Patents by Inventor Vincent Hsieh
Vincent Hsieh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11892402Abstract: An apparatus for the high throughput measurement of optical properties of liquid samples placed into the wells of a multiwell plate is disclosed. An optical fiber within a fiber bundle containing no corrective optics between the fiber ends and the well plate bottom illuminates the sample in order to induce fluorescence, and multiple fibers collect emission radiation and transmit it to a fluorescence detector such as a spectrometer. Other embodiments involve a light scattering illumination source with detection fibers located in either the same bundle containing the fluorescence monitoring fibers or an independent light scattering detection bundle for the measurement of static and/or dynamic light scattering. Some embodiments of the invention permit the measurement of phase analysis light scattering. Thus the measurement of multiple optical properties of a liquid sample may be made simultaneously or in succession. A method for these measurements is also disclosed.Type: GrantFiled: March 9, 2021Date of Patent: February 6, 2024Assignee: Wyatt Technology, LLCInventors: Vincent Hsieh, Mario Yasa, Jr., Steven C. Minne
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Publication number: 20240027349Abstract: A method comprises: directing, using an objective and a first reflective surface, first autofocus light toward a sensor, the first autofocus light reflected from a first surface of a substrate; preventing second autofocus light from reaching the sensor, the second autofocus light reflected from a second surface of the substrate; and directing, using the objective and a second reflective surface, emission light toward the sensor, the emission light originating from a sample at the substrate.Type: ApplicationFiled: October 4, 2023Publication date: January 25, 2024Inventors: Simon Prince, Danilo Condello, Vincent Hsieh, Krysada Phounsiri, John O’Shaughnessy
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Patent number: 11815458Abstract: A method comprises: directing, using an objective and a first reflective surface, first autofocus light toward a sensor, the first autofocus light reflected from a first surface of a substrate; preventing second autofocus light from reaching the sensor, the second autofocus light reflected from a second surface of the substrate; and directing, using the objective and a second reflective surface, emission light toward the sensor, the emission light originating from a sample at the substrate.Type: GrantFiled: December 22, 2020Date of Patent: November 14, 2023Assignee: Illumina, Inc.Inventors: Simon Prince, Danilo Condello, Vincent Hsieh, Krysada Phounsiri, John O'Shaughnessy
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Publication number: 20230143682Abstract: Apparatus and methods for controlling heating of an objective in a linescanning sequencing system to improve resolution are disclosed. In accordance with a first implementation, an apparatus includes or comprises a beam source for providing input radiation and a beam shaping group including or comprising one or more optical elements positioned to receive the input radiation from the beam source, and to perform beam shaping on the input radiation to form a shaped beam. The apparatus further including or comprising an objective positioned to receive the shaped beam and to transform the shaped beam into a probe beam and configured to provide the probe beam to a focal plane of the objective for optically probing a sample. The beam shaping group is configured to adjust one or more properties of the shaped beam over time to generally uniformly heat the objective over a region of incidence for the shaped beam.Type: ApplicationFiled: November 4, 2022Publication date: May 11, 2023Inventors: Danilo Condello, Dakota Watson, Andrew Carson, Vincent Hsieh, Steven Boege, Changqin Ding, Stanley Hong
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Publication number: 20230068952Abstract: The present disclosure describes a flow cell, a read head, and a skid attachment for measuring real-time molecular weight for downstream process control. In an embodiment, the flow cell comprises a hollow cylindrical tube, an inlet flange connected to an inlet of the tube, and an outlet flange connected to an outlet of the tube. In an embodiment, the read head comprises at least one push rod, at least two line contacts, where the at least one push rod is configured to push an outer side wall of a flow cell against the at least two line contacts. In an embodiment, the skid attachment comprises a plurality of arms connected to an enclosure configured to house at least a multi-angle light scattering instrument comprising a read head.Type: ApplicationFiled: November 8, 2022Publication date: March 2, 2023Applicant: Wyatt Technology CorporationInventors: Drew Amaral, Vincent Hsieh
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Patent number: 11493441Abstract: The present disclosure describes a flow cell, a read head, and a skid attachment for measuring real-time molecular weight for downstream process control. In an embodiment, the flow cell comprises a hollow cylindrical tube, an inlet flange connected to an inlet of the tube, and an outlet flange connected to an outlet of the tube. In an embodiment, the read head comprises at least one push rod, at least two line contacts, where the at least one push rod is configured to push an outer side wall of a flow cell against the at least two line contacts. In an embodiment, the skid attachment comprises a plurality of arms connected to an enclosure configured to house at least a multi-angle light scattering instrument comprising a read head.Type: GrantFiled: January 15, 2020Date of Patent: November 8, 2022Assignee: WYATT TECHNOLOGY CORPORATIONInventors: Drew Amaral, Vincent Hsieh
