Abstract: The present invention relates to specific binding members, particularly antibodies and fragments thereof, which bind to amplified epidermal growth factor receptor (EGFR) and to the de2-7 EGFR truncation of the EGFR. In particular, the epitope recognized by the specific binding members, particularly antibodies and fragments thereof, is enhanced or evident upon aberrant post-translational modification. These specific binding members are useful in the diagnosis and treatment of cancer. The binding members of the present invention may also be used in therapy in combination with chemotherapeutics or anti-cancer agents and/or with other antibodies or fragments thereof.

Abstract: A flexible strip of material having sharp protruding crowns which, once installed on wire, rope, cable, poles, or other similar objects in which rodents are utilizing as runways, will repel such rodents by inaccessibility and therefore cause them to turn back to the point where they first contacted the wire, rope or other objects. Thus preventing such rodents from gaining access to ships, buildings, or other areas where wires, ropes or other objects are connected.