Abstract: A document review system that displays a workflow builder interface comprising a block library and a workflow canvas. The system receives user selection of workflow blocks including rule execution blocks, conditional logic blocks, and output blocks, enables positioning of the blocks on the canvas, and receives user-defined connections between blocks. The system receives natural language rule definitions through prompt fields and document selections through context selectors, processes the rule definitions using an artificial intelligence engine to generate executable operations, receives conditional expressions for workflow branching logic, configures output parameters, and executes workflows defined by the positioned blocks and connections.

Abstract: A method of operating a surround view camera system for a vehicle includes generating first image data at a first time using an imaging device, the first image data corresponding to a first image of a surroundings of the vehicle, and receiving first vehicle data generated by at least one sensor of the vehicle with a processor, the first vehicle data generated at the first time. The method further includes generating second image data at a second time after the first time using the imaging device, the second image data corresponding to a second image of the surroundings of the vehicle, and receiving second vehicle data generated by the at least one sensor with the processor, the second vehicle data generated from the first time to the second time. The method also includes processing the first vehicle data and the second vehicle data using the processor to determine change data.

Abstract: The present disclosure provides a document review and approval system comprising a user interface with a source selector, an objective definer, and a corpus selector for receiving source documents, user-defined objectives, and policy documents, respectively. An artificial intelligence engine processes the received inputs. Output interfaces include a syntax auditor for identifying and facilitating correction of syntax errors, a policy auditor for identifying non-compliance issues with policies, and a reporter for generating reports based on findings. The system enables efficient review and approval of documents for both syntax and policy compliance, utilizing artificial intelligence to process natural language inputs and generate outputs, including explanations for identified issues and natural language summaries in generated reports.

Abstract: A method of operating a surround view camera system for a vehicle includes generating first image data at a first time using an imaging device, the first image data corresponding to a first image of a surroundings of the vehicle, and receiving first vehicle data generated by at least one sensor of the vehicle with a processor, the first vehicle data generated at the first time. The method further includes generating second image data at a second time after the first time using the imaging device, the second image data corresponding to a second image of the surroundings of the vehicle, and receiving second vehicle data generated by the at least one sensor with the processor, the second vehicle data generated from the first time to the second time. The method also includes processing the first vehicle data and the second vehicle data using the processor to determine change data.

Abstract: The invention provides the three-dimensional structure of a construct of glycogen synthase kinase 3 (GSK3); crystals of a construct of glycogen synthase kinase 3-? (GSK3-?) containing the protein's catalytic kinase domain; a method for crystallizing the protein construct to provide a GSK3 crystal sufficient for structure determination; and a method for using the GSK3 construct's three-dimensional structure for the identification of possible therapeutic compounds in the treatment of various disease conditions mediated by GSK3 activity.

Abstract: The invention provides the three-dimensional structure of a construct of human glycogen synthase kinase 3 (GSK3); crystals of a construct of human glycogen synthase kinase 3-? (GSK3-?) containing the protein's catalytic kinase domain; a method for crystallizing the protein construct to provide a GSK3 crystal sufficient for structure determination; and a method for using the GSK3 construct's three-dimensional structure for the identification of possible therapeutic compounds in the treatment of various disease conditions mediated by GSK3 activity.

Abstract: The invention provides the three-dimensional structure of a construct of human glycogen synthase kinase 3 (GSK3); crystals of a construct of human glycogen synthase kinase 3-? (GSK3-?) containing the protein's catalytic kinase domain; a method for crystallizing the protein construct to provide a GSK3 crystal sufficient for structure determination; and a method for using the GSK3 construct's three-dimensional structure for the identification of possible therapeutic compounds in the treatment of various disease conditions mediated by GSK3 activity.

Abstract: The present invention relates to new substituted imidazole compounds and pharmaceutically acceptable salts, esters or prodrugs thereof, compositions of the new compounds together with pharmaceutically acceptable carriers, and uses of the new compounds.

Abstract: Compounds of Structure I, and salts, tautomers, stereoisomers, and mixtures thereof may be used in methods of inhibiting checkpoint kinase 1 in subjects, in methods for inducing cell cycle progression, and in methods for increasing apoptosis in cells. Such compounds may be used to prepare pharmaceutical compositions and may be used in conjunction with DNA damaging agents.