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Publication number: 20210215608Abstract: An apparatus for the high throughput measurement of optical properties of liquid samples placed into the wells of a multiwell plate is disclosed. An optical fiber within a fiber bundle containing no corrective optics between the fiber ends and the well plate bottom illuminates the sample in order to induce fluorescence, and multiple fibers collect emission radiation and transmit it to a fluorescence detector such as a spectrometer. Other embodiments involve a light scattering illumination source with detection fibers located in either the same bundle containing the fluorescence monitoring fibers or an independent light scattering detection bundle for the measurement of static and/or dynamic light scattering. Some embodiments of the invention permit the measurement of phase analysis light scattering. Thus the measurement of multiple optical properties of a liquid sample may be made simultaneously or in succession. A method for these measurements is also disclosed.Type: ApplicationFiled: March 9, 2021Publication date: July 15, 2021Applicant: Wyatt Technology CorporationInventors: Vincent Hsieh, Mario Yasa, Steven C. Minne
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Publication number: 20210199587Abstract: A method comprises: directing, using an objective and a first reflective surface, first autofocus light toward a sensor, the first autofocus light reflected from a first surface of a substrate; preventing second autofocus light from reaching the sensor, the second autofocus light reflected from a second surface of the substrate; and directing, using the objective and a second reflective surface, emission light toward the sensor, the emission light originating from a sample at the substrate.Type: ApplicationFiled: December 22, 2020Publication date: July 1, 2021Inventors: Simon Prince, Danilo Condello, Vincent Hsieh, Krysada Phounsiri, John O'Shaughnessy
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Patent number: 10942120Abstract: An apparatus for the high throughput measurement of optical properties of liquid samples placed into the wells of a multiwell plate is disclosed. An optical fiber within a fiber bundle containing no corrective optics between the fiber ends and the well plate bottom illuminates the sample in order to induce fluorescence, and multiple fibers collect emission radiation and transmit it to a fluorescence detector such as a spectrometer. Other embodiments involve a light scattering illumination source with detection fibers located in either the same bundle containing the fluorescence monitoring fibers or an independent light scattering detection bundle for the measurement of static and/or dynamic light scattering. Some embodiments of the invention permit the measurement of phase analysis light scattering. Thus the measurement of multiple optical properties of a liquid sample may be made simultaneously or in succession. A method for these measurements is also disclosed.Type: GrantFiled: November 12, 2019Date of Patent: March 9, 2021Assignee: WYATT TECHNOLOGY CORPORATIONInventors: Vincent Hsieh, Mario Yasa, Jr., Steven C. Minne
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Publication number: 20200225155Abstract: The present disclosure describes a flow cell, a read head, and a skid attachment for measuring real-time molecular weight for downstream process control. In an embodiment, the flow cell comprises a hollow cylindrical tube, an inlet flange connected to an inlet of the tube, and an outlet flange connected to an outlet of the tube. In an embodiment, the read head comprises at least one push rod, at least two line contacts, where the at least one push rod is configured to push an outer side wall of a flow cell against the at least two line contacts. In an embodiment, the skid attachment comprises a plurality of arms connected to an enclosure configured to house at least a multi-angle light scattering instrument comprising a read head.Type: ApplicationFiled: January 15, 2020Publication date: July 16, 2020Applicant: Wyatt Technology CorporationInventors: Drew Amaral, Vincent Hsieh
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Publication number: 20200080939Abstract: An apparatus for the high throughput measurement of optical properties of liquid samples placed into the wells of a multiwell plate is disclosed. An optical fiber within a fiber bundle containing no corrective optics between the fiber ends and the well plate bottom illuminates the sample in order to induce fluorescence, and multiple fibers collect emission radiation and transmit it to a fluorescence detector such as a spectrometer. Other embodiments involve a light scattering illumination source with detection fibers located in either the same bundle containing the fluorescence monitoring fibers or an independent light scattering detection bundle for the measurement of static and/or dynamic light scattering. Some embodiments of the invention permit the measurement of phase analysis light scattering. Thus the measurement of multiple optical properties of a liquid sample may be made simultaneously or in succession. A method for these measurements is also disclosed.Type: ApplicationFiled: November 12, 2019Publication date: March 12, 2020Applicant: Wyatt Technology CorporationInventors: Vincent Hsieh, Mario Yasa, Steven C. Minne
