Patents by Inventor Vincent K. Tuohy

Vincent K. Tuohy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BREAST CANCER VACCINE
    Publication number: 20240075115
    Abstract: Compositions and methods for immunization against human breast cancer are disclosed. A breast cancer vaccine comprises an immunogenic polypeptide comprising human ?-lactalbumin.
    Type: Application
    Filed: December 9, 2022
    Publication date: March 7, 2024
    Inventors: Vincent K. Tuohy, Justin M. Johnson, Ritika Jaini
  • VACCINE ADJUVANTS AND FORMULATIONS
    Publication number: 20240041997
    Abstract: Compositions comprising an antigen, a carbohydrate, and a metabolizable oil, methods of administering such compositions to a subject, methods of making such compounds, and related compositions, methods, and uses.
    Type: Application
    Filed: June 27, 2023
    Publication date: February 8, 2024
    Inventors: Vincent K. Tuohy, Justin M. Johnson
  • OVARIAN CANCER VACCINES
    Publication number: 20240041798
    Abstract: Provided herein are methods, kits and compositions for the treatment and/or prevention of ovarian cancer through the induction of an immune response against Anti-Mullerian Hormone Receptor, Type II (AMHR2).
    Type: Application
    Filed: September 7, 2023
    Publication date: February 8, 2024
    Inventors: Vincent K. Tuohy, Suparna Mazumder, Justin M. Johnson
  • Ovarian cancer vaccines
    Patent number: 11786489
    Abstract: Provided herein are methods, kits and compositions for the treatment and/or prevention of ovarian cancer through the induction of an immune response against Anti-Mullerian Hormone Receptor, Type II (AMHR2).
    Type: Grant
    Filed: August 17, 2021
    Date of Patent: October 17, 2023
    Assignee: The Cleveland Clinic Foundation
    Inventors: Vincent K. Tuohy, Suparna Mazumder, Justin M. Johnson
  • AMHR2-ED CANCER VACCINE FORMULATIONS
    Publication number: 20230256068
    Abstract: Provided herein are compositions, systems, kits, and methods of using a composition comprising at least a portion of an Anti-Mullerian Hormone Receptor Type II extracellular domain (AMHR-ED), and an adjuvant comprising: i) squalene oil, ii) a non-ionic surfactant (e.g., Tween 80), iii) an emulsifier (e.g., sorbitan trioleate), and iv) a buffer (e.g., citrate buffer). In certain embodiments, such compositions are administered to a female subject to treat or prevent ovarian or endometrial cancer (e.g., by inducing expression of anti-AMHR2-ED IgG antibodies by the subject in vivo).
    Type: Application
    Filed: February 15, 2023
    Publication date: August 17, 2023
    Inventors: Vincent K. Tuohy, Suparna Mazumder, Justin M. Johnson
  • Vaccine adjuvants and formulations
    Patent number: 11684658
    Abstract: Compositions comprising an antigen, a carbohydrate, and a metabolizable oil, methods of administering such compositions to a subject, methods of making such compounds, and related compositions, methods, and uses.
    Type: Grant
    Filed: February 13, 2020
    Date of Patent: June 27, 2023
    Assignee: CLEVELAND CLINIC FOUNDATION
    Inventors: Vincent K. Tuohy, Justin M. Johnson
  • ANTI-MULLERIAN HORMONE RECEPTOR 2 ANTIBODIES AND METHODS OF USE
    Publication number: 20230078601
    Abstract: Provided herein are anti-Anti-Miillerian Hormone Receptor 2 (AMHR2) antibodies and methods of using such antibodies, for example, in the treatment of cancer.
    Type: Application
    Filed: January 29, 2021
    Publication date: March 16, 2023
    Inventors: Vincent K. Tuohy, Suparna Mazumder, Justin M. Johnson
  • Breast cancer vaccine
    Patent number: 11547749
    Abstract: Compositions and methods for immunization against human breast cancer are disclosed. A breast cancer vaccine comprises an immunogenic polypeptide comprising human ?-lactalbumin.
    Type: Grant
    Filed: September 26, 2019
    Date of Patent: January 10, 2023
    Assignee: The Cleveland Clinic Foundation
    Inventors: Vincent K. Tuohy, Justin M. Johnson, Ritika Jaini
  • VACCINE ADJUVANTS AND FORMULATIONS
    Publication number: 20210386839
    Abstract: Compositions comprising an antigen, a carbohydrate, and a metabolizable oil, methods of administering such compositions to a subject, methods of making such compounds, and related compositions, methods, and uses.
    Type: Application
    Filed: February 13, 2020
    Publication date: December 16, 2021
    Inventors: Vincent K. Tuohy, Justin M. Johnson
  • OVARIAN CANCER VACCINES
    Publication number: 20210379171
    Abstract: Provided herein are methods, kits and compositions for the treatment and/or prevention of ovarian cancer through the induction of an immune response against Anti-Mullerian Hormone Receptor, Type II (AMHR2).
