Patents by Inventor Vincent D. Antle

Vincent D. Antle has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Manufacturing process for cyclodextrin derivatives
    Patent number: 9751957
    Abstract: A process and equipment assembly for reacting a substituent precursor with a cyclodextrin starting material to provide a raw product comprising a cyclodextrin derivative and 1% or less of an initial amount of the substituent precursor is provided. The process of the present invention provides cyclodextrin derivatives in substantially shorter time and with fewer side products than previous processes that utilize substantially the same starting materials.
    Type: Grant
    Filed: February 14, 2013
    Date of Patent: September 5, 2017
    Assignee: CyDex Pharmaceuticals, Inc.
    Inventors: Vincent D. Antle, Jose R. Matos
  • Sulfoalkyl ether cyclodextrin compositions
    Patent number: 9750822
    Abstract: SAE-CD compositions are provided, along with methods of making and using the same. The SAE-CD compositions comprise a sulfoalkyl ether cyclodextrin having an absorption of less than 0.5 A.U. due to a drug-degrading agent, as determined by UV/vis spectrophotometry at a wavelength of 245 nm to 270 nm for an aqueous solution containing 300 mg of the SAE-CD composition per mL of solution in a cell having a 1 cm path length.
    Type: Grant
    Filed: August 10, 2016
    Date of Patent: September 5, 2017
    Assignee: Cydex Pharmaceuticals, Inc.
    Inventor: Vincent D. Antle
  • ALKYLATED CYCLODEXTRIN COMPOSITIONS AND PROCESSES FOR PREPARING AND USING THE SAME
    Publication number: 20170158781
    Abstract: The present invention related to low-chloride alkylated cyclodextrin compositions, along with processes for preparing and using the same. The processes of the present invention provide alkylated cyclodextrins with low levels of drug-degrading agents and chloride.
    Type: Application
    Filed: November 14, 2016
    Publication date: June 8, 2017
    Inventors: Vincent D. Antle, Alvaro Lopes, Daniel Monteiro
  • SULFOALKYL ETHER CYCLODEXTRIN COMPOSITIONS
    Publication number: 20160346405
    Abstract: SAE-CD compositions are provided, along with methods of making and using the same. The SAE-CD compositions comprise a sulfoalkyl ether cyclodextrin having an absorption of less than 0.5 A.U. due to a drug-degrading agent, as determined by UV/vis spectrophotometry at a wavelength of 245 nm to 270 nm for an aqueous solution containing 300 mg of the SAE-CD composition per mL of solution in a cell having a 1 cm path length.
    Type: Application
    Filed: August 10, 2016
    Publication date: December 1, 2016
    Inventor: Vincent D. Antle
  • Alkylated cyclodextrin compositions and processes for preparing and using the same
    Patent number: 9493582
    Abstract: The present invention related to low-chloride alkylated cyclodextrin compositions, along with processes for preparing and using the same. The processes of the present invention provide alkylated cyclodextrins with low levels of drug-degrading agents and chloride.
    Type: Grant
    Filed: February 27, 2013
    Date of Patent: November 15, 2016
    Assignee: Cydex Pharmaceuticals, Inc.
    Inventors: Vincent D. Antle, Alvaro Lopes, Daniel Monteiro
  • SULFOALKYL ETHER CYCLODEXTRIN COMPOSITIONS
    Publication number: 20160158384
    Abstract: SAE-CD compositions are provided, along with methods of making and using the same. The SAE-CD compositions comprise a sulfoalkyl ether cyclodextrin having an absorption of less than 0.5 A.U. due to a drug-degrading agent, as determined by UV/vis spectrophotometry at a wavelength of 245 nm to 270 nm for an aqueous solution containing 300 mg of the SAE-CD composition per mL of solution in a cell having a 1 cm path length.
    Type: Application
    Filed: November 30, 2015
    Publication date: June 9, 2016
    Inventor: Vincent D. Antle
  • MANUFACTURING PROCESS FOR CYCLODEXTRIN DERIVATIVES
    Publication number: 20160009826
    Abstract: A process and equipment assembly for reacting a substituent precursor with a cyclodextrin starting material to provide a raw product comprising a cyclodextrin derivative and 1% or less of an initial amount of the substituent precursor is provided, The process of the present invention provides cyclodextrin derivatives in substantially shorter time and with fewer side products than previous processes that utilize substantially the same starting materials.
    Type: Application
    Filed: February 15, 2013
    Publication date: January 14, 2016
    Inventors: Vincent D. Antle, Jose R Matos
  • Sulfoalkyl ether cyclodextrin compositions
    Patent number: 9200088
    Abstract: SAE-CD compositions are provided, along with methods of making and using the same. The SAE-CD compositions comprise a sulfoalkyl ether cyclodextrin having an absorption of less than 0.5 A.U. due to a drug-degrading agent, as determined by UV/vis spectrophotometry at a wavelength of 245 nm to 270 nm for an aqueous solution containing 300 mg of the SAE-CD composition per mL of solution in a cell having a 1 cm path length.
    Type: Grant
    Filed: March 7, 2013
    Date of Patent: December 1, 2015
    Assignee: Cydex Pharmaceuticals, Inc.
    Inventor: Vincent D. Antle
  • ALKYLATED CYCLODEXTRIN COMPOSITIONS AND PROCESSES FOR PREPARING AND USING THE SAME
    Publication number: 20150284479
    Abstract: The present invention related to low-chloride alkylated cyclodextrin compositions, along with processes for preparing and using the same. The processes of the present invention provide alkylated cyclodextrins with low levels of drug-degrading agents and chloride.
    Type: Application
    Filed: October 21, 2013
    Publication date: October 8, 2015
    Inventors: Vincent D. Antle, Álvaro Lopes, Daniel Monteiro
  • ALKYLATED CYCLODEXTRIN COMPOSITIONS AND PROCESSES FOR PREPARING AND USING THE SAME
    Publication number: 20150045311
    Abstract: The present invention related to low-chloride alkylated cyclodextrin compositions, along with processes for preparing and using the same. The processes of the present invention provide alkylated cyclodextrins with low levels of drug-degrading agents and chloride.
    Type: Application
    Filed: February 27, 2013
    Publication date: February 12, 2015
    Inventor: Vincent D. Antle