Patents by Inventor Vincent Laurens Adrianus Kock
Vincent Laurens Adrianus Kock has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240090398Abstract: The invention relates to plants and plant parts, in particular spinach plants (Spinacia oleracea L.), which are resistant to Peronospora farinosa f. sp. spinaciae. The invention also relates to seeds capable of producing Peronospora farinosa f sp. spinaciae resistant plants. The invention further relates to methods for obtaining said plants with altered genotypes and seeds thereof, which are resistant to Peronospora farinosa f sp. spinaciae.Type: ApplicationFiled: July 25, 2023Publication date: March 21, 2024Inventors: Johannes Geert Jan Feitsma, Vincent Laurens Adrianus Kock, Jan Hugo Den Braber
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Patent number: 11751523Abstract: The invention relates to plants and plant parts, in particular spinach plants (Spinacia oleracea L.), which are resistant to Peronospora farinosa f. sp. spinaciae. The invention also relates to seeds capable of producing Peronospora farinosa f. sp. spinaciae resistant plants. The invention further relates to methods for obtaining said plants with altered genotypes and seeds thereof, which are resistant to Peronospora farinosa f sp. spinaciae.Type: GrantFiled: December 18, 2018Date of Patent: September 12, 2023Assignee: RIJK ZWAAN ZAADTEELT EN ZAADHANDEL B.V.Inventors: Johannes Geert Jan Feitsma, Vincent Laurens Adrianus Kock, Jan Hugo Den Braber
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Publication number: 20230257763Abstract: The present invention relates to an allele designated alpha-WOLF 24 which confers resistance to at least one Peronospora farinosa f. sp. spinacea race, wherein the protein encoded by said allele is a CC-NBS-LRR protein that comprises in its amino acid sequence: a) the motif “MAEIGYSVC” (SEQ ID NO: 1) at its N-terminus; and b) the motif “KWMCLR” (SEQ ID NO: 2); and wherein the LRR domain of the protein has in order of increased preference at least 95%, 96%, 97%, 98%, 98.2%, 98.5%, 98.8%, 99%, 100% sequence similarity to SEQ ID NO: 10. The allele when present in a spinach plant confers complete resistance to at least Peronospora farinosa f. sp. spinacea race Pfs:1, Pfs:2, Pfs:5, Pfs:6, Pfs:7, Pfs:9, Pfs:11, Pfs:13, Pfs:15 and Pfs:17, and does not confer resistance to downy mildew race Pfs: 16.Type: ApplicationFiled: August 1, 2022Publication date: August 17, 2023Inventors: Vincent Laurens Adrianus KOCK, Raoul Jacobus Johannes Maria FRIJTERS
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Patent number: 11603538Abstract: The present invention relates to an allele designated alpha-WOLF 25 which confers resistance to at least one Peronospora farinosa f. sp. spinacea race, wherein the protein encoded by said allele is a CC-NB S-LRR protein that comprises in its amino acid sequence: a) the motif “MAEIGYSVC” at its N-terminus; and b) the motif “KWMCLR”; and wherein the LRR domain of the protein has in order of increased preference at least 95%, 96%, 97%, 98%, 99%, 100% sequence similarity to SEQ ID NO: 5. The allele when present in a spinach plant confers complete resistance to at least Peronospora farinosa f sp. spinacea race Pfs:8, Pfs15 and Pfs:16, and does not confer resistance to Pfs:3.Type: GrantFiled: December 20, 2019Date of Patent: March 14, 2023Assignee: RIJK ZWAAN ZAADTEELT EN ZAADHANDEL B.V.Inventors: Raoul Jacobus Johannes Maria Frijters, Vincent Laurens Adrianus Kock
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Publication number: 20220195453Abstract: The present invention relates to a method for modifying the resistance profile of a spinach plant to Peronospora farinosa f. sp. spinaciae, comprising introducing a WOLF allele or a resistance-conferring part thereof into the genome of said spinach plant, or modifying an endogenous WOLF allele in the genome of said spinach plant. The invention further provides a method for selecting a spinach plant comprising a novel WOLF gene that confers resistance to Peronospora farinosa f. sp. spinaciae in a spinach plant and a method for identifying a WOLF allele that confers resistance to one or more pathogenic races of Peronospora farinosa f. sp. spinaciae in a spinach plant and to primers for use in these methods.Type: ApplicationFiled: November 15, 2021Publication date: June 23, 2022Inventors: Vincent Laurens Adrianus Kock, Johannes Geert Jan Feitsma, Raoul Jacobus Johannes Maria Frijters
