Patents by Inventor Vincent Deubel

Vincent Deubel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Neurovirulent strain of the West Nile virus and uses thereof
    Patent number: 9657276
    Abstract: Neuroinvasive and neurovirulent strain of the West Nile virus, named IS-98-ST1, nucleic acid molecules derived from its genome, proteins and peptides encoded by said nucleic acid molecules, and uses thereof.
    Type: Grant
    Filed: March 31, 2014
    Date of Patent: May 23, 2017
    Assignees: Institut Pasteur, Kimron Veterinary Institute
    Inventors: Despres Philippe, Vincent Deubel, Jean-Louis Guenet, Marie-Therese Drouet, Mertyn Malkinson, Caroline Banet, Marie-Pascale Frenkiel, Marie-Pierre Courageot, Fasseli Coulibaly, Adeline Catteau, Marie Flamand, Patrick Weber, Pierre-Emmanuel Ceccaldi
  • Neurovirulent Strain of the West Nile Virus and Uses Thereof
    Publication number: 20140237631
    Abstract: Neuroinvasive and neurovirulent strain of the West Nile virus, named IS-98-ST1, nucleic acid molecules derived from its genome, proteins and peptides encoded by said nucleic acid molecules, and uses thereof.
    Type: Application
    Filed: March 31, 2014
    Publication date: August 21, 2014
    Applicants: KIMRON VETERINARY INSTITUTE, INSTITUT PASTEUR
    Inventors: Despres Philippe, Vincent Deubel, Jean-Louis Guenet, Marie-Therese Drouet, Mertyn Malkinson, Caroline Banet, Marie-Pascale Frenkiel, Marie-Pierre Courageot, Fasseli Coulibaly, Adeline Catteau, Marie Flamand, Patrick Weber, Pierre-Emmanuel Ceccaldi
  • Neurovirulent strain of the West Nile virus and uses thereof
    Patent number: 8715693
    Abstract: Neuroinvasive and neurovirulent strain of the West Nile virus, named IS-98-ST1, nucleic acid molecules derived from its genome, proteins and peptides encoded by said nucleic acid molecules, and uses thereof.
    Type: Grant
    Filed: March 16, 2012
    Date of Patent: May 6, 2014
    Assignees: Institut Pasteur, Kimron Veterinary Institute
    Inventors: Philippe Despres, Vincent Deubel, Jean-Louis Guenet, Marie-Thérèse Drouet, Mertyn Malkinson, Caroline Banet, Marie-Pascale Frenkiel, Marie-Pierre Courageot, Fasséli Coulibaly, Adeline Catteau, Marie Flamand, Patrick Weber, Pierre-Emmanuel Ceccaldi
  • Assay for the diagnosis of flaviviral infection using antibodies with high affinity for NS1 protein of flavivirusi in hexameric form
    Patent number: 8709427
    Abstract: The invention concerns a method for early detection of a flavivirus-induced infection, comprising the detection of the flavivirus non-structural glycoprotein NS1 in a biological sample during the clinical phase of the infection, by an immunological method using at least two identical or different antibodies, the first antibody consisting of polyclonal or monoclonal antibodies pre-selected for their high affinity for said NS1 protein hexameric in shape.
    Type: Grant
    Filed: July 26, 2011
    Date of Patent: April 29, 2014
    Assignee: Institut Pasteur
    Inventors: Marie Flamand, Françoise Megret, Sophie Alcon, Antoine Talarmin, Philippe Despres, Vincent Deubel
  • NEUROVIRULENT STRAIN OF THE WEST NILE VIRUS AND USES THEREOF
    Publication number: 20120266261
    Abstract: Neuroinvasive and neurovirulent strain of the West Nile virus, named IS-98-ST1, nucleic acid molecules derived from its genome, proteins and peptides encoded by said nucleic acid molecules, and uses thereof.
    Type: Application
    Filed: March 16, 2012
    Publication date: October 18, 2012
    Inventors: Philippe Despres, Vincent Deubel, Jean-Louis Guenet, Marie-Thérèse Drouet, Mertyn Malkinson, Caroline Banet, Marie-Pascale Frenkiel, Marie-Pierre Courageot, Fasséli Coulibaly, Adeline Catteau, Marie Flamand, Patrick Weber, Pierre-Emmanuel Ceccaldi
  • EARLY DETECTION OF FLAVIVIRUSES USING THE NS1 GLYCOPROTEIN
    Publication number: 20120009216
    Abstract: The invention concerns a method for early detection of a flavivirus-induced infection, comprising the detection of the flavivirus non-structural glycoprotein NS1 in a biological sample during the clinical phase of the infection, by an immunological method using at least two identical or different antibodies, the first antibody consisting of polyclonal or monoclonal antibodies pre-selected for their high affinity for said NS1 protein hexameric in shape.
    Type: Application
    Filed: July 26, 2011
    Publication date: January 12, 2012
    Inventors: Marie Flamand, Françoise Megret, Sophie Alcon, Antoine Talarmin, Philippe Despres, Vincent Deubel
  • NEUROVIRULENT STRAIN OF THE WEST NILE VIRUS AND USES THEREOF
    Publication number: 20100099854
    Abstract: Neuroinvasive and neurovirulent strain of the West Nile virus, named IS-98-ST1, nucleic acid molecules derived from its genome, proteins and peptides encoded by said nucleic acid molecules, and uses thereof.
