Patents by Inventor Vincent Freeman

Vincent Freeman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210055314
    Abstract: Provided herein are antigenic molecules that can be used to generate antibodies capable of binding to a vitamin D derivative, such as 25-hydroxyvitamin D2 and/or 25-hydroxyvitamin D3, or a 25-hydroxyvitamin D analog, such as a vitamin D-C22 immunogenic molecule or compound. Antibodies produced using these antigenic molecules, and related antigenic compounds, are also described. In addition, disclosed herein are methods for detecting vitamin D deficiency in a subject, methods for treating a subject suspected of having a vitamin D deficiency, methods for monitoring progression of vitamin D deficiency in a subject, and methods for monitoring treatment of vitamin D deficiency in a subject in need thereof. The methods involve the detection or quantification of 25-hydroxyvitamin D2 and D3.
    Type: Application
    Filed: November 3, 2020
    Publication date: February 25, 2021
    Applicant: Siemens Healthcare Diagnostics Inc.
    Inventors: Niver Panosian Sahakian, Bruce A. Campbell, Spencer Hsiang-Hsi Lin, James Vincent Freeman, Qimu Liao, Ramon A. Evangelista
  • Patent number: 10837973
    Abstract: Provided herein are antigenic molecules that can be used to generate antibodies capable of binding to a vitamin D derivative, such as 25-hydroxyvitamin D2 and/or 25-hydroxyvitamin D3, or a 25-hydroxyvitamin D analog, such as a vitamin D-C22 immunogenic molecule or compound. Antibodies produced using these antigenic molecules, and related antigenic compounds, are also described. In addition, disclosed herein are methods for detecting vitamin D deficiency in a subject, methods for treating a subject suspected of having a vitamin D deficiency, methods for monitoring progression of vitamin D deficiency in a subject, and methods for monitoring treatment of vitamin D deficiency in a subject in need thereof. The methods involve the detection or quantification of 25-hydroxyvitamin D2 and D3.
    Type: Grant
    Filed: March 7, 2018
    Date of Patent: November 17, 2020
    Assignee: Siemens Healthcare Diagnostics Inc.
    Inventors: Niver Panosian Sahakian, Bruce A. Campbell, Spencer Hsiang-Hsi Lin, James Vincent Freeman, Qimu Liao, Ramon A. Evangelista
  • Publication number: 20180372761
    Abstract: Provided herein are antigenic molecules that can be used to generate antibodies capable of binding to a vitamin D derivative, such as 25-hydroxyvitamin D2 and/or 25-hydroxyvitamin D3, or a 25-hydroxyvitamin D analog, such as a vitamin D-C22 immunogenic molecule or compound. Antibodies produced using these antigenic molecules, and related antigenic compounds, are also described. In addition, disclosed herein are methods for detecting vitamin D deficiency in a subject, methods for treating a subject suspected of having a vitamin D deficiency, methods for monitoring progression of vitamin D deficiency in a subject, and methods for monitoring treatment of vitamin D deficiency in a subject in need thereof. The methods involve the detection or quantification of 25-hydroxyvitamin D2 and D3.
    Type: Application
    Filed: March 7, 2018
    Publication date: December 27, 2018
    Applicant: Siemens Healthcare Diagnostics Inc.
    Inventors: NIVER PANOSIAN SAHAKIAN, BRUCE A. CAMPBELL, SPENCER HSIANG-HSI LIN, JAMES VINCENT FREEMAN, QIMU LIAO, RAMON A. EVANGELISTA
  • Publication number: 20140336156
    Abstract: Provided herein are antigenic molecules that can be used to generate antibodies capable of binding to a vitamin D derivative, such as 25-hydroxyvitamin D2 and/or 25-hydroxyvitamin D3, or a 25-hydroxyvitamin D analog, such as a vitamin D-C22 immunogenic molecule or compound. Antibodies produced using these antigenic molecules, and related antigenic compounds, are also described. In addition, disclosed herein are methods for detecting vitamin D deficiency in a subject, methods for treating a subject suspected of having a vitamin D deficiency, methods for monitoring progression of vitamin D deficiency in a subject, and methods for monitoring treatment of vitamin D deficiency in a subject in need thereof. The methods involve the detection or quantification of 25-hydroxyvitamin D2 and D3.
    Type: Application
    Filed: July 18, 2014
    Publication date: November 13, 2014
    Inventors: NIVER PANOSIAN SAHAKIAN, Bruce A. Campbell, Spencer Hsiang-Hsi Lin, JAMES Vincent FREEMAN, Qimu Liao, RAMON A. EVANGELISTA
  • Patent number: 8785603
    Abstract: Provided herein are antigenic molecules that can be used to generate antibodies capable of binding to a vitamin D derivative, such as 25-hydroxyvitamin D2 and/or 25-hydroxyvitamin D3, or a 25-hydroxyvitamin D analog, such as a vitamin D-C22 immunogenic molecule or compound. Antibodies produced using these antigenic molecules, and related antigenic compounds, are also described. In addition, disclosed herein are methods for detecting vitamin D deficiency in a subject, methods for treating a subject suspected of having a vitamin D deficiency, methods for monitoring progression of vitamin D deficiency in a subject, and methods for monitoring treatment of vitamin D deficiency in a subject in need thereof. Also provided are methods and reagents for the detection or quantification of 25-hydroxyvitamin D2 and D3, methods for stabilizing vitamin D analogs, and methods for separating 25-hydroxyvitamin D2 and D3 from vitamin D binding protein in a biological sample.
