL CARE PRODUCTS, L.P.
    Inventors: Smitha Rao, James Vincent Gruber, Geoffrey Jamison Brooks
  • Publication number: 20160346195
    Abstract: A personal care composition includes an ozone-stressed yeast lysate; and a preservative, in which the preservative is selected from phenoxyethanol, isopropyl alcohol, benzyl alcohol, propylene glycol, butylene glycol, pentylene glycol, methylparaben, propylparaben, butylparaben, benzalkonium chloride, Quaternium 15, methylisothiazolinone, methylchloroisothiazolinone, DMDM hydantoin, imidazolidinyl urea, diazolidinyl urea, butylated hydroxytoluene, tocopherol, triclosan, chlorohexidine digluconate, and combinations thereof, and the ozone-stressed yeast lysate is produced by a method including exposing growing yeast to ozone by aerating the yeast for a time period of between five minutes and seventy-two hours with an aeration gas having an ozone concentration of from 0.0001 millimolar (mM) to 1.
    Type: Application
    Filed: August 12, 2016
    Publication date: December 1, 2016
    Inventor: James Vincent GRUBER
  • Publication number: 20160317433
    Abstract: A method for preparing and using the of producing yeast-polyphenol ferment extract includes growing the cells of a yeast of pichia genus in a growth media to late-logarithmic growth phase, in which the carbon source in the media is exhausted; exposing the cells to a non-cytotoxic dose of polyphenol; and extracting cytoplasmic and extra-cellular components of the exposed yeast cells from the growth media.
    Type: Application
    Filed: May 27, 2016
    Publication date: November 3, 2016
    Inventors: SMITHA RAO, JAMES VINCENT GRUBER, GEOFFREY JAMISON BROOKS
  • Patent number: 9408881
    Abstract: Compositions comprising metabolized conditioned growth medium and/or metabolized cell extract and methods of use are described. The metabolized conditioned growth medium and metabolized cell extract compositions may be formulated with an acceptable carrier into injectable or topical formulations, for example, as a cream, lotion or gel, and may be used in cosmeceutical or pharmaceutical applications. The metabolized conditioned growth medium and metabolized cell extract may also be further processed to concentrate or reduce one or more factors or components contained within the metabolized conditioned growth medium or metabolized cell extract. The growth medium may be conditioned by any eukaryotic cell. The metabolized conditioned growth medium and metabolized cell extract may be used to prevent or treat a condition, for example, a skin condition.
    Type: Grant
    Filed: November 11, 2011
    Date of Patent: August 9, 2016
    Assignees: Allergan, Inc., Arch Personal Care Products, L.P.
    Inventors: James Vincent Gruber, Smitha Rao, Rahul Mehta, Sujatha Sonti
  • Patent number: 9376659
    Abstract: Disclosed is a yeast/polyphenol ferment extract, and a personal care composition including the yeast/polyphenol ferment extract. Also disclosed is a method for preparing and using the yeast/polyphenol extract and the personal care composition.
    Type: Grant
    Filed: July 23, 2009
    Date of Patent: June 28, 2016
    Assignee: ARCH PERSONAL CARE PRODUCTS, L.P.
    Inventors: Smitha Rao, James Vincent Gruber, Geoffrey Jamison Brooks
  • Publication number: 20140178315
    Abstract: The present invention relates to anhydrous or essentially anhydrous compositions intended for topical application on keratinaceous surfaces, wherein the composition includes a) an ionic fluid and b) a thickener. The compositions are advantageous for allowing the ionic fluid to act as the continuous phase of a topical formulation.
    Type: Application
    Filed: December 20, 2013
    Publication date: June 26, 2014
    Applicant: Arch Chemicals, Inc.
    Inventors: James Vincent Gruber, Vito Cataldo, Khat Kevin Lou
  • Publication number: 20140045240
    Abstract: Compositions comprising metabolized conditioned growth medium and/or metabolized cell extract and methods of use are described. The metabolized conditioned growth medium and metabolized cell extract compositions may be formulated with an acceptable carrier into injectable or topical formulations, for example, as a cream, lotion or gel, and may be used in cosmeceutical or pharmaceutical applications. The metabolized conditioned growth medium and metabolized cell extract may also be further processed to concentrate or reduce one or more factors or components contained within the metabolized conditioned growth medium or metabolized cell extract. The growth medium may be conditioned by any eukaryotic cell. The metabolized conditioned growth medium and metabolized cell extract may be used to prevent or treat a condition, for example, a skin condition.
