Abstract: This application relates to stem cell compositions and methods for restoring age-related tissue loss in the face and other selected areas of the body. In a first embodiment, a composition includes stem cells and hyaluronic acid as a carrier wherein the stem cells are peripheral blood stem cells, bone marrow-derived blood stem cells, or mesenchymal stem cells.

Abstract: A method of determining genetic predisposition for deficiency in a specific health function of a person using single nucleotide polymorphism (SNP) analysis is provided. The method includes performing a SNP genotyping assay of three or more genes using a sample obtained from the person, obtaining a SNP panel which includes predetermined identifier SNPs, comparing the SNP panel with a predetermined criterion defining the genetic predisposition for deficiency in a specific health function; and reporting presence of genetic predisposition for deficiency in this health function if the SNP panel meets the predetermined criterion. The health function includes glycation, inflammation, DNA methylation, oxidation or DNA repair.

Abstract: A supplement composition for enhancement of methylation process is provided, which contains vitamin B6 (as pyridoxine HCl), folic acid, vitamin B12 (as cyanocobalamin), betaine HCl, and methylsulfonylmethane; and also contains S-adenosylmethionine. The supplement composition further includes silymarin (from milk thistle seed extract), N-acetyl L-cysteine, and cruciferious blend which includes broccoli (brassica oleracea var. talica), kale (brassica oleracea var. acephala), and radish (raphanus sativus). Further provided is a method of using the supplement composition for enhancement of methylation process.

Abstract: A supplement composition for enhancement of anti-inflammation process is provided, which contains nettle leaf extract, hops extract, and turmeric rhizome extract. The supplement composition further includes hyaluronic acid, sodium salt, glucosamine sulfate, and chondroitin sulfate. Further provided is a method of using the supplement composition for enhancement of anti-inflammation process.

Abstract: An antioxidant supplement composition is provided, which contains vitamin E, resveratrol, and alpha-lipoic acid. The supplement composition can further contain N-acetyl-L-cysteine. Further provided is a method of using the antioxidant supplement composition for enhancing an individual's resistance to oxidative damages. The method includes administering the antioxidant supplement composition daily in a dosage contains from 50 to 200 IU of vitamin E, from 5 to 40 mg of resveratrol, from 50 to 400 mg of alpha-lipoic acid. In a higher strength treatment, the daily dosage further includes from 150 to 600 mg of N-acetyl-L-cysteine.

Abstract: A supplement composition for enhancing DNA repair process is provided, which contains a carotenoid compound, a nicotinamide compound, a zinc compound, D-ribose, and a water soluble extract of an Uncaria species. The composition can further contain resveratrol and a glucosinolate compound. Further provided is a method of using the supplement composition for enhancing an individual's DNA repair process.

Abstract: A dietary supplement composition for enhancement of the insulin sensitivity is provided, which includes thiamin, chromium, alpha-lipoic acid, L-carnosine, and vanadium. The supplement composition further includes cinnamon bark and banana leaf extract (corosolic acid) for an extra strength formula. Alternatively, the supplement composition includes a herbal blend which includes boswellic acid, gymnema sylvestre leaf extract, and bitter melon extract. Further provided is a method of using the supplement composition for enhancing an individual's insulin sensitivity.

Abstract: A treatment method for restoring of age related tissue loss in the face or selected areas of the body is disclosed which includes injecting an injectable composition containing a growth factor and hyaluronic acid as a carrier into the dermis, the hypodermis, or both, in various areas of the face, or selected areas of the body of a person to stimulate collagen, elastin, or fat cell production, thereby restoring age related tissue loss in the face and selected areas of the body. Further disclosed is an injectable composition for restoring of age related tissue loss in the face and selected areas of the body, which contains a growth factor and hyaluronic acid as a carrier for providing time release of the growth factor into tissues. The growth factor can be insulin, insulin-like growth factor, thyroid hormone, fibroblast growth factor, estrogen, retinoic acid, or their combinations.

Abstract: A supplement for administering to a human, or other mammals, includes a carotenoid material, a nicotinamide material, a zinc source material, and a water soluble extract material of an Uncaria species. The supplement can be in a form for oral administration, particularly in a form of nutritional drink, or in a formulation for parenteral administration. Also disclosed is a method of treating a human including administering to an individual the supplement daily in amounts effective, in combination, to improve the individual's resistance to DNA damage, enhance DNA repair capacity, stimulate immune cell function, and inhibit tumor cell growth.

Abstract: A topical composition includes a water soluble extract of an Uncaria species in a concentration range from about 0.1% to 15%, and a dermatologically acceptable medium suitable for topical application. The topical composition can further contain deuterium reduced water which has a deuterium concentration in a range from 0.1 ppm to about 110 ppm. Also disclosed are methods using the topical composition for improving skin cell's resistance to DNA damage and/or enhancing skin cell's DNA repair capacity; for protecting the skin from damage, and/or treating skin damage, caused by exposure to ultraviolet light; for treating and/or preventing skin wrinkles, keratosis and lipofuscin deposit.

Abstract: A treatment system for administering to a human or other animals and the method of use for improving resistance to DNA damage, enhancing DNA repair capacity and stimulating immune function are provided. The treatment system includes a carotenoid material; a nicotinamide material, a zinc source material, a water soluble extract material of an Uncaria species and a deuterium-reduced aqueous fluid containing 0.1 to 110 ppm deuterium.

Abstract: Methods of re-profiling adult stem cells are disclosed, which include recording electromagnetic signals from an embryonic stem cell, cytoplasm thereof, individual components of the cytoplasm, nucleus thereof, or chromosome from the nucleus, using an electronic device and storing the electromagnetic signals; and then transmitting the electromagnetic signals to the adult stem cell of a mammal the same species in vitro, and transferring transmitted adult stem cell back into the mammal. Alternatively, the recorded electromagnetic signals are transmitted to the adult stem cells in vivo. The methods also include reactivating silenced genes in the mammal prior to transmitting the electromagnetic signals to the adult stem cell of the mammal. Transmission of electromagnetic signals from embryonic stem cells to adult stem cells provides molecular information of embryonic environment, which induces aged adult stem cells functioning as young cells.