Abstract: Various examples described herein are directed to systems and methods of detecting damage to an analyte sensor using analyte sensor impedance values. In some examples, a method of assessing sensor membrane integrity using sensor electronics comprises determining an impedance parameter of an analyte sensor and determining a membrane integrity state of the analyte sensor based on the impedance parameter.

Abstract: Various examples are directed to systems and methods of and using analyte sensors. An example analyte sensor system comprises an analyte sensor and a hardware device in communication with the analyte sensor. The hardware device may be configured to perform operations comprising applying a first bias voltage to the analyte sensor, the first bias voltage less than an operational bias voltage of the analyte sensor, measuring a first current at the analyte sensor when the first bias voltage is applied, and applying a second bias voltage to the analyte sensor. The operations may further comprise measuring a second current at the analyte sensor when the second bias voltage is applied, detecting a plateau bias voltage using the first current and the second current, determining that the plateau bias voltage is less than a plateau bias voltage threshold, and executing a responsive action at the analyte sensor.

Abstract: Systems and methods disclosed provide ways for Health Care Professionals (HCPs) to be involved in initial patient system set up so that the data received is truly transformative, such that the patient not just understands what all the various numbers mean but also how the data can be used. For example, in one implementation, a CGM device is configured for use by a HCP, and includes a housing and a circuit configured to receive a signal from a transmitter coupled to an indwelling glucose sensor. A calibration module converts the received signal into clinical units. A user interface is provided that is configured to display a measured glucose concentration in the clinical units. The user interface is further configured to receive input data about a patient level, where the input data about the patient level causes the device to operate in a mode appropriate to the patient level.

Abstract: Systems and methods disclosed provide ways for Health Care Professionals (HCPs) to be involved in initial patient system set up so that the data received is truly transformative, such that the patient not just understands what all the various numbers mean but also how the data can be used. For example, in one implementation, a CGM device is configured for use by a HCP, and includes a housing and a circuit configured to receive a signal from a transmitter coupled to an indwelling glucose sensor. A calibration module converts the received signal into clinical units. A user interface is provided that is configured to display a measured glucose concentration in the clinical units. The user interface is further configured to receive input data about a patient level, where the input data about the patient level causes the device to operate in a mode appropriate to the patient level.

Abstract: An apparatus comprising: an input interface configured to provide signals from at least two sensors for at least two postures including: signals, dependent upon blood presence, from a first sensor when a subject is in a first posture; signals, dependent upon blood presence, from the first sensor when the subject is in a second posture; signals, dependent upon blood presence, from a second sensor when the subject is in the first posture; and signals, dependent upon blood presence. from the second sensor when the subject is in the second posture; and processing circuitry configured to determine and output a metric by combining, according to pre-defined calibration data the provided signals.

Abstract: An apparatus including an input interface configured to provide signals from at least two sensors for at least two postures including: signals, dependent upon blood presence, from a first sensor when a subject is in a first posture; signals, dependent upon blood presence, from the first sensor when the subject is in a second posture; signals, dependent upon blood presence, from a second sensor when the subject is in the first posture; and signals, dependent upon blood presence, from the second sensor when the subject is in the second posture; and processing circuitry configured to determine and output a metric by combining, according to predefined calibration data the provided signals.

Abstract: An apparatus including an input interface configured to provide signals from at least two sensors for at least two postures including: signals, dependent upon blood presence, from a first sensor when a subject is in a first posture; signals, dependent upon blood presence, from the first sensor when the subject is in a second posture; signals, dependent upon blood presence, from a second sensor when the subject is in the first posture; and signals, dependent upon blood presence. from the second sensor when the subject is in the second posture; and processing circuitry configured to determine and output a metric by combining, according to pre-defined calibration data the provided signals.

Abstract: A post-operative, arterial patency monitoring system for monitoring patency of an artery of a limb including: a first probe positioned adjacent a first tissue area of a limb for producing first output signals dependent upon a first arterial blood supply to the first tissue area; a second probe positioned adjacent a second different tissue area of the limb for producing second, different output signals dependent upon a second arterial blood supply to the second tissue area; and means for processing the first output signals to produce a first arterial blood supply metric for the first arterial blood supply and a second, different, arterial blood supply metric for the first arterial blood supply; means for processing the second output signals to produce the first arterial blood supply metric for the second arterial blood supply and the second arterial blood supply metric for the second arterial blood supply; means for using a predetermined function that takes as its arguments at least the first and second arteri

Abstract: A system for assessing blood circulation in a subject's limb, comprising: including detection means for detecting a signal dependent upon the arterial blood volume in a limb of the subject when the subject is in a first posture and also when the subject is in a second posture, different to the first posture; and processing means for calculating a quantitative indicator that is dependent upon the ratio of the signal for the first posture to the signal for the second posture.