Abstract: The connecting device includes a mounting portion configured to be mounted on a vial; a female coupling end piece intended to be coupled to the male coupling end piece of a container; a perforation element configured to perforate a perforable closure element equipping the vial; a protective cap which is removable and which at least partially delimits an inner chamber in which the female coupling end piece extends; at least one passage orifice opening into the inner chamber and intended for the passage of a sterilization gas; and a closing membrane located upstream of the at least one passage orifice relative to a direction of circulation of the sterilization gas through the connecting device, the closing membrane being porous and permeable to the sterilization gas.

Abstract: This medical device (2) comprises a pre-filled syringe (3) comprising a syringe body (4) and a piston (16) mounted sliding in the syringe body (4), the syringe body (4) and the piston (16) delimiting an internal chamber (17) containing a fluid to be administered; and a package (21) in which the pre-filled syringe (3) is arranged, the package (21) comprising first and second package portions (22, 23) mounted movable relative to each other between a storage configuration in which the first and second package portions (22, 23) prevent the pre-filled syringe (4) from being removed from the package (21), and an open configuration in which the first and second package portions (22, 23) allow the pre-filled syringe (3) to be removed from the package (21), a movement of the first and second package portions (22, 23) from the storage configuration to the open configuration causing the piston (16) to move from a first piston position to a second piston position.

Abstract: The administration system includes an administration device including a connection tip including a tubular connecting portion; and a protective device comprising a protective portion which is detachably connected to the administration device, a closing portion closing the free end of the tubular connecting portion, and a coupling portion rotatably coupled to the protective portion and to the closing portion. The protective device delimits an inner chamber within which the connection tip extends at least partially, and further includes at least one passage orifice opening into the inner chamber, and a closure membrane covering at least partially the at least one passage orifice.

Abstract: This medical device (2) comprises a pre-filled syringe (3) comprising a syringe body (4) and a piston (16) mounted sliding in the syringe body (4), the syringe body (4) and the piston (16) delimiting an internal chamber (17) containing a fluid to be administered; and a package (21) in which the pre-filled syringe (3) is arranged, the package (21) comprising first and second package portions (22, 23) mounted movable relative to each other between a storage configuration in which the first and second package portions (22, 23) prevent the pre-filled syringe (4) from being removed from the package (21), and an open configuration in which the first and second package portions (22, 23) allow the pre-filled syringe (3) to be removed from the package (21), a movement of the first and second package portions (22, 23) from the storage configuration to the open configuration causing the piston (16) to move from a first piston position to a second piston position.

Abstract: A device to simulate a surface bleeding is provided. The device includes A source of a blood liquid; A pump system connected to the source of blood liquid and configured to provide a controlled flow of said blood liquid; A wound simulator having an open chamber connected to the pump system to receive the controlled flow of blood liquid, wherein the wound simulator includes a set of interchangeable plates having a plurality of holes arranged through said plates according to a specific pattern, and each plate being adapted to be removably mounted on the wound simulator to close the open chamber, so that blood liquid flows out of the chamber through the holes of the plate mounted on the wound simulator.

Abstract: The invention relates to a device to simulate a surface bleeding, comprising: —A source of a blood liquid, in particular a synthetic blood liquid or a blood liquid having been removed from a human body; A pump system connected to the source of blood liquid and configured to provide a controlled flow of said blood liquid; A wound simulator having an open chamber connected to the pump system to receive the controlled flow of blood liquid, wherein the wound simulator comprises a set of interchangeable plates, each plate having a plurality of holes arranged through said plate according to a specific pattern, wherein the specific pattern is different for each plate of the set of interchangeable plates, and. each plate being adapted to be removably mounted on the wound simulator to close the open chamber, so that blood liquid flows out of the chamber through the holes of the plate mounted on the wound simulator. The invention also relates to methods of use of such simulating device.

Abstract: The invention relates to a device to simulate a surface bleeding, comprising: A source of a blood liquid, in particular a synthetic blood liquid or a blood liquid having been removed from a human body; A pump system connected to the source of blood liquid and configured to provide a controlled flow of said blood liquid; A wound simulator having an open chamber connected to the pump system to receive the controlled flow of blood liquid, wherein the wound simulator comprises a set of interchangeable plates, each plate having a plurality of holes arranged through said plate according to a specific pattern, wherein the specific pattern is different for each plate of the set of interchangeable plates, and each plate being adapted to be removably mounted on the wound simulator to close the open chamber, so that blood liquid flows out of the chamber through the holes of the plate mounted on the wound simulator.

Abstract: The invention relates to collagen tubes, characterized in that they include a wall formed by a succession of continuous, cylindrical and coaxial collagen films. The invention also relates to tubules, bundles of tubules and combinations of tubes, tubules and bundles. These tubes are designed to be used in surgery, particularly in order to promote nerve regeneration.

Abstract: In a process for continuously casting a metal strand by casting metal into a straight, vertically oriented mold and subsequently drawing off the strand formed in the mold, the straight strand at first is bent into a circular arc shape in a bending zone along a transition curve, is guided along a circular arc guide and finally is straightened in a final straightening zone along a transition curve and, after this, is extracted via an approximately horizontal straight guide.