Abstract: A method for determining a probe signal for acoustically interrogating an electrochemical system, the method including transmitting a first signal, called the calibration signal, including a wave train of multiple frequencies, the spectral density associated with each frequency being identical; receiving the response of the electrochemical system to the calibration signal; determining, on the basis of the received response and for each frequency of the calibration signal, a signal attenuation factor; determining, for each attenuation factor, a correction factor according to the attenuation factor so as to associate a correction factor with each frequency of the calibration signal; and determining the probe signal, the probe signal being obtained by multiplying the spectral density associated with each frequency of the calibration signal by the correction factor corresponding to the frequency in question.

Abstract: The disclosure relates to methods and systems for biological assays and assay transport systems.

Abstract: The invention relates to methods for phenotypic antimicrobial susceptibility profiling of unidentified pathogens directly from patient samples and uses thereof, including providing timely important information for evidence-based management of patients with infections from unidentified pathogens.

Abstract: Described herein are microfluidic diagnostic methods and devices using electrokinetic modules for the isolation of targets (e.g., cells, bacteria, biomolecules) from biological samples, PCR amplification of DNA isolated from the targets, and real-time quantification of the amplified DNA using impedance sensing. Sample preparation, PCR amplification, and impedance sensing are thus performed using a single integrated platform.