    Type: Application
    Filed: August 17, 2021
    Publication date: December 9, 2021
    Inventors: Vincent K. Tuohy, Suparna Mazumder, Justin M. Johnson
  • Ovarian cancer vaccines
    Patent number: 11090284
    Abstract: Provided herein are methods, kits and compositions for the treatment and/or prevention of ovarian cancer through the induction of an immune response against Anti-Mullerian Hormone Receptor, Type II (AMHR2).
    Type: Grant
    Filed: September 2, 2016
    Date of Patent: August 17, 2021
    Assignee: The Cleveland Clinic Foundation
    Inventors: Vincent K. Tuohy, Suparna Mazumder, Justin M. Johnson
  • Breast cancer vaccine
    Patent number: 10463724
    Abstract: Compositions and methods for immunization against human breast cancer are disclosed. A breast cancer vaccine comprises an immunogenic polypeptide comprising human ?-lactalbumin.
    Type: Grant
    Filed: September 11, 2015
    Date of Patent: November 5, 2019
    Assignee: The Cleveland Clinic Foundation
    Inventors: Vincent K. Tuohy, Justin M. Johnson, Ritika Jaini
  • OVARIAN CANCER VACCINES
    Publication number: 20190134173
    Abstract: Provided herein are methods, kits and compositions for the treatment and/or prevention of ovarian cancer through the induction of an immune response against Anti-Mullerian Hormone Receptor, Type II (AMHR2).
    Type: Application
    Filed: September 2, 2016
    Publication date: May 9, 2019
    Inventors: Vincent K. Tuohy, Suparna Mazumder, Justin M. Johnson
  • Multivalent breast cancer vaccine
    Patent number: 9884098
    Abstract: Compositions and methods for immunization against human breast cancer are disclosed. In one embodiment the multivalent antigenic composition is provided comprising immunogenic polypeptides selected from the group consisting of human ?-lactalbumin, ?S1 casein, ?-casein and ?-casein.
    Type: Grant
    Filed: May 2, 2016
    Date of Patent: February 6, 2018
    Assignee: The Cleveland Clinic Foundation
    Inventor: Vincent K. Tuohy
  • Multivalent Breast Cancer Vaccine
    Publication number: 20160317635
    Abstract: Compositions and methods for immunization against human breast cancer are disclosed. In one embodiment the multivalent antigenic composition is provided comprising immunogenic polypeptides selected from the group consisting of human ?-lactalbumin, ?S1 casein, ?-casein and ?-casein.
    Type: Application
    Filed: May 2, 2016
    Publication date: November 3, 2016
    Inventor: Vincent K. Tuohy
  • Method of inducing a proinflammatory immune response to human ?-lactalbumin
    Patent number: 9446104
    Abstract: Compositions and methods for immunization against human breast cancer are disclosed. A breast cancer vaccine comprises an immunogenic polypeptide comprising human ?-lactalbumin.
    Type: Grant
    Filed: December 18, 2013
    Date of Patent: September 20, 2016
    Assignee: The Cleveland Clinic Foundation
    Inventors: Vincent K. Tuohy, Justin M. Johnson, Ritika Jaini
  • Multivalent breast cancer vaccine
    Patent number: 9327026
    Abstract: Compositions and methods for immunization against human breast cancer are disclosed. In one embodiment the multivalent antigenic composition is provided comprising immunogenic polypeptides selected from the group consisting of human ?-lactalbumin, ?S1 casein, ?-casein and ?-casein.
    Type: Grant
    Filed: April 15, 2013
    Date of Patent: May 3, 2016
    Inventor: Vincent K. Tuohy
  • Breast Cancer Vaccine
    Publication number: 20160101169
    Abstract: Compositions and methods for immunization against human breast cancer are disclosed. A breast cancer vaccine comprises an immunogenic polypeptide comprising human ?-lactalbumin.
    Type: Application
    Filed: September 11, 2015
    Publication date: April 14, 2016
    Inventors: Vincent K. Tuohy, Justin M. Johnson, Ritika Jaini
  • Alpha lactalbumin immunization methods
    Patent number: 9125848
    Abstract: Compositions and methods for immunization against human breast cancer are disclosed. A breast cancer vaccine comprises an immunogenic polypeptide comprising human ?-lactalbumin.
    Type: Grant
    Filed: June 10, 2011
    Date of Patent: September 8, 2015
    Assignee: The Cleveland Clinic Foundation
    Inventors: Vincent K. Tuohy, Justin M. Johnson, Ritika Jaini
  • DIAGNOSTIC ASSAY FOR DETECTING AND MONITORING AGE RELATED AND NOISE INDUCED HEARING LOSS
    Publication number: 20090075306
    Abstract: A method of detecting age related and/or noise induced hearing loss in a subject includes detecting in a biological sample from the subject the presence of cochlin antibodies; and correlating the level of detected cochlin antibodies to the presence or absence of age related and/or noise induced hearing loss in the subject.
    Type: Application
    Filed: May 7, 2008
    Publication date: March 19, 2009
    Inventors: Vincent K. Tuohy, Gordon B. Hughes