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Patent number: 11332755Abstract: The present invention relates to a method for modifying the resistance profile of a spinach plant to Peronospora farinosa f sp. spinaciae, comprising introducing a WOLF allele or a resistance-conferring part thereof into the genome of said spinach plant, or modifying an endogenous WOLF allele in the genome of said spinach plant. A WOLF allele encodes a CC-NBS-LRR protein that comprises in its amino acid sequence: the motif “MAEIGYSVC” at its N-terminus, and the motif “KWMCLR” for alpha-type WOLF proteins or “HVGCVVDR” for beta-type WOLF proteins. The invention relates to the WOLF alleles referred to in Table 3. The invention further provides a method for selecting a spinach plant comprising a novel WOLF gene that confers resistance to Peronospora farinosa f sp. spinaciae in a spinach plant and a method for identifying a WOLF allele that confers resistance to one or more pathogenic races of Peronospora farinosa f. sp. spinaciae in a spinach plant and to primers for use in these methods.Type: GrantFiled: January 9, 2020Date of Patent: May 17, 2022Assignee: RIJK ZWAAN ZAADTEELT EN ZAADHANDEL B.V.Inventors: Vincent Laurens Adrianus Kock, Johannes Geert Jan Feitsma, Raoul Jacobus Johannes Maria Frijters
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Patent number: 11254949Abstract: The present invention relates to a method for modifying the resistance profile of a spinach plant to Peronospora farinosa f. sp. spinaciae, comprising introducing a WOLF allele or a resistance-conferring part thereof into the genome of said spinach plant, or modifying an endogenous WOLF allele in the genome of said spinach plant. The invention further provides a method for selecting a spinach plant comprising a novel WOLF gene that confers resistance to Peronospora farinosa f. sp. spinaciae in a spinach plant and a method for identifying a WOLF allele that confers resistance to one or more pathogenic races of Peronospora farinosa f. sp. spinaciae in a spinach plant and to primers for use in these methods.Type: GrantFiled: March 22, 2019Date of Patent: February 22, 2022Assignee: RIJK ZWAAN ZAADTEELT EN ZAADHANDEL B.V.Inventors: Vincent Laurens Adrianus Kock, Johannes Geert Jan Feitsma, Raoul Jacobus Johannes Maria Frijters
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Publication number: 20210403937Abstract: The present invention relates to an allele designated alpha-CMV which confers resistance to CMV when present in a spinach plant, wherein the protein encoded by said allele is a CC-NBS-LRR protein that comprises in its amino acid sequence: a) the motif “MAEIGYSVC” (SEQ ID NO: 22) at its N-terminus; and b) the motif “KWMCLR” (SEQ ID NO: 23); and c) an LRR domain that has in order of increased preference at least 95%, 96%, 97%, 98%, 99%, 100% sequence similarity to SEQ ID NO: 10. The allele has a genomic nucleotide sequence which in order of increased preference has at least 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, 100% sequence similarity to SEQ ID NO: 1. The invention further relates to plants comprising the allele and to various methods involving the allele.Type: ApplicationFiled: September 14, 2021Publication date: December 30, 2021Inventors: Vincent Laurens Adrianus Kock, Johannes Geert Jan Feitsma, Raoul Jacobus Johannes Maria FRIJTERS
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Patent number: 11203766Abstract: The present invention relates to an allele designated alpha-WOLF 15 which confers resistance to at least one Peronospora farinosa f. Sp. spinacea race, wherein the protein encoded by said allele is a CC-NBS-LRR protein that comprises in its amino acid sequence: a) the motif “MAEIGYSVC” (SEQ ID NO: 13) at its N-terminus; and b) the motif “KWMCLR” (SEQ ID NO: 14); and wherein the LRR domain of the protein has in order of increased preference at least 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, 100% sequence similarity to SEQ ID NO: 10. The allele when homozygously present in a spinach plant confers complete resistance to Peronospora farinosa f. Sp. spinacea races pfs:1, pfs:2, pfs:3, pfs:4 and pfs:5, pfs:6, pfs:8, pfs:9, pfs:11, pfs:12, pfs:13, pfs:14, pfs:15, pfs:16 and isolates UA1014 and US1508, and confers intermediate resistance to pfs:10, and does not confer resistance to pfs:7.Type: GrantFiled: March 22, 2019Date of Patent: December 21, 2021Assignee: RIJK ZWAAN ZAADTEELT EN ZAADHANDEL B.V.Inventors: Vincent Laurens Adrianus Kock, Raoul Jacobus Johannes Maria Frijters, Johannes Geert Jan Feitsma