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Patent number: 10473591Abstract: An apparatus for the high throughput measurement of optical properties of liquid samples placed into the wells of a multiwell plate is disclosed. An optical fiber within a fiber bundle containing no corrective optics between the fiber ends and the well plate bottom illuminates the sample in order to induce fluorescence, and multiple fibers collect emission radiation and transmit it to a fluorescence detector such as a spectrometer. Other embodiments involve a light scattering illumination source with detection fibers located in either the same bundle containing the fluorescence monitoring fibers or an independent light scattering detection bundle for the measurement of static and/or dynamic light scattering. Some embodiments of the invention permit the measurement of phase analysis light scattering. Thus the measurement of multiple optical properties of a liquid sample may be made simultaneously or in succession. A method for these measurements is also disclosed.Type: GrantFiled: May 1, 2017Date of Patent: November 12, 2019Assignee: WYATT TECHNOLOGY CORPORATIONInventors: Vincent Hsieh, Mario Yasa, Jr., Steven C Minne
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Publication number: 20180313758Abstract: An apparatus for the high throughput measurement of optical properties of liquid samples placed into the wells of a multiwell plate is disclosed. An optical fiber within a fiber bundle containing no corrective optics between the fiber ends and the well plate bottom illuminates the sample in order to induce fluorescence, and multiple fibers collect emission radiation and transmit it to a fluorescence detector such as a spectrometer. Other embodiments involve a light scattering illumination source with detection fibers located in either the same bundle containing the fluorescence monitoring fibers or an independent light scattering detection bundle for the measurement of static and/or dynamic light scattering. Some embodiments of the invention permit the measurement of phase analysis light scattering. Thus the measurement of multiple optical properties of a liquid sample may be made simultaneously or in succession. A method for these measurements is also disclosed.Type: ApplicationFiled: May 1, 2017Publication date: November 1, 2018Inventors: Vincent Hsieh, Mario Yasa, Jr., Steven C Minne
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Patent number: 9725105Abstract: Shopping container safes and related methods for securing objects are disclosed. According to an aspect, a shopping container includes a load carrier and a safe being attached to the load carrier. The safe may include a door and a lock. The lock may be configured to receive security information from an object. The lock may also determine whether to validate the received security information. Further, the lock may either fasten or unfasten the door of the safe in response to determining to validate the received security information.Type: GrantFiled: December 26, 2014Date of Patent: August 8, 2017Assignee: Toshiba Global Commerce Solutions Holdings CorporationInventors: Shun-Te Yu, Leo Lee, Merrick Wang, Vincent Hsieh
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Publication number: 20160185375Abstract: Shopping container safes and related methods for securing objects are disclosed. According to an aspect, a shopping container includes a load carrier and a safe being attached to the load carrier. The safe may include a door and a lock. The lock may be configured to receive security information from an object. The lock may also determine whether to validate the received security information. Further, the lock may either fasten or unfasten the door of the safe in response to determining to validate the received security information.Type: ApplicationFiled: December 26, 2014Publication date: June 30, 2016Inventors: Shun-Te Yu, Leo Lee, Merrick Wang, Vincent Hsieh
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Publication number: 20050086533Abstract: A method for providing secure communication in a computer network is disclosed, A method and a computer program product for secure communication, referred to as the secure proxy protocol, where, two or more clients communicate securely via a communication server.Type: ApplicationFiled: February 20, 2004Publication date: April 21, 2005Inventor: Vincent Hsieh
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Patent number: 6791720Abstract: A portable scanning apparatus comprising a scanner and a feeder. The scanner is connected to a host by a USB line through which the power of the scanner is provided. The scanner includes an application specific integrated circuit (ASIC) and an image sensing module for controlling the scanning apparatus. The image sensing module is used for receiving image signals from the document which are further outputted to the ASIC. The scanner can be selectively combined with a feeder as a sheet-fed scanner or detached from the feeder as a hand-held one. The feeder includes a motor for controlling the rolling wheel of the feeder and battery for supplying the power of the feeder.Type: GrantFiled: July 28, 2000Date of Patent: September 14, 2004Assignee: Lite-on Technology CorporationInventor: Vincent Hsieh
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Patent number: 5925126Abstract: A security shield implementation method comprising computer software for use with a computer system's software which is transparent to the user of the computer system software and utilizes the steps of system call interception and interactive command interception to control access by a user of the computer system software. The system call interception for non-interactive commands, file access, programs, networks, and the interactive commands, such as access to interactive programs, are routed and examined by redirector software. Security rule checks and log event functions are then conducted on the non-interactive commands, file access requests, programs, networks, and the interactive commands. If a non-interactive command, file access request, program, network, or an interactive command is approved, the command request is then forwarded to the computer operating system.Type: GrantFiled: March 18, 1997Date of Patent: July 20, 1999Assignee: Memco Software, Ltd.Inventor: Vincent Hsieh