Abstract: An imaging system is provided. A first imaging system captures initial sensor data in a form of visible domain data. A second imaging system captures subsequent sensor data in a form of second domain data, wherein the initial and subsequent sensor data are of different spectral domains. A controller subsystem detects at least one region of interest in real-time by applying a machine learning technique to the visible domain data, localizes at least one object of interest in the at least one region of interest to generate positional data for the at least one object of interest, and autonomously steers a point of focus of the second imaging system to a region of a scene including the object of interest to capture the second domain data responsive to the positional data.