Patents by Inventor Vincent Freeman
Vincent Freeman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Publication number: 20240094227Abstract: Provided herein are antigenic molecules that can be used to generate antibodies capable of binding to a vitamin D derivative, such as 25-hydroxyvitamin D2 and/or 25-hydroxyvitamin D3, or a 25-hydroxyvitamin D analog, such as a vitamin D-C22 immunogenic molecule or compound. Antibodies produced using these antigenic molecules, and related antigenic compounds, are also described. In addition, disclosed herein are methods for detecting vitamin D deficiency in a subject, methods for treating a subject suspected of having a vitamin D deficiency, methods for monitoring progression of vitamin D deficiency in a subject, and methods for monitoring treatment of vitamin D deficiency in a subject in need thereof. The methods involve the detection or quantification of 25-hydroxyvitamin D2 and D3.Type: ApplicationFiled: October 12, 2023Publication date: March 21, 2024Applicant: Siemens Healthcare Diagnostics Inc.Inventors: Niver Panosian Sahakian, Bruce A. Campbell, Spencer Hsiang-Hsi Lin, James Vincent Freeman, Qimu Liao, Ramon A. Evangelista
-
Patent number: 11815517Abstract: Provided herein are antigenic molecules that can be used to generate antibodies capable of binding to a vitamin D derivative, such as 25-hydroxyvitamin D2 and/or 25-hydroxyvitamin D3, or a 25-hydroxyvitamin D analog, such as a vitamin D-C22 immunogenic molecule or compound. Antibodies produced using these antigenic molecules, and related antigenic compounds, are also described. In addition, disclosed herein are methods for detecting vitamin D deficiency in a subject, methods for treating a subject suspected of having a vitamin D deficiency, methods for monitoring progression of vitamin D deficiency in a subject, and methods for monitoring treatment of vitamin D deficiency in a subject in need thereof. The methods involve the detection or quantification of 25-hydroxyvitamin D2 and D3.Type: GrantFiled: November 3, 2020Date of Patent: November 14, 2023Assignee: Siemens Healthcare Diagnostics Inc.Inventors: Niver Panosian Sahakian, Bruce A. Campbell, Spencer Hsiang-Hsi Lin, James Vincent Freeman, Qimu Liao, Ramon A. Evangelista
-
Publication number: 20210055314Abstract: Provided herein are antigenic molecules that can be used to generate antibodies capable of binding to a vitamin D derivative, such as 25-hydroxyvitamin D2 and/or 25-hydroxyvitamin D3, or a 25-hydroxyvitamin D analog, such as a vitamin D-C22 immunogenic molecule or compound. Antibodies produced using these antigenic molecules, and related antigenic compounds, are also described. In addition, disclosed herein are methods for detecting vitamin D deficiency in a subject, methods for treating a subject suspected of having a vitamin D deficiency, methods for monitoring progression of vitamin D deficiency in a subject, and methods for monitoring treatment of vitamin D deficiency in a subject in need thereof. The methods involve the detection or quantification of 25-hydroxyvitamin D2 and D3.Type: ApplicationFiled: November 3, 2020Publication date: February 25, 2021Applicant: Siemens Healthcare Diagnostics Inc.Inventors: Niver Panosian Sahakian, Bruce A. Campbell, Spencer Hsiang-Hsi Lin, James Vincent Freeman, Qimu Liao, Ramon A. Evangelista
-
Patent number: 10837973Abstract: Provided herein are antigenic molecules that can be used to generate antibodies capable of binding to a vitamin D derivative, such as 25-hydroxyvitamin D2 and/or 25-hydroxyvitamin D3, or a 25-hydroxyvitamin D analog, such as a vitamin D-C22 immunogenic molecule or compound. Antibodies produced using these antigenic molecules, and related antigenic compounds, are also described. In addition, disclosed herein are methods for detecting vitamin D deficiency in a subject, methods for treating a subject suspected of having a vitamin D deficiency, methods for monitoring progression of vitamin D deficiency in a subject, and methods for monitoring treatment of vitamin D deficiency in a subject in need thereof. The methods involve the detection or quantification of 25-hydroxyvitamin D2 and D3.Type: GrantFiled: March 7, 2018Date of Patent: November 17, 2020Assignee: Siemens Healthcare Diagnostics Inc.Inventors: Niver Panosian Sahakian, Bruce A. Campbell, Spencer Hsiang-Hsi Lin, James Vincent Freeman, Qimu Liao, Ramon A. Evangelista
