Patents by Inventor Vincent J. Andaloro

Vincent J. Andaloro has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • N-methyl-D-aspartate (NMDA) receptor blockers for the prevention of atherosclerosis
    Patent number: 6469027
    Abstract: The present invention relates to the novel finding that homocysteine affects the initiation and/or progress of atherosclerosis via a receptor-mediated growth factor effect on vascular smooth muscle cells. This growth factor effect can be inhibited by N-methyl-D-aspartate antagonists via a unique receptor that is in the NMDA receptor family. Through the use of cloning and other procedures, this homocysteine receptor can be characterized in order to develop novel pharmacologic strategies that the address the receptor for the prevention and treatment of atherosclerosis.
    Type: Grant
    Filed: December 29, 1999
    Date of Patent: October 22, 2002
    Assignee: The Board of Regents of the University of Nebraska
    Inventors: Thomas H. Rosenquist, Daniel T. Monaghan, Preston F. Gadson, Vincent J. Andaloro
  • N-methyl-D-aspartate (NMDA) receptor blockers for the prevention of atherosclerosis
    Patent number: 6025369
    Abstract: The present invention relates to the novel finding that homocysteine affects the initiation and/or progress of atherosclerosis via a receptor-mediated growth factor effect on vascular smooth muscle cells. This growth factor effect can be inhibited by N-methyl-D-aspartate antagonists via a unique receptor that is in the NMDA receptor family. Through the use of cloning and other procedures, this homocysteine receptor can be characterized in order to develop novel pharmacologic strategies that the address the receptor for the prevention and treatment of atherosclerosis.
    Type: Grant
    Filed: May 2, 1997
    Date of Patent: February 15, 2000
    Assignee: The Board of Regents of the University Nebraska
    Inventors: Thomas H. Rosenquist, Daniel T. Monaghan, Preston F. Gadson, Vincent J. Andaloro