    Type: Application
    Filed: April 30, 2008
    Publication date: April 22, 2010
    Applicants: INSTITUT PASTEUR, KIMRON VETERINARY INSTITUTE
    Inventors: PHILIPPE DESPRES, VINCENT DEUBEL, JEAN-LOUIS GUENET, MARIE-THERESE DROUET, MERTYN MALKINSON, CAROLINE BANET, MARIE-PASCALE FRENKIEL, MARIE-PIERRE COURAGEOT, FASSELI COULIBALY, ADELINE CATTEAU, MARIE FLAMAND, PATRICK WEBER, PIERRE-EMMANUEL CECCALDI
  • Early detection of flaviviruses using the NS1 glycoprotein
    Patent number: 7670766
    Abstract: The invention concerns a method for early detection of a flavivirus-induced infection, comprising the detection of the flavivirus non-structural glycoprotein NS1 in a biological sample during the clinical phase of the infection, by an immunological method using at least two identical or different antibodies, the first antibody consisting of polyclonal or monoclonal antibodies pre-selected for their high affinity for said NS1 protein hexameric in shape.
    Type: Grant
    Filed: September 11, 2007
    Date of Patent: March 2, 2010
    Assignee: Institut Pasteur
    Inventors: Marie Flamand, Françoise Megret, Sophie Alcon, Antoine Talarmin, Philippe Despres, Vincent Deubel
  • Early detection of flaviviruses using the NS1 glycoprotein
    Publication number: 20090226478
    Abstract: The invention concerns a method for early detection of a flavivirus-induced infection, comprising the detection of the flavivirus non-structural glycoprotein NS1 in a biological sample during the clinical phase of the infection, by an immunological method using at least two identical or different antibodies, the first antibody consisting of polyclonal or monoclonal antibodies pre-selected for their high affinity for said NS1 protein hexameric in shape.
    Type: Application
    Filed: August 21, 2007
    Publication date: September 10, 2009
    Inventors: Marie Flamand, Francoise Megret, Sophie Alcon, Antoine Talarmin, Philippe Despres, Vincent Deubel
  • Early detection of flaviviruses using the NS1 glycoprotein
    Publication number: 20090068213
    Abstract: The invention concerns a method for early detection of a flavivirus-induced infection, comprising the detection of the flavivirus non-structural glycoprotein NS1 in a biological sample during the clinical phase of the infection, by an immunological method using at least two identical or different antibodies, the first antibody consisting of polyclonal or monoclonal antibodies pre-selected for their high affinity for said NS1 protein hexameric in shape.
    Type: Application
    Filed: September 11, 2007
    Publication date: March 12, 2009
    Inventors: Marie Flamand, Francoise Megret, Sophie Alcon, Antoine Talarmin, Phillippe Despres, Vincent Deubel
  • Neurovirulent strain of the West Nile virus and uses thereof
    Patent number: 7390495
    Abstract: Neuroinvasive and neurovirulent strain of the West Nile virus, named IS-98-ST1, nucleic acid molecules derived from its genome, proteins and peptides encoded by said nucleic acid molecules, and uses thereof.
    Type: Grant
    Filed: October 4, 2004
    Date of Patent: June 24, 2008
    Assignees: Institut Pasteur, Kimron Veterinary Institute
    Inventors: Philippe Despres, Vincent Deubel, Jean-Louis Guenet, Marie-Therese Drouet, Mertyn Malkinson, Caroline Banet, Marie-Pascale Frenkiel, Marie-Pierre Courageot, Fasseli Coulibaly, Adeline Catteau, Marie Flamand, Patrick Weber, Pierre-Emmanuel Ceccaldi
  • Assay for the diagnosis of flaviviral infection using antibodies with high affinity for NS1 protein of flavivirus in hexameric form
    Patent number: 7282341
    Abstract: The invention concerns a method for early detection of a flavivirus-induced infection, comprising the detection of the flavivirus non-structural glycoprotein NS1 in a biological sample during the clinical phase of the infection, by an immumological method using at least two identical or different antibodies, the first antibody consisting of polyclonal or monoclonal antibodies pre-selected for their high affinity for said NS1 protein hexameric in shape.
    Type: Grant
    Filed: December 21, 2004
    Date of Patent: October 16, 2007
    Assignee: Institut Pasteur
    Inventors: Marie Flamand, Françoise Megret, Sophie Alcon, Antoine Talarmin, Philippe Despres, Vincent Deubel
  • Method for detecting Nipah virus and method for providing immunoprotection against Henipa viruses
    Publication number: 20070150972
    Abstract: The present invention provides an animal model for monitoring Nipah virus infection, a method for the quantitative detection and rapid characterization of Nipah virus RNA in a sample, a composition which can be used to provide immunoprotection in an individual as well as monoclonal antibodies which neutralize Nipah and Hendra virus and can be used for prophylaxis, treatment, and/or prevention.
