Patents by Inventor Vincent Lannoy

Vincent Lannoy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Organic compounds
    Patent number: 10203327
    Abstract: The present invention relates to modulators of the interaction between G-protein coupled receptor 15(GPR15) and c10orf99. The modulator may be a small chemical molecule, antibody or other therapeutic protein. Methods of medical treatment and methods of identifying modulators are also described.
    Type: Grant
    Filed: October 23, 2014
    Date of Patent: February 12, 2019
    Assignees: Novartis AG, Odega S.A.
    Inventors: Frederic Bassilana, Birgit Uta Baumgarten, Nathalie Marie-Therese Carte, Michel Detheux, Rocco Falchetto, Sebastien Hannedouche, Vincent Lannoy, Keith Mansfield, Klaus Peter Seuwen, Thomas Laurent Henri Suply
  • Ligand for G-protein coupled receptor GPR43 and uses thereof
    Publication number: 20080286806
    Abstract: The present invention is related to the G-protein coupled orphan receptor GPR43 and the identification of short chain fatty acids as natural ligands of the receptor. The invention further relates to assays for the identification of agents that modulate GPR43 ligand binding and signalling activity, as well as compositions consisting essentially of an isolated GPR43 polypeptide and an isolated short chain fatty acid. The invention also relates to diagnostic methods and kits that take advantage of the novel interaction of GPR43 with short chain fatty acids.
    Type: Application
    Filed: November 20, 2007
    Publication date: November 20, 2008
    Inventors: Emmanuel LePoul, Michel Detheux, Stephane Brezillon, Vincent Lannoy, Marc Parmentier
  • Natural ligand for orphan G protein coupled receptor GPR86 and methods of use
    Patent number: 7422846
    Abstract: The present invention is related to a method of detecting the dysregulation of GPR86 activity.
    Type: Grant
    Filed: August 31, 2005
    Date of Patent: September 9, 2008
    Assignee: Euroscreen S.A
    Inventors: Didier Communi, Nathalie Suarez, Michel Detheux, Stephane Brezillian, Vincent Lannoy, Marc Parmentier, Jean-Marie Boeynaems
  • Ligand for G-protein coupled receptor GPR43 and uses thereof
    Patent number: 7303889
    Abstract: The present invention is related to the G-protein coupled orphan receptor GPR43 and the identification of short chain fatty acids as natural ligands of the receptor. The invention further relates to assays for the identification of agents that modulate GPR43 ligand binding and signaling activity, as well as compositions consisting essentially of an isolated GPR43 polypeptide and an isolated short chain fatty acid. The invention also relates to diagnostic methods and kits that take advantage of the novel interaction of GPR43 with short chain fatty acids.
    Type: Grant
    Filed: January 7, 2003
    Date of Patent: December 4, 2007
    Assignee: Euroscreen S.A.
    Inventors: Emmanuel Le Poul, Michel Detheux, Stéphane Brézillon, Vincent Lannoy, Marc Parmentier
  • Natural ligand for orphan G protein coupled receptor GPR86 and methods of use
    Publication number: 20060078918
    Abstract: The present invention is related to a method of detecting the dysregulation of GPR86 activity.
    Type: Application
    Filed: August 31, 2005
    Publication date: April 13, 2006
    Inventors: Didier Communi, Nathalie Suarez, Michel Detheux, Stephane Brezillon, Vincent Lannoy, Marc Parmentier, Jean-Marie Boeynaems
  • Methods of identifying a ligand, an agonist, and an antagonist of G protein coupled receptor GPR86 (P2Y13)
    Patent number: 6946244
    Abstract: The present invention is related to a recombinant cell expressing a nucleotide sequence encoding a G protein coupled receptor having an amino acid sequence which presents more than 70% sequence identity with SEQ ID.NO.1 as well as to a drug screening method and kit using the orphan G protein coupled receptor GPR86, identified hereafter as receptor for ADP (P2Y13) and a homologous sequence, the corresponding polynucleotide and said recombinant cell to identify agonist, inverse agonist and antagonist compounds applicable to a diagnostic, prevention and/or treatment of various diseases and disorders.
    Type: Grant
    Filed: August 7, 2001
    Date of Patent: September 20, 2005
    Assignee: Euroscreen, S.A.
    Inventors: Didier Communi, Nathalie Suarez, Michel Detheux, Stephane Brezillion, Vincent Lannoy, Marc Parmentier, Jean-Marie Boeynaems
  • Natural ligand of orphan G protein coupled receptor GPR86 and methods of use
    Publication number: 20040005629
    Abstract: The present invention is related to a recombinant cell expressing a nucleotide sequence encoding a G protein coupled receptor having an amino acid sequence which presents more than 70% sequence identity with SEQ ID.NO. 1 as well as to a drug screening method and kit using the orphan G protein coupled receptor GPR86, identified hereafter as receptor for ADP (P2Y13) and a homologous sequence, the corresponding polynucleotide and said recombinant cell to identify agonist, inverse agonist and antagonist compounds applicable to a diagnostic, prevention and/or treatment of various diseases and disorders.