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Patent number: 11202421Abstract: The present invention relates to an allele designated alpha-WOLF 8 which confers resistance to at least one Peronospora farinosa f. Sp. spinacea race, wherein the protein encoded by said allele is a CC-NB S-LRR protein that comprises in its amino acid sequence: a) the motif “MAEIGYSVC” (SEQ ID NO: 15) at its N-terminus; and b) the motif “KWMCLR” (SEQ ID NO: 16); and wherein the LRR domain of the protein has in order of increased preference at least 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, 100% sequence similarity to SEQ ID NO: 12. When the allele is homozygously present in a spinach plant confers complete resistance to Peronospora farinosa f. Sp. spinacea races pfs:1, pfs:2, pfs:6, pfs:8 and pfs:15, and isolate US1508, and confers intermediate resistance to pfs:5, pfs:10 and pfs:16, and does not confer resistance to pfs:3, pfs:4, pfs:7, pfs:9, pfs:11, pfs:12, pfs:13 and pfs:14.Type: GrantFiled: March 22, 2019Date of Patent: December 21, 2021Assignee: RIJK ZWAAN ZAADTEELT EN ZAADHANDEK B.V.Inventors: Vincent Laurens Adrianus Kock, Johannes Geert Jan Feitsma, Raoul Jacobus Johannes Maria Frijters
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Patent number: 11136592Abstract: The present invention relates to an allele designated alpha-CMV which confers resistance to CMV when present in a spinach plant, wherein the protein encoded by said allele is a CC-NBS-LRR protein that comprises in its amino acid sequence: a) the motif “MAEIGYSVC” (SEQ ID NO: 22) at its N-terminus; and b) the motif “KWMCLR” (SEQ ID NO: 23); and c) an LRR domain that has in order of increased preference at least 95%, 96%, 97%, 98%, 99%, 100% sequence similarity to SEQ ID NO: 10. The allele has a genomic nucleotide sequence which in order of increased preference has at least 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, 100% sequence similarity to SEQ ID NO: 1. The invention further relates to plants comprising the allele and to various methods involving the allele.Type: GrantFiled: February 19, 2019Date of Patent: October 5, 2021Assignee: RIJK ZWAAN ZAADTEELT EN ZAADHANDEL B.V.Inventors: Vincent Laurens Adrianus Kock, Johannes Geert Jan Feitsma, Raoul Jacobus Johannes Maria Frijters
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Publication number: 20210282345Abstract: The present invention relates to an allele designated alpha-WOLF 24 which confers resistance to at least one Peronospora farinosa f. sp. spinacea race, wherein the protein encoded by said allele is a CC-NBS-LRR protein that comprises in its amino acid sequence: a) the motif “MAEIGYSVC” SEQ ID NO: 1 at its N-terminus; and b) the motif “KWMCLR” SEQ ID NO: 2; and wherein the LRR domain of the protein has in order of increased preference at least 95%, 96%, 97%, 98%, 98.2%, 98.5%, 98.8%, 99%, 100% sequence similarity to SEQ ID NO: 10. The allele when present in a spinach plant confers complete resistance to at least Peronospora farinosa f. sp. spinacea race Pfs:1, Pfs:2, Pfs:5, Pfs:6, Pfs:7, Pfs:9, Pfs:11, Pfs:13, Pfs:15 and Pfs:17, and does not confer resistance to downy mildew race Pfs:16.Type: ApplicationFiled: March 12, 2021Publication date: September 16, 2021Inventors: Vincent Laurens Adrianus Kock, Raoul Jacobus Johannes Maria Frijters
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Publication number: 20200318131Abstract: The present invention relates to a method for modifying the resistance profile of a spinach plant to Peronospora farinosa f sp. spinaciae, comprising introducing a WOLF allele or a resistance-conferring part thereof into the genome of said spinach plant, or modifying an endogenous WOLF allele in the genome of said spinach plant. A WOLF allele encodes a CC-NBS-LRR protein that comprises in its amino acid sequence: the motif “MAEIGYSVC” at its N-terminus, and the motif “KWMCLR” for alpha-type WOLF proteins or “HVGCVVDR” for beta-type WOLF proteins. The invention relates to the WOLF alleles referred to in Table 3. The invention further provides a method for selecting a spinach plant comprising a novel WOLF gene that confers resistance to Peronospora farinosa f sp. spinaciae in a spinach plant and a method for identifying a WOLF allele that confers resistance to one or more pathogenic races of Peronospora farinosa f. sp. spinaciae in a spinach plant and to primers for use in these methods.Type: ApplicationFiled: January 9, 2020Publication date: October 8, 2020Inventors: Vincent Laurens Adrianus Kock, Johannes Geert Jan Feitsma, Raoul Jacobus Johannes Maria Frijters