    Type: Grant
    Filed: April 27, 2012
    Date of Patent: July 22, 2014
    Assignee: Siemens Healthcare Diagnostics Inc.
    Inventors: Niver Panosian Sahakian, Bruce A. Campbell, Spencer Hsiang-Hsi Lin, James Vincent Freeman, Qimu Liao, Ramon A. Evangelista
  • Publication number: 20130059825
    Abstract: Provided herein are antigenic molecules that can be used to generate antibodies capable of binding to a vitamin D derivative, such as 25-hydroxyvitamin D2 and/or 25-hydroxyvitamin D3, or a 25-hydroxyvitamin D analog, such as a vitamin D-C22 immunogenic molecule or compound. Antibodies produced using these antigenic molecules, and related antigenic compounds, are also described. In addition, disclosed herein are methods for detecting vitamin D deficiency in a subject, methods for treating a subject suspected of having a vitamin D deficiency, methods for monitoring progression of vitamin D deficiency in a subject, and methods for monitoring treatment of vitamin D deficiency in a subject in need thereof. Also provided are methods and reagents for the detection or quantification of 25-hydroxyvitamin D2 and D3, methods for stabilizing vitamin D analogs, and methods for separating 25-hydroxyvitamin D2 and D3 from vitamin D binding protein in a biological sample.
    Type: Application
    Filed: April 27, 2012
    Publication date: March 7, 2013
    Applicant: Siemens Healthcare Diagnostics Inc.
    Inventors: Niver Panosian Sahakian, Bruce A. Campbell, Spencer Hsiang-Hsi Lin, James Vincent Freeman, Qimu Liao, Ramon A. Evangelista
  • Patent number: 7954895
    Abstract: The present invention provides a child seat (1) comprising a seat back (3), a headrest (4) which is moveable relative to the seat back (3), and a removable harness which may be installed for use in securing an occupant to the seat (1), wherein the headrest (4) is coupled to the seat back (3) such that the headrest (4) may undergo a first extent of movement relative to the seat back (3) when the harness is installed and may only undergo a second further extent of movement relative to the seat back (3) when the harness is removed. In this regard, only when the harness is removed from an operative position, namely one where it is installed such that it can be used to restrain a child, can the headrest (4) undergo its second further extent of movement relative to the seat back (3). This ensures that the headrest (4) is not inappropriately positioned for the group of child being restrained thereby.
    Type: Grant
    Filed: June 30, 2006
    Date of Patent: June 7, 2011
    Assignee: Britax Excelsior Limited
    Inventors: Vincent Freeman, Iain Powell, Gareth James
  • Publication number: 20090236881
    Abstract: The present invention concerns an article holder for a child seat, the holder comprising a holder portion (6) for holding one or more articles, and a mounting (7) in relation to which said holder portion is movably mounted. The holder portion and said mounting are configured for relative sliding movement there-between along an arcuate path.
    Type: Application
    Filed: June 30, 2006
    Publication date: September 24, 2009
    Applicant: BRITAX EXCELSIOR LIMITED
    Inventors: Vincent Freeman, Iain Powell, James Gareth
  • Publication number: 20090212613
    Abstract: The present invention provides a child seat (1) comprising a seat back (3), a headrest (4) which is moveable relative to the seat back (3), and a removable harness which may be installed for use in securing an occupant to the seat (1), wherein the headrest (4) is coupled to the seat back (3) such that the headrest (4) may undergo a first extent of movement relative to the seat back (3) when the harness is installed and may only undergo a second further extent of movement relative to the seat back (3) when the harness is removed. In this regard, only when the harness is removed from an operative position, namely one where it is installed such that it can be used to restrain a child, can the headrest (4) undergo its second further extent of movement relative to the seat back (3). This ensures that the headrest (4) is not inappropriately positioned for the group of child being restrained thereby.
    Type: Application
    Filed: June 30, 2006
    Publication date: August 27, 2009
    Applicant: BRITAX EXCELSIOR LIMITED
    Inventors: Vincent Freeman, Iain Powell, Gareth James
  • Publication number: 20080090220
    Abstract: A multimedia reproduction system comprises a computing subsystem operably connected to and controlling one or more of video, audio, and olfactory subsystems. The system accepts user input and adapts a multimedia presentation in response thereto. The subsystems are easily separable and configured in carrying cases that protect them during transport. The subsystems easily connect (physically and electronically) to each other upon delivery to form a system that presents 3-D, high definition video, surround-sound audio, and even scents from local and/or remote sources.
    Type: Application
    Filed: August 28, 2007
    Publication date: April 17, 2008
    Inventors: Vincent Freeman, Greg Wilson