    Type: Application
    Filed: December 3, 2002
    Publication date: January 8, 2004
    Inventors: Didier Communi, Nathalie Suarez, Michel Detheux, Stephane Brezillon, Vincent Lannoy, Marc Parmentier, Jean-Marie Boeynaems
  • Ligands for G protein coupled receptor GPR7 and GPR8 and uses thereof
    Publication number: 20030232756
    Abstract: The present invention is related to the identification of a family of polypeptide ligands that bind both the GPR7 and GPR8 G-protein coupled receptors, and to their use in screening methods for the identification of modulators of GPR7/8 receptor function and for diagnostic and therapeutic applications. The invention further relates to kits which use these orphan G protein coupled receptors and their ligands to identify agonist and antagonist compounds applicable to the diagnosis, prevention and/or treatment of diseases and disorders related to GPR7/8 receptor function or dysfunction.
    Type: Application
    Filed: March 31, 2003
    Publication date: December 18, 2003
    Applicant: Euroscreen, S.A.
    Inventors: Stephane Brezillion, Vincent Lannoy, Vincent Dupriez, Jean-Denis Franssen, Michel Detheux, Marc Parmentier, Emmanuel Le Poul
  • Ligand for G-protein coupled receptor GPR43 and uses thereof
    Publication number: 20030175775
    Abstract: The present invention is related to the G-protein coupled orphan receptor GPR43 and the identification of short chain fatty acids as natural ligands of the receptor. The invention further relates to assays for the identification of agents that modulate GPR43 ligand binding and signalling activity, as well as compositions consisting essentially of an isolated GPR43 polypeptide and an isolated short chain fatty acid. The invention also relates to diagnostic methods and kits that take advantage of the novel interaction of GPR43 with short chain fatty acids.
    Type: Application
    Filed: January 7, 2003
    Publication date: September 18, 2003
    Inventors: Emmanuel LePoul, Michel Detheux, Stephane Brezillon, Vincent Lannoy, Marc Parmentier
  • Compositions and methods comprising G-protein coupled receptors
    Publication number: 20030108986
    Abstract: The present invention relates to G-protein coupled receptors and the nucleic acid molecules encoding them. The invention further relates to methods of screening for compounds which modulate the activity of one or more of the G-protein coupled receptors disclosed herein, and methods for modulating receptor activity. The invention also provides a natural ligand for one or more of the G-protein coupled receptors disclosed herein, and methods for identifying other natural ligands for these receptors.
    Type: Application
    Filed: February 20, 2002
    Publication date: June 12, 2003
    Applicant: Euroscreen, S.A.
    Inventors: Didier Communi, Vincent Lannoy, Stephane Brezillon, Michel Detheux, Marc Parmentier, Cedric Govaerts
  • Receptor GPCRx10
    Publication number: 20030088080
    Abstract: The present invention is related to a novel G-protein coupled receptor having an amino acid sequence which presents more than 75% sequence identity with the sequence SEQ ID NO. 1. The present invention further comprises a method for screening a substance as a potential agonist, reverse agonist, or antagonist to the receptor of the invention. The present invention further comprises a diagnostic method to identify expression of the receptor in target tissues or cells.
    Type: Application
    Filed: June 21, 2001
    Publication date: May 8, 2003
    Inventors: Didier Communi, Vincent Lannoy, Cedric Govaerts, Marc Parmentier, Michel Detheux
  • Natural ligand for orphan G protein coupled receptor GPR86 and methods of use
    Publication number: 20030050235
    Abstract: The present invention is related to a recombinant cell expressing a nucleotide sequence encoding a G protein coupled receptor having an amino acid sequence which presents more than 70% sequence identity with SEQ ID.NO.1 as well as to a drug screening method and kit using the orphan G protein coupled receptor GPR86, identified hereafter as receptor for ADP (P2Y13) and a homologous sequence, the corresponding polynucleotide and said recombinant cell to identify agonist, inverse agonist and antagonist compounds applicable to a diagnostic, prevention and/or treatment of various diseases and disorders.
    Type: Application
    Filed: August 7, 2001
    Publication date: March 13, 2003
    Inventors: Didier Communi, Nathalie Suarez, Michel Detheux, Stephane Brezillion, Vincent Lannoy, Marc Parmentier, Jean-Marie Boeynaems