    Type: Application
    Filed: September 8, 2006
    Publication date: June 28, 2007
    Applicant: INSTITUT PASTEUR
    Inventors: Marie-Claude George Courbot, Fabian Wild, Vincent Deubel, Robin Buckland, Hugues Contamin, Thong Wong Kum, Philippe Loth
  • Use of golden hamster as infectivity model of SARS
    Publication number: 20060143719
    Abstract: A model system for sudden acute respiratory syndrome infection (SARS) in humans, comprising a non-human animal infected with a SARS-causing coronavirus (CoV), wherein the non-human animal is a golden hamster.
    Type: Application
    Filed: August 16, 2005
    Publication date: June 29, 2006
    Inventors: Philippe Marianneau, Vincent Deubel, Hugues Contamin, Ingrid Marendat, Philippe Loth, Marie Georges-Courbot
  • Method for detecting Nipah virus and method for providing immunoprotection against Henipa viruses
    Publication number: 20060053501
    Abstract: The present invention provides an animal model for monitoring Nipah virus infection, a method for the quantitative detection and rapid characterization of Nipah virus RNA in a sample, a composition which can be used to provide immunoprotection in an individual as well as monoclonal antibodies which neutralize Nipah and Hendra virus and can be used for prophylaxis, treatment, and/or prevention.
    Type: Application
    Filed: May 18, 2005
    Publication date: March 9, 2006
    Applicant: INSTITUT PASTEUR
    Inventors: Marie-Claude George Courbot, Fabian Wild, Vincent Deubel, Robin Buckland, Hugues Contamin, Thong Kum, Philippe Loth
  • Assay for the diagnosis of flaviviral infection using antibodies with high affinity for NS1 protein of flavivirus in hexameric form
    Publication number: 20050186562
    Abstract: The invention concerns a method for early detection of a flavivirus-induced infection, comprising the detection of the flavivirus non-structural glycoprotein NS1 in a biological sample during the clinical phase of the infection, by an immumological method using at least two identical or different antibodies, the first antibody consisting of polyclonal or monoclonal antibodies pre-selected for their high affinity for said NS1 protein hexameric in shape.
    Type: Application
    Filed: December 21, 2004
    Publication date: August 25, 2005
    Inventors: Marie Flamand, Francoise Megret, Sophie Alcon, Antoine Talarmin, Philippe Despres, Vincent Deubel
  • Neurovirulent strain of the west nile virus and uses thereof
    Publication number: 20050164170
    Abstract: Neuroinvasive and neurovirulent strain of the West Nile virus, named IS-98-ST1, nucleic acid molecules derived from its genome, proteins and peptides encoded by said nucleic acid molecules, and uses thereof.
    Type: Application
    Filed: October 4, 2004
    Publication date: July 28, 2005
    Applicants: INSTITUT PASTEUR, KIMRON VETERINARY INSTITUTE
    Inventors: Philippe Despres, Vincent Deubel, Jean-Louis Guenet, Marie-Therese Drouet, Mertyn Malkinson, Caroline Banet, Marie-Pascale Frenkiel, Marie-Pierre Courageot, Fasseli Coulibaly, Adeline Catteau, Marie Flamand, Patrick Weber, Pierre-Emmanuel Ceccaldi
  • Assay for the diagnosis of flaviviral infection using antibodies with high affinity for NS1 protein of flavivirus in hexameric form
    Patent number: 6870032
    Abstract: The invention concerns a method for early detection of a flavivirus-induced infection, comprising the detection of the flavivirus non-structural glycoprotein NS1 in a biological sample during the clinical phase of the infection, by an immunological method using at least two identical or different antibodies, the first antibody consisting of polyclonal or monoclonal antibodies pre-selected for their high affinity for said NS1 protein hexameric in shape.
    Type: Grant
    Filed: June 9, 2000
    Date of Patent: March 22, 2005
    Assignee: Institut Pasteur
    Inventors: Marie Flamand, Françoise Megret, Sophie Alcon, Antoine Talarmin, Philippe Despres, Vincent Deubel
  • Pro-apoptoic fragments of the dengue virus envelope glycoproteins
    Publication number: 20040101862
    Abstract: The present invention relates to pro-apoptotic fragments of the Dengue virus pRM and E glycoproteins, methods of screening for molecules capable of inducing apoptosis and methods of inducing apoptosis in a cell.
    Type: Application
    Filed: May 19, 2003
    Publication date: May 27, 2004
    Inventors: Philippe Despres, Marie-Pierre Courageot, Vincent Deubel, Adeline Catteau
  • Pro-apoptotic fragments of the dengue virus envelope glycoproteins
    Publication number: 20040049016
    Abstract: The present invention relates to pro-apoptotic fragments of the Dengue virus pRM and E glycoproteins, methods of screening for molecules capable of inducing apoptosis and methods of inducing apoptosis in a cell.
    Type: Application
    Filed: August 6, 2003
    Publication date: March 11, 2004
    Applicant: INSTITUT PASTEUR
    Inventors: Philippe Despres, Marie-Pierre Courageot, Vincent Deubel, Adeline Catteau