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Publication number: 20200236887Abstract: The present invention relates to an allele designated alpha-WOLF 15 which confers resistance to at least one Peronospora farinosa f. sp. spinaciae race, wherein the protein encoded by said allele is a CC-NBS-LRR protein that comprises in its amino acid sequence: a) the motif “MAEIGYSVC” (SEQ ID NO:13) at its N-terminus; and b) the motif “KWMCLR” (SEQ ID NO:14; and wherein the LRR domain of the protein has in order of increased preference at least 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, 100% sequence similarity to SEQ ID NO:10. The allele when homozygously present in a spinach plant confers complete resistance to Peronospora farinosa f. sp. spinaciae races Pfs:1, Pfs:2, Pfs:3, Pfs:4 and Pfs:5, Pfs:6, Pfs:8, Pfs:9, Pfs:11, Pfs:12, Pfs:13, Pfs:14, Pfs:15 and isolates UA1014, and confers intermediate resistance to pfs:10, and does not confer resistance to Pfs:7 and Pfs:16.Type: ApplicationFiled: March 25, 2020Publication date: July 30, 2020Inventors: Johannes Geert Jan Feitsma, Vincent Laurens Adrianus Kock
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Publication number: 20200199615Abstract: The present invention relates to an allele designated alpha-WOLF 25 which confers resistance to at least one Peronospora farinosa f. sp. spinacea race, wherein the protein encoded by said allele is a CC-NBS-LRR protein that comprises in its amino acid sequence: a) the motif “MAEIGYSVC” at its N-terminus; and b) the motif “KWMCLR”; and wherein the LRR domain of the protein has in order of increased preference at least 95%, 96%, 97%, 98%, 99%, 100% sequence similarity to SEQ ID NO: 5. The allele when present in a spinach plant confers complete resistance to at least Peronospora farinosa f. sp. spinacea race Pfs:8, Pfs15 and Pfs:16, and does not confer resistance to Pfs:3.Type: ApplicationFiled: December 20, 2019Publication date: June 25, 2020Inventors: Raoul Jacobus Johannes Maria FRIJTERS, Vincent Laurens Adrianus KOCK
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Patent number: 10674688Abstract: The present invention relates to an allele designated alpha-WOLF 8 which confers resistance to at least one Peronospora farinosa f. sp. spinaciae race, wherein the protein encoded by said allele is a CC-NB S-LRR protein that comprises in its amino acid sequence: a) the motif “MAEIGYSVC” (SEQ ID NO: 15) at its N-terminus; and b) the motif “KWMCLR” (SEQ ID NO: 16); and wherein the LRR domain of the protein has in order of increased preference at least 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, 100% sequence similarity to SEQ ID NO: 12. When the allele is homozygously present in a spinach plant confers complete resistance to Peronospora farinosa f. sp. spinaciae races Pfs:1, Pfs:2, Pfs:6, Pfs:8 and Pfs:15, and confers intermediate resistance to Pfs:5, Pfs:10 and Pfs:16, and does not confer resistance to Pfs:3, Pfs:4, Pfs:7, Pfs:9, Pfs:11, Pfs:12, Pfs:13 and Pfs:14.Type: GrantFiled: September 29, 2017Date of Patent: June 9, 2020Assignee: RIJK ZWAAN ZAADTEELT EN ZAADHANDEL B.V.Inventors: Vincent Laurens Adrianus Kock, Johannes Geert Jan Feitsma, Raoul Jacobus Johannes Maria Frijters
