Patents by Inventor Vincent DiNapoli

Vincent DiNapoli has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Non-invasive detection of spreading depolarization using scalp electroencephalography
    Patent number: 10849518
    Abstract: Non-invasive electroencephalogram (EEG)-based methods for detecting a spreading depolarization secondary to a brain injury in a patient who exhibits high-amplitude delta activity in at least one channel of a scalp EEG of an injured brain hemisphere of the patient include (a) recording a baseline scalp EEG pattern in the patient at a channel exhibiting high amplitude delta activity; (b) recording a continuous scalp EEG pattern in the patient across a time frame at the at least one channel; and (c) detecting a spreading depolarization during the time frame by observing at least one feature indicative of a spreading depolarization in the continuous scalp EEG recording pattern relative to the baseline scalp EEG pattern at the at least one channel. Scalp EEG recordings are time-compressed prior to analysis. Methods of treating brain-injured patients and triaging brain-injured patients apply the non-invasive EEG methods.
    Type: Grant
    Filed: June 30, 2015
    Date of Patent: December 1, 2020
    Assignee: University of Cincinnati
    Inventors: Jed A. Hartings, J. Adam Wilson, Jason M. Hinzman, Norberto Andaluz, Vincent DiNapoli, Sebastian Pollandt
  • Non-Invasive Detection of Spreading Depolarization Using Scalp Electroencephalography
    Publication number: 20170135594
    Abstract: Non-invasive electroencephalogram (EEG)-based methods for detecting a spreading depolarization secondary to a brain injury in a patient who exhibits high-amplitude delta activity in at least one channel of a scalp EEG of an injured brain hemisphere of the patient include (a) recording a baseline scalp EEG pattern in the patient at a channel exhibiting high amplitude delta activity; (b) recording a continuous scalp EEG pattern in the patient across a time frame at the at least one channel; and (c) detecting a spreading depolarization during the time frame by observing at least one feature indicative of a spreading depolarization in the continuous scalp EEG recording pattern relative to the baseline scalp EEG pattern at the at least one channel. Scalp EEG recordings are time-compressed prior to analysis. Methods of treating brain-injured patients and triaging brain-injured patients apply the non-invasive EEG methods.
    Type: Application
    Filed: June 30, 2015
    Publication date: May 18, 2017
    Inventors: Jed A. Hartings, J. Adam Wilson, Jason M. Hinzman, Norberto Andaluz, Vincent DiNapoli, Sebastian Pollandt