-
Publication number: 20180372761Abstract: Provided herein are antigenic molecules that can be used to generate antibodies capable of binding to a vitamin D derivative, such as 25-hydroxyvitamin D2 and/or 25-hydroxyvitamin D3, or a 25-hydroxyvitamin D analog, such as a vitamin D-C22 immunogenic molecule or compound. Antibodies produced using these antigenic molecules, and related antigenic compounds, are also described. In addition, disclosed herein are methods for detecting vitamin D deficiency in a subject, methods for treating a subject suspected of having a vitamin D deficiency, methods for monitoring progression of vitamin D deficiency in a subject, and methods for monitoring treatment of vitamin D deficiency in a subject in need thereof. The methods involve the detection or quantification of 25-hydroxyvitamin D2 and D3.Type: ApplicationFiled: March 7, 2018Publication date: December 27, 2018Applicant: Siemens Healthcare Diagnostics Inc.Inventors: NIVER PANOSIAN SAHAKIAN, BRUCE A. CAMPBELL, SPENCER HSIANG-HSI LIN, JAMES VINCENT FREEMAN, QIMU LIAO, RAMON A. EVANGELISTA
-
Publication number: 20140336156Abstract: Provided herein are antigenic molecules that can be used to generate antibodies capable of binding to a vitamin D derivative, such as 25-hydroxyvitamin D2 and/or 25-hydroxyvitamin D3, or a 25-hydroxyvitamin D analog, such as a vitamin D-C22 immunogenic molecule or compound. Antibodies produced using these antigenic molecules, and related antigenic compounds, are also described. In addition, disclosed herein are methods for detecting vitamin D deficiency in a subject, methods for treating a subject suspected of having a vitamin D deficiency, methods for monitoring progression of vitamin D deficiency in a subject, and methods for monitoring treatment of vitamin D deficiency in a subject in need thereof. The methods involve the detection or quantification of 25-hydroxyvitamin D2 and D3.Type: ApplicationFiled: July 18, 2014Publication date: November 13, 2014Inventors: NIVER PANOSIAN SAHAKIAN, Bruce A. Campbell, Spencer Hsiang-Hsi Lin, JAMES Vincent FREEMAN, Qimu Liao, RAMON A. EVANGELISTA
-
Patent number: 8785603Abstract: Provided herein are antigenic molecules that can be used to generate antibodies capable of binding to a vitamin D derivative, such as 25-hydroxyvitamin D2 and/or 25-hydroxyvitamin D3, or a 25-hydroxyvitamin D analog, such as a vitamin D-C22 immunogenic molecule or compound. Antibodies produced using these antigenic molecules, and related antigenic compounds, are also described. In addition, disclosed herein are methods for detecting vitamin D deficiency in a subject, methods for treating a subject suspected of having a vitamin D deficiency, methods for monitoring progression of vitamin D deficiency in a subject, and methods for monitoring treatment of vitamin D deficiency in a subject in need thereof. Also provided are methods and reagents for the detection or quantification of 25-hydroxyvitamin D2 and D3, methods for stabilizing vitamin D analogs, and methods for separating 25-hydroxyvitamin D2 and D3 from vitamin D binding protein in a biological sample.Type: GrantFiled: April 27, 2012Date of Patent: July 22, 2014Assignee: Siemens Healthcare Diagnostics Inc.Inventors: Niver Panosian Sahakian, Bruce A. Campbell, Spencer Hsiang-Hsi Lin, James Vincent Freeman, Qimu Liao, Ramon A. Evangelista
-