    Type: Application
    Filed: October 7, 2013
    Publication date: February 13, 2014
    Applicant: Allergan, Inc.
    Inventors: James Vincent Gruber, Smitha Rao, Rahul Mehta, Sujatha D. Sonti
  • Publication number: 20140037675
    Abstract: Compositions comprising metabolized conditioned growth medium and/or metabolized cell extract and methods of use are described. The metabolized conditioned growth medium and metabolized cell extract compositions may be formulated with an acceptable carrier into injectable or topical formulations, for example, as a cream, lotion or gel, and may be used in cosmeceutical or pharmaceutical applications. The metabolized conditioned growth medium and metabolized cell extract may also be further processed to concentrate or reduce one or more factors or components contained within the metabolized conditioned growth medium or metabolized cell extract. The growth medium may be conditioned by any eukaryotic cell. The metabolized conditioned growth medium and metabolized cell extract may be used to prevent or treat a condition, for example, a skin condition.
    Type: Application
    Filed: October 7, 2013
    Publication date: February 6, 2014
    Applicant: Allergan, Inc.
    Inventors: James Vincent Gruber, Smitha Rao, Rahul Mehta, Sujatha D. Sonti
  • Publication number: 20140037676
    Abstract: Compositions comprising metabolized conditioned growth medium and/or metabolized cell extract and methods of use are described. The metabolized conditioned growth medium and metabolized cell extract compositions may be formulated with an acceptable carrier into injectable or topical formulations, for example, as a cream, lotion or gel, and may be used in cosmeceutical or pharmaceutical applications. The metabolized conditioned growth medium and metabolized cell extract may also be further processed to concentrate or reduce one or more factors or components contained within the metabolized conditioned growth medium or metabolized cell extract. The growth medium may be conditioned by any eukaryotic cell. The metabolized conditioned growth medium and metabolized cell extract may be used to prevent or treat a condition, for example, a skin condition.
    Type: Application
    Filed: October 7, 2013
    Publication date: February 6, 2014
    Applicant: Allergan, Inc.
    Inventors: James Vincent Gruber, Smitha Rao, Rahul Mehta, Sujatha D. Sonti
  • Publication number: 20140038256
    Abstract: Compositions comprising metabolized conditioned growth medium and/or metabolized cell extract and methods of use are described. The metabolized conditioned growth medium and metabolized cell extract compositions may be formulated with an acceptable carrier into injectable or topical formulations, for example, as a cream, lotion or gel, and may be used in cosmeceutical or pharmaceutical applications. The metabolized conditioned growth medium and metabolized cell extract may also be further processed to concentrate or reduce one or more factors or components contained within the metabolized conditioned growth medium or metabolized cell extract. The growth medium may be conditioned by any eukaryotic cell. The metabolized conditioned growth medium and metabolized cell extract may be used to prevent or treat a condition, for example, a skin condition.
    Type: Application
    Filed: October 7, 2013
    Publication date: February 6, 2014
    Applicant: Allergan, Inc.
    Inventors: James Vincent Gruber, Smitha Rao, Rahul Mehta, Sujatha D. Sonti
  • Publication number: 20140037677
    Abstract: Compositions comprising metabolized conditioned growth medium and/or metabolized cell extract and methods of use are described. The metabolized conditioned growth medium and metabolized cell extract compositions may be formulated with an acceptable carrier into injectable or topical formulations, for example, as a cream, lotion or gel, and may be used in cosmeceutical or pharmaceutical applications. The metabolized conditioned growth medium and metabolized cell extract may also be further processed to concentrate or reduce one or more factors or components contained within the metabolized conditioned growth medium or metabolized cell extract. The growth medium may be conditioned by any eukaryotic cell. The metabolized conditioned growth medium and metabolized cell extract may be used to prevent or treat a condition, for example, a skin condition.
    Type: Application
    Filed: October 7, 2013
    Publication date: February 6, 2014
    Applicant: Allergan, Inc.
    Inventors: James Vincent Gruber, Smitha Rao, Rahul Mehta, Sujatha D. Sonti