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Patent number: 10638688Abstract: The present invention relates to an allele designated alpha-WOLF 15 which confers resistance to at least one Peronospora farinosa f sp. spinaciae race, wherein the protein encoded by said allele is a CC-NB S-LRR protein that comprises in its amino acid sequence: a) the motif “MAEIGYSVC” (SEQ ID NO: 13) at its N-terminus; and b) the motif “KWMCLR” (SEQ ID NO: 14); and wherein the LRR domain of the protein has in order of increased preference at least 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, 100% sequence similarity to SEQ ID No:10. The allele when homozygously present in a spinach plant confers complete resistance to Peronospora farinosa f sp. spinaciae races Pfs:1, Pfs:2, Pfs:3, Pfs:4 and Pfs: 5, Pfs:6, Pfs:8, Pfs:9, Pfs:11, Pfs:12, Pfs:13, Pfs:14, Pfs:15, and isolates UA1014, and confers intermediate resistance to Pfs:10, and does not confer resistance to Pfs:7 and Pfs: 16.Type: GrantFiled: September 29, 2017Date of Patent: May 5, 2020Assignee: RIJK ZWAAN ZAADTEELT EN ZAADHANDEL B.V.Inventors: Johannes Geert Jan Feitsma, Vincent Laurens Adrianus Kock
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Patent number: 10633670Abstract: The present invention relates to a method for modifying the resistance profile of a spinach plant to Peronospora farinosa f. sp. spinaciae, comprising introducing a WOLF allele or a resistance-conferring part thereof into the genome of said spinach plant, or modifying an endogenous WOLF allele in the genome of said spinach plant. A WOLF allele encodes a CC-NBS-LRR protein that comprises in its amino acid sequence: the motif “MAEIGYSVC” at its N-terminus, and the motif “KWMCLR” for alpha-type WOLF proteins or “HVGCVVDR” for beta-type WOLF proteins. The invention relates to the WOLF alleles referred to in Table 3. The invention further provides a method for selecting a spinach plant comprising a novel WOLF gene that confers resistance to Peronospora farinosa f. sp. spinaciae in a spinach plant and a method for identifying a WOLF allele that confers resistance to one or more pathogenic races of Peronospora farinosa f. sp. spinaciae in a spinach plant and to primers for use in these methods.Type: GrantFiled: September 29, 2017Date of Patent: April 28, 2020Assignee: RIJK ZWAAN ZAADTEELT EN ZAADHANDEL B.V.Inventors: Vincent Laurens Adrianus Kock, Johannes Geert Jan Feitsma, Raoul Jacobus Johannes Maria Frijters
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Publication number: 20200017875Abstract: The present invention relates to an allele designated alpha-WOLF 8 which confers resistance to at least one Peronospora farinosa f. Sp. spinacea race, wherein the protein encoded by said allele is a CC-NBS-LRR protein that may comprise in its amino acid sequence: a) the motif “MAEIGYSVC” at its N-terminus; and b) the motif “KWMCLR”; and wherein the LRR domain of the protein has in order of increased preference at least 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, 100% sequence similarity to SEQ ID No:12. When the allele is homozygously present in a spinach plant confers complete resistance to Peronospora farinosa f. Sp. spinacea races pfs:1, pfs:2, pfs:6, pfs:8 and pfs:15, and confers intermediate resistance to pfs:5, pfs:10 and pfs:16, and does not confer resistance to pfs:3, pfs:4, pfs:7, pfs:9, pfs:11, pfs:12, pfs:13 and pfs:14.Type: ApplicationFiled: March 22, 2019Publication date: January 16, 2020Inventors: Vincent Laurens Adrianus Kock, Johannes Geert Jan Feitsma, Raoul Jacobus Johannes Maria Frijters
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Publication number: 20190241905Abstract: The present invention relates to a method for modifying the resistance profile of a spinach plant to Peronospora farinosa f sp. spinaciae, comprising introducing a WOLF allele or a resistance-conferring part thereof into the genome of said spinach plant, or modifying an endogenous WOLF allele in the genome of said spinach plant. A WOLF allele encodes a CC-NBS-LRR protein that comprises in its amino acid sequence: the motif “MAEIGYSVC” at its N-terminus, and the motif “KWMCLR” for alpha-type WOLF proteins or “HVGCVVDR” for beta-type WOLF proteins. The invention relates to the WOLF alleles referred to in Table 3. The invention further provides a method for selecting a spinach plant comprising a novel WOLF gene that confers resistance to Peronospora farinosa f. sp. spinaciae in a spinach plant and a method for identifying a WOLF allele that confers resistance to one or more pathogenic races of Peronospora farinosa f sp. spinaciae in a spinach plant and to primers for use in these methods.Type: ApplicationFiled: March 22, 2019Publication date: August 8, 2019Inventors: Vincent Laurens Adrianus Kock, Johannes Geert Jan Feitsma, Raoul Jacobus Johannes Maria Frijters