Publication number: 20130059825Abstract: Provided herein are antigenic molecules that can be used to generate antibodies capable of binding to a vitamin D derivative, such as 25-hydroxyvitamin D2 and/or 25-hydroxyvitamin D3, or a 25-hydroxyvitamin D analog, such as a vitamin D-C22 immunogenic molecule or compound. Antibodies produced using these antigenic molecules, and related antigenic compounds, are also described. In addition, disclosed herein are methods for detecting vitamin D deficiency in a subject, methods for treating a subject suspected of having a vitamin D deficiency, methods for monitoring progression of vitamin D deficiency in a subject, and methods for monitoring treatment of vitamin D deficiency in a subject in need thereof. Also provided are methods and reagents for the detection or quantification of 25-hydroxyvitamin D2 and D3, methods for stabilizing vitamin D analogs, and methods for separating 25-hydroxyvitamin D2 and D3 from vitamin D binding protein in a biological sample.Type: ApplicationFiled: April 27, 2012Publication date: March 7, 2013Applicant: Siemens Healthcare Diagnostics Inc.Inventors: Niver Panosian Sahakian, Bruce A. Campbell, Spencer Hsiang-Hsi Lin, James Vincent Freeman, Qimu Liao, Ramon A. Evangelista
-
Patent number: 7954895Abstract: The present invention provides a child seat (1) comprising a seat back (3), a headrest (4) which is moveable relative to the seat back (3), and a removable harness which may be installed for use in securing an occupant to the seat (1), wherein the headrest (4) is coupled to the seat back (3) such that the headrest (4) may undergo a first extent of movement relative to the seat back (3) when the harness is installed and may only undergo a second further extent of movement relative to the seat back (3) when the harness is removed. In this regard, only when the harness is removed from an operative position, namely one where it is installed such that it can be used to restrain a child, can the headrest (4) undergo its second further extent of movement relative to the seat back (3). This ensures that the headrest (4) is not inappropriately positioned for the group of child being restrained thereby.Type: GrantFiled: June 30, 2006Date of Patent: June 7, 2011Assignee: Britax Excelsior LimitedInventors: Vincent Freeman, Iain Powell, Gareth James
-
Publication number: 20090236881Abstract: The present invention concerns an article holder for a child seat, the holder comprising a holder portion (6) for holding one or more articles, and a mounting (7) in relation to which said holder portion is movably mounted. The holder portion and said mounting are configured for relative sliding movement there-between along an arcuate path.Type: ApplicationFiled: June 30, 2006Publication date: September 24, 2009Applicant: BRITAX EXCELSIOR LIMITEDInventors: Vincent Freeman, Iain Powell, James Gareth
-
Publication number: 20090212613Abstract: The present invention provides a child seat (1) comprising a seat back (3), a headrest (4) which is moveable relative to the seat back (3), and a removable harness which may be installed for use in securing an occupant to the seat (1), wherein the headrest (4) is coupled to the seat back (3) such that the headrest (4) may undergo a first extent of movement relative to the seat back (3) when the harness is installed and may only undergo a second further extent of movement relative to the seat back (3) when the harness is removed. In this regard, only when the harness is removed from an operative position, namely one where it is installed such that it can be used to restrain a child, can the headrest (4) undergo its second further extent of movement relative to the seat back (3). This ensures that the headrest (4) is not inappropriately positioned for the group of child being restrained thereby.Type: ApplicationFiled: June 30, 2006Publication date: August 27, 2009Applicant: BRITAX EXCELSIOR LIMITEDInventors: Vincent Freeman, Iain Powell, Gareth James
-
Publication number: 20080090220Abstract: A multimedia reproduction system comprises a computing subsystem operably connected to and controlling one or more of video, audio, and olfactory subsystems. The system accepts user input and adapts a multimedia presentation in response thereto. The subsystems are easily separable and configured in carrying cases that protect them during transport. The subsystems easily connect (physically and electronically) to each other upon delivery to form a system that presents 3-D, high definition video, surround-sound audio, and even scents from local and/or remote sources.Type: ApplicationFiled: August 28, 2007Publication date: April 17, 2008Inventors: Vincent Freeman, Greg Wilson