Patents by Inventor Vincent Henricus Johnnes Van der Velden

Vincent Henricus Johnnes Van der Velden has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD, REAGENTS, AND KITS FOR DETECTING MINIMAL RESIDUAL DISEASE
    Publication number: 20150160226
    Abstract: The invention relates to the field of minimal residual disease (MRD) diagnostics, which is progressively more applied for the evaluation of treatment effectiveness in patients with a hematological malignancy, such as B-cell precursor acute lymphoblastic leukemia (BCP-ALL), B-cell chronic lymphocytic leukemia (B-CLL), and multiple myeloma (MM). Provided are unique reagent compositions with carefully selected and thoroughly tested combinations of antibodies, for ?8-color flow cytometric stainings as well as for 10-color and 12-color flow cytometric stainings, which can reach sensitivities of at least 10?4, even down to 10?5. Also provided are diagnostic kits and methods for detecting MRD.
    Type: Application
    Filed: June 14, 2013
    Publication date: June 11, 2015
    Inventors: Jacobus Johannes Maria van Dongen, Jose Alberto Orfao de Matos Correia e Vale, Juan Alejandro Flores Montero, Julia Maria Almeida Parra, Vincent Henricus Johnnes Van der Velden, Sebastian Bottcher, Anthonie Willem Langerak, Ester Mejstrikova, Tomasz Szczepanski, Matthias Ritgen, Paulo Jorge Monteiro Da Silva Lucio